Annotations: 9JAF

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Guanylate kinase	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding nucleobase-containing compound kinase activity nucleoside monophosphate kinase activity kinase activity transferase activity catalytic activity phosphotransferase activity, phosphate group as acceptor GMP kinase activity transferase activity, transferring phosphorus-containing groups	nucleoside phosphate metabolic process primary metabolic process nucleotide metabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process purine nucleotide metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process cellular process small molecule metabolic process phosphorus metabolic process cellular response to stimulus nucleoside phosphate metabolic process primary metabolic process nucleotide metabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process purine nucleotide metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process cellular process small molecule metabolic process phosphorus metabolic process cellular response to stimulus cellular response to chemical stimulus response to stimulus response to chemical cellular response to xenobiotic stimulus xenobiotic metabolic process response to xenobiotic stimulus nucleotide-sugar metabolic process carbohydrate derivative metabolic process GDP-mannose metabolic process 2'-deoxyribonucleotide metabolic process purine deoxyribonucleoside monophosphate metabolic process deoxyribonucleotide metabolic process dGMP metabolic process purine deoxyribonucleotide metabolic process purine nucleoside monophosphate metabolic process nucleoside monophosphate metabolic process nucleobase-containing small molecule interconversion localization establishment of protein localization nitrogen compound transport transport protein transport glycoprotein transport macromolecule localization intracellular protein localization carbohydrate derivative transport establishment of localization purine nucleoside triphosphate metabolic process purine deoxyribonucleoside triphosphate metabolic process dATP metabolic process nucleoside triphosphate metabolic process deoxyribonucleoside triphosphate metabolic process dGDP biosynthetic process dGDP metabolic process deoxyribose phosphate biosynthetic process nucleotide biosynthetic process nucleoside diphosphate biosynthetic process purine deoxyribonucleoside diphosphate metabolic process deoxyribonucleotide biosynthetic process purine-containing compound biosynthetic process deoxyribonucleoside diphosphate biosynthetic process carbohydrate derivative biosynthetic process purine nucleoside diphosphate metabolic process 2'-deoxyribonucleotide biosynthetic process purine nucleoside diphosphate biosynthetic process nucleobase-containing compound biosynthetic process nucleoside diphosphate metabolic process biosynthetic process organophosphate biosynthetic process nucleoside phosphate biosynthetic process purine deoxyribonucleotide biosynthetic process purine deoxyribonucleoside diphosphate biosynthetic process purine nucleotide biosynthetic process ribose phosphate metabolic process purine ribonucleotide biosynthetic process purine ribonucleoside diphosphate biosynthetic process ribonucleotide biosynthetic process ribonucleotide metabolic process ribonucleoside diphosphate metabolic process ribose phosphate biosynthetic process GDP biosynthetic process purine ribonucleoside diphosphate metabolic process purine ribonucleotide metabolic process GDP metabolic process ribonucleoside diphosphate biosynthetic process	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle photoreceptor inner segment cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR008145	Guanylate kinase/L-type calcium channel beta subunit	Domain
A, B	IPR017665	Guanylate kinase	Family
A, B	IPR020590	Guanylate kinase, conserved site	Conserved Site
A, B	IPR008144	Guanylate kinase-like domain	Domain
A, B	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B	Pharos: Q16774	astrocytic tumor idiopathic scoliosis ovarian cancer plasma cell myeloma breast cancer malignant pancreatic neoplasm pancreatic ductal adenocarcinoma primary cutaneous T-cell non-Hodgkin lymphoma diabetes mellitus MALT lymphoma Pick disease

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.