AIN

2-(ACETYLOXY)BENZOIC ACID

Created:	2004-04-08
Last modified:	2020-05-26

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8 entries where AIN is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	21
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	6

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Chemical Component Summary
Name	2-(ACETYLOXY)BENZOIC ACID
Synonyms	ACETYLSALICYLIC ACID; ASPIRIN
Systematic Name (OpenEye OEToolkits)	2-acetyloxybenzoic acid
Formula	C₉ H₈ O₄
Molecular Weight	180.157
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(Oc1ccccc1C(=O)O)C
SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
Canonical SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
InChI	InChI	1.03	InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChIKey	InChI	1.03	BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00945
Name	Acetylsalicylic acid
Groups	approved vet_approved
Description	Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Synonyms	Azetylsalizylsäure Acetylsalicylic acid o-acetoxybenzoic acid Aspirina Polopiryna O-acetylsalicylic acid 2-Acetoxybenzenecarboxylic acid Acide acétylsalicylique Acetylsalicylate Acidum acetylsalicylicum ASA Lysine acetylsalicylate ácido acetilsalicílico acide 2-(acétyloxy)benzoïque Acetylsalicylsäure 2-Acetoxybenzoic acid Salicylic acid acetate Aspirin o-carboxyphenyl acetate
Brand Names	Bayer Rapid Relief 217 Strong Tab Micro-Coated Aspirin Novo Ac and C 8mg Tab Publix Super Markets Inc Cardiospirina 81 mg Tabletas con cubierta enterica Vanquish Digital Headache Asprin and Extended-release Dipyridamole pain relief aspirin Low Dose Leader Effervescent Antacid and Pain Relief Walgreens Antacid Pain Relief Extra Strength Extra Strength Pain Reliever Value PharmaPain Reliever Extra Strength Pro-aas EC Bayer Womens 4246 First Aid Kit Low dose Chewable Aspirin Entrophen Low Dose Aspirin Low Dose Pain Away Plus 4376 First Aid Kit Ready America First Aid Pocket - 33 Pieces Robaxisal Caplets Asaphen EC Aspirin Extra Strength 500mg Tab USP Tri-Buffered Aspirin Coated Daily Low Dose Asa 81 mg GOOD NEIGHBOR PHARMACY FIRST AID Contains 202 PIECES Pain Stoppers Asasantine Cap Muscle Relaxant and Analgesic 282 Mep Tab Apo-asa Ld Seedalmerk Signature Care Effervescent Antacid and Pain Relief Low dose Aspirin Asadol 325mg Aspirin 325 MEDIQUE Aspirin GENUINE FIRST AID Emergency Preparedness Contains 167 PIECES HARDCASE DG Health migraine relief London Drugs Coated Daily Low-dose Asa ConRx pain Reliever Aspirin Adult Low Strength Aspirin Aspirin Enteric Safety-Coated Healthy Accents migraine formula Critical Care Aspirin to Go Halfprin Low Dose Aspirin Natural Aspirin plus Lemon and Honey Dietary Supplement Extra Pain Reliever Aspirin Enteric Enteric Coated Aspirin Coated Aspirin Low-dose Equate Migraine Relief Bufferin Aspirin 325 mg Robaxisal Tablets Deluxe Dental Emergency Kit Enteric Coated Asa Tablets 650mg Advanced Pain Reliever Bayer Headache Family Care Effervescent Antacid and Pain Relief Extra Strenght Headache Relief Quality Choice Effervescent Cold Relief Plus Dg Health Aspirin Madelon Thrulife Extra Strength Headache Relief Entrophen 80mg BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES Effervescent Pain Relief Fast Relief BC Cherry Bio-asa Pain Reliever 2 Bayer PM Berkley and Jensen Migraine Formula Aspirin Coated for Delayed Release Extra Strength Aspirin regular strength 4251 First Aid Kit Ru-21 Hangover Relief Aspirin Pain Relief Green