9NTJ | pdb_00009ntj

Chimeric Adenosine deaminase growth factor (ADGF) in complex with pentostatin

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00962	Adenosine deaminase (A_deaminase)	Adenosine deaminase		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Adenosine deaminase AGSA,Adenosine deaminase AGSA,AMP deaminase	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines adenosine deaminase activity hydrolase activity catalytic activity deaminase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cation binding ion binding binding metal ion binding small molecule binding	glycosyl compound metabolic process catabolic process purine nucleoside catabolic process carbohydrate derivative metabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process small molecule metabolic process purine ribonucleoside metabolic process carbohydrate derivative catabolic process adenosine catabolic process primary metabolic process glycosyl compound catabolic process purine-containing compound catabolic process nucleoside metabolic process glycosyl compound metabolic process catabolic process purine nucleoside catabolic process carbohydrate derivative metabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process small molecule metabolic process purine ribonucleoside metabolic process carbohydrate derivative catabolic process adenosine catabolic process primary metabolic process glycosyl compound catabolic process purine-containing compound catabolic process nucleoside metabolic process nucleobase-containing compound catabolic process purine-containing compound metabolic process adenosine metabolic process nucleobase-containing small molecule catabolic process nucleoside catabolic process metabolic process cellular process small molecule catabolic process ribonucleoside catabolic process purine nucleoside metabolic process purine ribonucleoside catabolic process ribonucleoside metabolic process nucleoside biosynthetic process purine-containing compound biosynthetic process carbohydrate derivative biosynthetic process glycosyl compound biosynthetic process inosine metabolic process small molecule biosynthetic process purine ribonucleoside biosynthetic process ribonucleoside biosynthetic process nucleobase-containing compound biosynthetic process nucleobase-containing small molecule biosynthetic process inosine biosynthetic process biosynthetic process purine nucleoside biosynthetic process	cellular anatomical structure extracellular region extracellular space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR013659	Adenosine/AMP deaminase N-terminal	Domain
A, B	IPR001365	Adenosine deaminase domain	Domain
A, B	IPR006331	Adenosine deaminase-related growth factor	Family
A, B	IPR006330	Adenosine/adenine deaminase	Family
A, B	IPR032466	Metal-dependent hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.