Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia.[L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient.[L42340] Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996.[A249885] Sevoflurane is three times more potent than [desflurane], but has lower potency compared to [halothane] and [isoflurane]. Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients receiving this anesthetic agent present little toxicity.[A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety of anesthetic procedures.[A249885]
Synonyms
Sevofluran
Sevofluranum
Sevoflurane
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
Sevoflurano
Brand Names
Sojourn
Sevorane AF
Sevoflurane
Ultane
Truemed Group LLC
Sevoflurane Bostonbio
Indication
Sevoflurane is used for the induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.[L42340]
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
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