Guard Pain and Ache Relief Genuine First Aid Industrial First Aid ASPIRIN Low Strength Good Neighbor Pharmacy Aspirin Muscle Relaxant and Back Pain Relief Regular Strength Tablets Zee Pain Aid Alka-Seltzer Original Flavor Dristan Capsules Rivacodan 4213 First Aid Kit Asa Tab 325mg Enteric Coated Robaxisal Extra Strength Rx Act headache formula added strength Aspirin Express Pack Robaxisal C 1/2 A.C. & C. 8 mg Kirkland Signature Migraine Relief FIRST AID Contains 101 PIECES HARDCASE Alka Seltzer Plus 2s Blister Pack Dr. Waynes Aspirin Low Dose 692 Tab Dr Pausins Low Dose Chewable Aspirin Cherry Flavor Buffered Aspirin Coricidin D Tab Entrophen 325mg Tablets Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored Dye-Free Aspirin 81 FIRST AID Contains 202 PIECES Lil Drug Store Headache Relief Extra Strength Plus Pharma NSAID 325 mg K-Mart SmartSense First Aid Contains 101 Pieces pain relief back and body EXTRA STRENGTH Asa Ect 325mg Artrifin 24 Caplets Rugby Adult Aspirin 81 mg Low Dose Aspirin M-asa 80 Mg Croquable Extra Strength Midol Extra Strength Pain Relief Euro-asa EC Lowprin A.S.A. (acetylsalicylic Acid) Tab 325mg USP EC-81Aspirin Enteric Coated Alka Seltzer Asa 80 HyVee Health Effervescent Antacid and Pain Relief Bayer Genuine Aspirin Natural Aspirin plus Tart Cherry Dietary Supplement Up and Up Migraine Relief Butalbital, Aspirin, Caffeine and Codeine Phosphate Quality Choice Pain Relief Powder 4217 First Aid Kit Acetylsalicylic Acid Coated Asa 325 Mg Tablets Regular Strength EXCEDRIN MIGRAINE acetaminophen, aspirin (nsaid) and caffeine Alka Seltzer Evt Lowprin 80mg Aspirin Adult low strength Regular Strength Enteric Coated Aspirin Pain Relief Extra Strength Spasmhalt-asa-8 Excedrin Extra Strength Caplets Family Wellness Effervescent Cold Relief Original Alka-Seltzer Plus Cold Sparkling Original PowerFast Fizz Premier Value Antacid and Pain Relief Medicine Dollar General Effervescent Cold Relief Dollar General Headache Powders Care One Aspirin FormuCare Aspirin Berkley and Jensen Aspirin Henry Schein Aspirin Aspergum Orange 325 mg Asatab EC 650mg Aspirin Extra Strength Plus Coryphen 325 Tab Asaphen Alka-Seltzer Plus Cold Formula (Orange Zest) Aspirin 81mg Enteric coated Delayed Release Nervine Tab Adventure Medical Kits 1-4 Person First Aid Excedrin Extra Strength Geltabs Health Mart Regular Strength Enteric Coated Aspirin Quality Choice Effervescent Cold Relief - Orange Aspirin Regular Strength Regular Strength Up and Up Aspirin 25 Person ANSI Asa 80 mg Dolex Forte Duoplavin 4305 First Aid Kit Asa-325 Comprimes Retard Extra Strength Headache Leader Low Dose Aspirin Alka-Seltzer Plus Severe Cold and Flu Aspirin adult low strength Bayer Low Dose Medi First Pain Ache Leader Migraine Relief Teva-tecnal C 1/2 Good Sense Aspirin Alka Seltzer Original Lab Safety Supply Aspirin Ascomp with Codeine Aspirin Adult low dose Enteric Coated Asa 650 mg Pain Reliever Added Strength ACME FIRST AID Contains 404 PIECES 282 Tablets Aspirin Regimen Regular strength aspirin Acetylsalicylic Acid 325mg Tablets USP Bayer AM extra stength Excedrin PM Triple Action Caplets and Excedrin Extra Strength Pain Reliever Bc Cherry WinCo Foods Effervescent Antacid and Pain Relief Ag-asa EC Aspirin Thin coated Medique Products Aspirin K-Mart SmartSense First Aid Contains 303 Pieces Asa 325mg Enteric coated aspirin Regular strength Equate Daily Low-dose Bayer Migraine Formula Pain Stoppers Extra C2 Tab With Codeine Aspirin NSAID Goodys