2R9U | pdb_00002r9u

Crystal Structure of Lamprey Variable Lymphocyte Receptor 2913 Ectodomain

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
D	d2r9ud1	Alpha and beta proteins (a/b)	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	L domain-like	automated matches	automated matches	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)
D	d2r9ud2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)
C	d2r9uc1	Alpha and beta proteins (a/b)	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	L domain-like	automated matches	automated matches	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)
C	d2r9uc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)
B	d2r9ub1	Alpha and beta proteins (a/b)	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	L domain-like	automated matches	automated matches	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)
B	d2r9ub2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)
A	d2r9ua1	Alpha and beta proteins (a/b)	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	L domain-like	automated matches	automated matches	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)
A	d2r9ua2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Sea lamprey (Petromyzon marinus ) [TaxId: 7757 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
D	SCOP2B Superfamily	L domain-like	8095997	3001010	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	L domain-like	8095997	3001010	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	L domain-like	8095997	3001010	SCOP2B (2022-06-29)
A	SCOP2 Family	Ngr ectodomain-like	8047120	4002278	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	L domain-like	8095997	3001010	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	LRR_8_1	e2r9uD1	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Leucine-rich repeats (From Topology)	T: Leucine-rich repeats	F: LRR_8_1	ECOD (1.6)
C	LRR_8_1	e2r9uC1	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Leucine-rich repeats (From Topology)	T: Leucine-rich repeats	F: LRR_8_1	ECOD (1.6)
B	LRR_8_1	e2r9uB1	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Leucine-rich repeats (From Topology)	T: Leucine-rich repeats	F: LRR_8_1	ECOD (1.6)
A	LRR_8_1	e2r9uA1	A: beta duplicates or obligate multimers	X: Single-stranded right-handed beta-helix	H: Leucine-rich repeats (From Topology)	T: Leucine-rich repeats	F: LRR_8_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
D	3.80.10.10	Alpha Beta	Alpha-Beta Horseshoe	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	Ribonuclease Inhibitor	CATH (4.3.0)
C	3.80.10.10	Alpha Beta	Alpha-Beta Horseshoe	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	Ribonuclease Inhibitor	CATH (4.3.0)
B	3.80.10.10	Alpha Beta	Alpha-Beta Horseshoe	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	Ribonuclease Inhibitor	CATH (4.3.0)
A	3.80.10.10	Alpha Beta	Alpha-Beta Horseshoe	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	Ribonuclease Inhibitor	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF13855	Leucine rich repeat (LRR_8)	Leucine rich repeat	-	Repeat
A, B, C, D	PF11921	Domain of unknown function (DUF3439) (DUF3439)	Domain of unknown function (DUF3439)	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Variable lymphocyte receptor	-	-	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR032675	Leucine-rich repeat domain superfamily	Homologous Superfamily
A, B, C, D	IPR000372	Leucine-rich repeat N-terminal domain	Domain
A, B, C, D	IPR024592	Variable lymphocyte receptor, C-terminal	Domain
A, B, C, D	IPR001611	Leucine-rich repeat	Repeat
A, B, C, D	IPR050541	Leucine-rich repeat and transmembrane domain-containing protein	Family
A, B, C, D	IPR003591	Leucine-rich repeat, typical subtype	Repeat

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.