9CA3 | pdb_00009ca3

Crystal structure of MarE C280S in complex with cyanide bound heme and its native substrate, beta-methyl-L-tryptophan

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Tryptophan 2,3-dioxygenase	oxidoreductase activity catalytic activity dioxygenase activity binding tetrapyrrole binding heme binding cation binding ion binding metal ion binding small molecule binding	catabolic process oxoacid metabolic process ketone metabolic process aromatic amino acid family catabolic process indole-containing compound metabolic process amino acid metabolic process organic acid catabolic process organic acid metabolic process alpha-amino acid metabolic process non-proteinogenic amino acid metabolic process L-tryptophan metabolic process carboxylic acid catabolic process indolalkylamine metabolic process small molecule metabolic process catabolic process oxoacid metabolic process ketone metabolic process aromatic amino acid family catabolic process indole-containing compound metabolic process amino acid metabolic process organic acid catabolic process organic acid metabolic process alpha-amino acid metabolic process non-proteinogenic amino acid metabolic process L-tryptophan metabolic process carboxylic acid catabolic process indolalkylamine metabolic process small molecule metabolic process amino acid catabolic process L-tryptophan catabolic process to kynurenine erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process aromatic amino acid metabolic process benzene-containing compound metabolic process carboxylic acid metabolic process L-amino acid catabolic process primary metabolic process L-tryptophan catabolic process L-amino acid metabolic process proteinogenic amino acid metabolic process amine metabolic process kynurenine metabolic process erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process alpha-amino acid catabolic process proteinogenic amino acid catabolic process indole-containing compound catabolic process metabolic process cellular process small molecule catabolic process biogenic amine metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR037217	Tryptophan/Indoleamine 2,3-dioxygenase-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.