Migraine Relief Nra-asa 80 Mg Croquable Regular Strength Enteric coated aspirin Coated Daily Low-dose Asa Ready America First Aid Outdoor- 107 Pieces Pain Reliever Plus Bufferin Low Dose Buffered Aspirin Unishield Pain Zapper 4250 First Aid Kit Coryphen 325 Codeine 30 Tab Aspirin Plus Stomach Guard Extra Strength ASPIRIN Low Dose Bromo Seltzer Entrophen 650mg Caplet Ect Headache relief Extra Strength Medi-First Aspirin Coachs First Aid Contains 102 Pieces Headache Relief Extra Strength Good Neighbor Pharmacy Headache Relief Family Wellness Migraine Asa Aspirin Arthritis Pain Relief 650 mg Aspirin EC ARC FIRST AID Contains 101 PIECES Hardcase Childrens Low Dose Aspirin MEDI-FIRST Aspirin 7 Select Adult Chewable Aspirin Alka-Seltzer Plus Cold Orange Zest Equate Extra Strength Effervescent Antacid and Pain Relief Adult Aspirin Regimen Headache Relief Alka-Seltzer Plus Night Cold Formula (Lemon) Anacin With Codeine Tab Headache Formula Extra Strength Aspirin and Extended-release Dipyridamole Leader Cardinal Health Aspirin 4333 First Aid Kit 4224 First Aid Kit Apo Asa Tab 325mg Aspirin Extra Strength Asa 975 Tab Chronic Pain/Fever Relief Freds Effervescent Antacid Pain Relief Quality Choice Extra Strength Effervescent Antacid and Pain Relief Geritrex Aspirin A & C Tablets With Codeine 30mg Extra Strength Pain Aid Low dose aspirin 81mg Topcare Headache Relief Plus Pharma NSAID Aspirin Regular Strength Aspirin EC Bayer Back and Body Extra Strength Care One headache relief added strength Signature Care Migraine Relief Alka-Seltzer Plus Cold Sparkling Original Travel Savvy Aspirin 4139 First Aid Kit Chewable Aspirin Adult low dose Best Choice Effervescent Cold Relief Enteric coated aspirin Goodys PM Pain Reliever Health Sense Ecpirin Clopidogrel/acetylsalicylic Acid Zentiva Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Kroger Effervescent Antacid and Pain Relief Pain Free Aspirin and Omeprazole Delayed-release Tab Acetylsalicylic Acid Stomach Protection 325mg Tablets Handy Solutions GENUINE ASPIRIN BAYER 4230 First Aid Kit Aspirin 81 4303 First Aid Kit Asa Tab 325mg Aspirin enteric coated low dose Enteric Coated Asprin Low Dose Medique Medi Seltzer Aspir Low Drug Mart Effervescent Pain Relief 282 Tab Care One migraine relief Pro-aas EC - 80 Chewable Low Dose Solves - aspirin Cherry Acetaminophen, Aspirin, Caffeine DG Health Effervescent Antacid and Pain Relief Walmart Pain Relief Powder Excedrin Extra Strength Pain Reliever Alka-Seltzer Plus Severe Cold Night PowerFast Fizz ARC Emergency Preparedness FIRST AID Contains 202 PIECES Alka-Seltzer Hangover Relief Equate Effervescent Cold Relief Teva-tecnal C 1/4 Muscle and Back Pain Relief With Asa Family Wellness Migraine Relief Jamp-asa Chew Basic Care Headache Relief Smart Sense migraine relief Alka-Seltzer Plus Severe Cold PowerFast Fizz Aspirin Plus Stomach Guard Ext.stgth.caplet Pronal - C1/2 Capsules Aspirin Enteric Coated Caplet 325mg C2 Buffered With Codeine Tab Health Mart Migraine Relief Pain Stoppers Regular Topcare Migraine Formula Rexall Coated Daily Low Dose Asa 292 Tablets Mountain Series Weekender Medical Goodys Cool Orange Fiorinal Sunmark aspirin adult low strength Sunmark Aspirin Adult Low Strength Asa Suppositories 150mg Careone Aspirin Chewable Daily Low Dose Asa Pronal C1/4 Capsules Lowprin 325 ARC FIRST AID Contains 404 PIECES Aspica (Aspirin) Alka-Seltzer Plus Cold and Cough Alka-Seltzer Plus Cold Medicine Sparkling Original Splizz Pain Reliever - Grapefruit-flavored Family Wellness Aspirin Aspirin 81mg Quick Chews Circle K Headache Relief Extra Strength Clopidogrel/acetylsalicylic Acid Mylan Foster and Thrive Migraine Relief Aspirin 81mg Adult Low Dose Aspirin chewable low dose Norgesic Tab Reese Headache Powders Uncoated Aspirin Acetaminophen Aspirin Caffeine Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate Tablets Adult Low Dose Enteric Coated Aspirin Aspirin Night-time Bayer Aspirin Green Guard Tri Buffered Aspirin relief Rapidol Aspirin Display 2x25 Trianal C½ 4346 First Aid Kit Pain Relief PM Topcare Migraine Relief Pain Terminator 2 Severe Acetylsalicylic Acid, Caffeine and 8 Mg Codeine Phosphate Smart Sense Aspirin Equagesic Tablets Sunmark aspirin low dose 4214 First Aid Kit Adult Low Dose Aspirin Enteric Safety Coated ASPIRIN 81 MG Low Dose Muscle and Back Pain Relief With Asa Extra Strength Topcare Headache Formula Good Sense Headache Relief Basic Care Migraine Relief Signature Care Aspririn C-2 Buffered With Codeine Equaline Effervescent Cold Relief Alka-Seltzer Original Excedrin Migraine, TRAVEL BASIX PMS-asa North Aspirin Migraine Formula Halfprin Low Dose Aspirin Safety Coated Healthy Accents headache relief added strength Instantine Tab Synalgos Xpect Pain Away Extra Strength Alka-Seltzer Plus Multi-Symptom Cold Day and Night Pain Reliever Teva-tecnal Dolodol BC Arthritis Pain Relief Added Strength Muscle & Back Pain Asa 325 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 325 mg Arco Pain Tab Aspirin - Children's Size 80mg Aggrenox Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange Rivasa 80 Mg EC Pronal Capsules Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Rexall Aspirin Equaline headache formula added strength Enteric Coated Daily Low Dose Asa 81 mg Axisal-C1/8 Hydrocodone Bitartrate and Aspirin Methoxisal-C 1/8 Percodan-demi Alka-seltzer Original Phenaphen No 4 Cap Unishield Aspirin Orphenadrine Citrate, Aspirin and Caffeine FIRST AID Contains 303 PIECES Yosprala Muscle and Back Pain Relief Extra Strength Ana-dent Enteric Coated Aspirin Regular Strength Adalat XL Plus Aspirin With Stomach Guard Extra Strength - Tab Medi-First Plus Aspirin Asa and Caffeine Aspirin-dipyridamole Aspirin Rapid Relief MEDI-FIRST Tri Buffered Aspirin Aspirin 325mg Medi First Plus Pain Ache Extra Strength Aspirin Asprin Enteric Coated Asa Daily Low Dose Safety Coated Aspirin Aspirin E-C Low Dose Safety Coated Extraprin Good Sense headache formula added strength A.C. & C. 8mg 4142 First Aid Kit Alka Seltzer Originial 1s Blister Pack Chewable Aspirin Low Dose Regular Strength Tri-Buffered Aspirin Exact Coated Daily Low-dose Asa 4215 First Aid Kit Durlaza Aspirin 325 Mg EC Asaphen E.C. 80 mg Alka-Seltzer Plus Severe Cold and Cough PowerFast Fizz Bc Max BioElectro Extra Strength Daytime Pain Relief Alka-Seltzer Plus Cold Formula (Cherry Burst) Crane Safety XS Pain Relief AspirinLow Dose Low Dose 217 Herbopyrine Tab 325mg Fiorinal with Codeine Goodys Amazon Basic Care Migraine Relief A.S.A. With Methocarbamol Night-time Extra Strength Anacin Extra Strength Buffered Aspirin Regular Strength MEDIQUE Tri Buffered Aspirin Norgesic Forte Publix Fast Relief Effervescent Biovanta Trip Action Tart Cherry and Honey A.S.A. Tablets 5gr BP Aspirin 81mg Extra Strength Asa 500mg FIRST AID Contains 303 PIECES HARDCASE HEALTH SENSE Adult Chewable Low Strength Aspirin SohMed Pain Reliever enteric coated aspirin Regular Strength Aspirin Low Dose Sugar Free Enteric Coated Asa Tablets 325mg TopCare Aspirin Calmine Tab Pronal Tablets A.C.