7BSC | pdb_00007bsc

Complex structure of 1G5.3 Fab bound to DENV2 NS1c

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
B [auth H]d7bsch_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
C [auth L]d7bscl2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
C [auth L]d7bscl1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyZIKV NS1 beta-ladder domain-like 8102191 4006115 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyZIKV NS1 beta-ladder domain-like 8102192 3002411 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AFlavi_NS1_Ce7bscA1 A: beta meandersX: Flavivirus non-structural protein 1 (NS1) beta-meander domain (From Topology)H: Flavivirus non-structural protein 1 (NS1) beta-meander domain (From Topology)T: Flavivirus non-structural protein 1 (NS1) beta-meander domainF: Flavi_NS1_CECOD (1.6)
B [auth H]V-set_8e7bscH2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
B [auth H]C1-set_1e7bscH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
C [auth L]C1-set_4e7bscL1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
C [auth L]V-sete7bscL2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B [auth H]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (utative)
C [auth L]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (utative)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
B [auth H]Heavy ChainIGHV3 -non-structural protein 1SAbDab (2025-08-22)
C [auth L]Light ChainIGKV3 Kappanon-structural protein 1SAbDab (2025-08-22)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Non-structural protein 1- -
B [auth H]1G5.3 Fab Heavy Chain---
C [auth L]1G5.3 Fab Light Chain---

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR001157Non-structural protein NS1, flavivirusDomain