Annotations: 5ZM5

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Oxysterol_BP	e5zm5A1	A: beta barrels	X: Oxysterol-binding protein (From Topology)	H: Oxysterol-binding protein (From Topology)	T: Oxysterol-binding protein	F: Oxysterol_BP	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01237	Oxysterol-binding protein (Oxysterol_BP)	Oxysterol-binding protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Oxysterol-binding protein-related protein 1	sterol binding binding alcohol binding steroid binding lipid binding cholesterol binding small molecule binding sterol transfer activity lipid transporter activity lipid transfer activity transporter activity phospholipid binding	bile acid biosynthetic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process steroid metabolic process carboxylic acid metabolic process primary metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process bile acid metabolic process biosynthetic process small molecule metabolic process metabolic process bile acid biosynthetic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process steroid metabolic process carboxylic acid metabolic process primary metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process bile acid metabolic process biosynthetic process small molecule metabolic process metabolic process cellular process monocarboxylic acid metabolic process lipid metabolic process localization transport establishment of localization vesicle-mediated transport secondary alcohol metabolic process sterol metabolic process cholesterol metabolic process alcohol metabolic process	membrane-bounded organelle intracellular anatomical structure endosome intracellular vesicle intracellular membrane-bounded organelle endomembrane system intracellular organelle cellular anatomical structure cytoplasmic vesicle organelle cytoplasm vesicle extracellular exosome extracellular vesicle membrane-bounded organelle intracellular anatomical structure endosome intracellular vesicle intracellular membrane-bounded organelle endomembrane system intracellular organelle cellular anatomical structure cytoplasmic vesicle organelle cytoplasm vesicle extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space extracellular membrane-bounded organelle cytosol cell periphery plasma membrane membrane late endosome organelle membrane contact site perinuclear endoplasmic reticulum perinuclear region of cytoplasm endoplasmic reticulum

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002110	Ankyrin repeat	Repeat
A	IPR001849	Pleckstrin homology domain	Domain
A	IPR018494	Oxysterol-binding protein, conserved site	Conserved Site
A	IPR036770	Ankyrin repeat-containing domain superfamily	Homologous Superfamily
A	IPR037239	Oxysterol-binding protein superfamily	Homologous Superfamily
A	IPR000648	Oxysterol-binding protein	Family
A	IPR011993	PH-like domain superfamily	Homologous Superfamily

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: Q9BXW6	pituitary cancer spina bifida ulcerative colitis Alzheimer disease atypical teratoid rhabdoid tumor glioblastoma lung cancer malignant glioma medulloblastoma pancreatic intraductal papillary-mucinous neoplasm primitive neuroectodermal tumor tuberculosis astrocytic tumor cystic fibrosis invasive ductal breast carcinoma pituitary cancer spina bifida ulcerative colitis Alzheimer disease atypical teratoid rhabdoid tumor glioblastoma lung cancer malignant glioma medulloblastoma pancreatic intraductal papillary-mucinous neoplasm primitive neuroectodermal tumor tuberculosis astrocytic tumor cystic fibrosis invasive ductal breast carcinoma malignant colon neoplasm malignant mesothelioma oligodendroglioma pilocytic astrocytoma psoriasis type 2 diabetes mellitus atopic eczema ductal breast carcinoma in situ large cell medulloblastoma malignant ependymoma maturity-onset diabetes of the young ovarian cancer

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.