& C Tablets Aspirin Stomach Guard Extra Strength 4154 First Aid Kit Alka-Seltzer Plus Cold Day and Night Asa 81 mg Natural Aspirin plus Immune Supporting Dietary Supplement Pain Relief Aspirin Chewable, Low Dose aspirin Regular strength Sound Body Migraine Relief ShopRite Migraine Formula 4032 First Aid Kit Methocarbamol and Aspirin 50 Person ANSI 4232 First Aid Kit HyVee Health Effervescent Cold Relief Dr Pausins Aspirin Extra Pain Relief Sunmark Headache Relief Basic Dental Emergency Kit First Aid Only Aspirin ASPIRIN Regular Strength Alka Seltzer Plus 1s Blister Pack 4228 First Aid Kit Extra Strength Headach Relief Pamprin Max Menstrual Pain Relief Aspirin Low Dose Alka-Seltzer Plus Day Non Drowsy Cold Medicine Citrus Chewable Adult Low Dose Aspirin Exaprin 4244 First Aid Kit A.C. & C 8mg Tab Headache Relief Added Strength 222 Tablets Sunmark Aspirin Viva Asa 325 mg Health Sense Aspirin 81 St. Joseph Safety Coated Aspirin Aspirin Low Dose Safety Coated Meijer Effervescent Cold Relief Alka-seltzer Flavoured - Evt Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg Valumeds Aspirin Muscle and Back Pain Relief Excedrin Menstrual Complete Pain Stopper Extra ARC FIRST AID Contains 303 PIECES Good Neighbor Pharmacy Aspirin Enteric Safety Coated Alka-seltzer Morning Relief Cardiaspirin Protect PHL-asa Pharbest Aspirin 325mg MICRO-COATED ASPIRIN 325 mg GOODYS Extra Strength Headache Mixed Fruit Blast Family Wellness Pain Relief Powder Asa Chewable Tablets Headache Pain Reliever Equaline migraine formula Acetylsalicylic Acid 325mg Tab ShopRite Aspirin Entrophen Ect 975mg Pain Relief Aspirin Low Dose Robaxisal C-1/8 Tablets Lab Safety and Supply Tri Buffered Aspirin Low Dose Miniprin Enteric Safety Coated Oxycodone Hydrochloride and Aspirin Smart Sense Chewable Aspirin Dr Pausins Low Dose Chewable Aspirin Orange Flavor Aspirin Adult Low Dose 4209 First Aid Kit Meijer Effervescent Antacid and Pain Relief Green Guard Extra Strength Pain Relief Basic Care Aspirin Percodan Dr. Juans Santo Remedio PARA LA ACIDEZ Aspirin, Caffeine, and Dihydrocodeine Bitartrate Orphenadrine Citrate Aspirin Caffeine Berkley and Jensen Migraine Relief Safety Coated Aspirin 81 mg Low Dose MYGRIN Nighttime Asa-650 Comprimes Retard Neo Tigol Tab Alka-Seltzer 4221 First Aid Kit 4229 First Aid Kit Excedrin PM Triple Action Caplets Sunmark Aspirin Regular Strength Jamp-asa EC Aspirin Enteric Coated Aspirin regular strength Vazalore 4342 First Aid Kit PMS-pharnal-C1/2 Capsules Phenaphen No.4 Cap 365 Everyday Value Aspirin 4211 First Aid Kit Excedrin Migraine 4248 First Aid Kit Aspirin and Dipyridamole Extended Release Alka-Seltzer Plus Severe Cold Powerfast Fizz Night EXTRA STRENGTH Headache Relief geltabs Methoxisal-C 1/4 ARC FIRST AID Contains 101 PIECES Physicians Care Extra Strength Pain Reliever Up and Up aspirin GENUINE FIRST AID Emergency Preparedness Contains 167 Pieces Extra Strength Headache, Caseys 4good Miniprin Methoxisal Bayer Aspirin Regimen enteric coated Sunmark Adult Aspirin Aramark Pain-Free Extra Strength Entrophen Ect 500mg Safety Coated Low Dose Aspirin Effervescent Pain Relief Kirkland Signature Migraine Headache Relief Aspergum 325 Mg (cherry) Ache and Pain Relief to Go Aspir-81 Low Dose Aspirin 81 mg Safety Coated Medique Pain Off 4340 First Aid Kit 292 Tab Zee-Seltzer Antacid and Pain Reliever Dg Health Headache Relief Aspirin Enteric Coated Safety Coated Aspirin 325 mg Regular Strength MooreBrand Aspirin Rivasa 80mg Croquable - Tab Cove Migraine Relief Methoxisal Extra Strength Up and Up Antacid and Pain Relief Pro-aas - 80 (croquable) WinCo Foods Effervescent Cold Relief Leader Headache Formula Added Strength Headache Relief to Go Thompson XS Pain Ache Aspirin 81 mg Fiorinal-C 1/2 Kroger Value Aspirin Aspirin and Dipyridamole Acetaminophen, Aspirin and Codeine Phosphate Ac&c Tablets Bufferin Arthritis Ascriptin Maximum Strength Buffered Aspirin Anacin Pal-pravastatin-asa Rivasa Fc A.S.A. Enteric Coated Tab 650mg Walgreens Pain Relief Powder Pain Aid Aspirin Tablets 325mg Crane Safety Aspirin Antidol Tablets Formu Care pain reliever added strength Asaphen Plus 325 10 Person ANSI Aspirin Granules PMS-pharnal Capsules Adult Low Strength Aspirin Aspirin 81 mg Enteric Coated Care One Original Antacid and Pain Relief Asa Ect 600mg Lil Drug Store Aspirin 325 Vanquish Regular Strength Asa Enteric Coated A.S.a (caplet) Bayer Enteric Safety Coated Aspirin Effervescent Orange Cold Relief 4365 First Aid Kit Asadol 650mg BAYER 500 mg Medi First Pain Relief Novo-propoxyn Compound Cap Praxis Asa EC 81 Mg Daily Low Dose Advanced Aspirin Bayer Advanced Aspirin Regular Strength Low Dose Aspirin Coryphen 650 Codeine 30 Tab Fiorinal-C 1/4 Anacin Extra Strength Tablet Anacin Tablet Extra Strength Midol Relief Rx Act Aspirin Aspirin Low Dose Chewable Orange Dg Health Migraine Relief Fairfield Health Products Extra Strength Asa Tablets USP 325 mg Smart Sense Migraine Formula Equate Aspirin Aramark Aspirin Midol Regular Physicians Care Aspirin Trianal C¼ BioElectro Day Butalbital, Aspirin and Caffeine Astrin 5gr Enteric Coated Asa 325 mg Instantine - Tablets Chewable Aspirin Super Extra Strength Aspirin Backache Market Basket Effervescent Antacid and Pain Relief A & C Tablets With Codeine 15mg Orphengesic Forte Only for Headache Arthriten Inflammatory Pain Formula Aspirin 5 grain Pain Relief Fast Relief Equaline Effervescent Antacid and Pain Relief Pain Relief Aspirin Unishield Pain Ache St. Joseph Low Dose Aspirin Ecotrin Leader Aspirin C2 Buffered Tab Top Value Effervescent Pain Relief Alka-seltzer Flavoured Norgesic Alka-Seltzer Plus Acetylsalicylic Acid Extra Strength 500mg Tablets USP Family Wellness Effervescent Antacid and Pain Relief Splizz Pain Reliever - Orange-flavored Euro Asa 7 Select Aspirin Acetaminophen Aspirin and Caffeine Nervine Medi First Plus Aspirin Lowprin 325 Chewable Tablet Anacin AF Up and Up Chewable Aspirin Equaline aspirin adult low dose Aspirin Safety Coated Enteric, Regular Strength Health Mart Aspirin Norgesic Forte Tab Stanback Walgreens Effervescent Cold Relief Plus BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE Adults Low Strength Aspirin Fiorinal Tab Pain Stoppers EX Smart Health Aspirin Regular Strength Vida Mia Pain Relief Walgreens Effervescent Pain Relief Ecotrin Regular Strength Aspi-Cor Aspirin Stomach Guard Regular Strength Low Dose Aspirin Chewable Muscle & Back Pain Relief Extra Strength A.S.A. Aspirin to Go Pharbest Regular Strength Aspirin Exaprin-AC St. Joseph Chewable Aspirin Phenaphen No.3 Cap Phenaphen No 3 Cap Aspirin Chewable, Low Dose Asa 500 Mg Tablets Extra Strength Coraspirina 81 mg Tabletas con cubierta enterica Dolomine 37 Neutra-seltzer Arthriten Max Soma Oxycodone and Aspirin Alka Seltzer Plus Cold Aspirin Safety Coated Adult Low Dose Bayer Plus Extra Strength Excinol Migraine (Acetaminophen) FIRST AID Contains 1000 PIECES Excedrin Back and Body 4304 First Aid Kit Aspirin Enteric Coated, Regular Strength Aspirin Chewable Low Dose Alka-Seltzer Plus Day and Night Cold A.S.A. 325 Mg Tablet Chewable Low Dose Aspirin Best Choice Effervescent Antacid Pain Relief Carisoprodol and Aspirin Citramon Enteric Coated A.S.a Sedal3x Uline Aspirin Tylo Migraine (Acetaminophen) Alka-Seltzer Extra Strength Acetaminophen 250mg Aspirin 250mg Caffeine 65mg Extra Strength Back and Body Muscle Relaxant and Back Pain Relief Extra Strength Tablets Pain Reliever Extra Strength Genuine Aspirin Family Wellness Effervescent Cold Relief Orange 4395 First Aid Kit 4389 First Aid Kit Aspirin With Stomach Guard CAREALL Aspirin Regular Strength Aspirin Alka-Seltzer Plus Multi-Symptom Cold and Cough Effervescent Cold Relief - Orange Bi Electro Extra Strength Adult Aspirin Regimen Low Dose Good Sense Effervescent Cold Relief Goodys Cool Orange Headache Headache Tab 300mg Acetylsalicylic Acid Tab 300mg Asa Extra Strength Tab 500mg A.S.A. Enteric Coated Tab 325mg Aspirin Chewable Tablets 325mg Lo-asa 80mg Chewable - Tab Sunmark migraine relief Darvon N Compound Pulvule 405 First Aid Direct Aspirin dihydrocodeine bitartrate and aspirin and caffeine DC Good Sense Effervescent Antacid and Pain Relief Direct Safety Aspirin Ag-asa Chew Alka-Seltzer XTRA STRENGTH Alka-Seltzer Plus Cold and Cough Formula Ac and C Tab 1/8gr Aspirin Low Strength, Enteric Auto 157 4240 First Aid Kit Jamp-asa 81mg EC CVS Health Antacid and Pain Reliever Enteric Coated A.S.A. Excedrin PM Triple Action Caplets and Excedrin Tension Headache Phenaphen No 2 Cap ARC FIRST AID Emergency Preparedness Contains 167 PIECES Biovanta Double Action Leader Extra Strength Effervescent Antacid and Pain Reliever Anacin Extra Strength Caplets Teva-oxycodan Anacin ES Only For FIRST AID MEDICINE Dg Health Headache Relief Added Strength Low Dose Aspirin Enteric Safety Coated Protection Topcare Aspirin 4196 First Aid Kit 4356 First Aid Kit Health Mart Adult Aspirin Acetylsalicylic Acid Tab 325mg Clopidogrel Kit GFA First Aid 75 Person Metal Case Good Neighbor Pharmacy Migraine Relief Easy Care First Aid Kit - Comprehensive Pain Free Plus Sunmark Migraine Relief ULINE Aspirin Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Aspirin enteric safety coated Top Value Effervescent Cold Relief Excedrin Migraine Geltabs Signature Care Aspirin Relief Asa Extra Strength Adventure Medical Kits 1-2 Person National Ski Patrol First Aid Aspirin Extra Strength With Stomach Guard Aspirin Low Dose Enteric Coated Extra Strength Headache, Circle K Asa EC Bc Methoxisal-C 1/2 Novasen Bayer Fast Release Childrens Aspirin Dry Socket Paste Rapidol Aspirin Aspirin 81 mg Low Dose Handy Solutions Headache Pain Relief 4291 First Aid Kit Equate Effervescent Antacid and Pain Relief PMS-pharnal Tablets Coricidin Tab Asa 80mg Medpurine Adult Chewable Aspirin Excedrin Extra Strength Headache Pain Terminator Robaxisal C 1/4 Harris Teeter Migraine Relief Anacin Caplets Effervescent Cold Relief GFA First Aid Kit Essentials - 33 Pieces Rite Aid Antacid and Pain Relief Genuine Bayer Aspirin 7 Select Migraine Formula Endodan Carisoprodol, Aspirin and Codeine Phosphate Migraine Relief Bayer Advanced Aspirin Extra Strength Asa Acetylsalicylic Acid Enteric Coated Low Dose Aspirin Butalbital, Aspirin, and Caffeine Bufferin Extra -strength McKesson Aspirin Entrophen 325mg Caplets Alka Seltzer Flavoured Good Sense Migraine Formula Xpect Pain Away Rivasa 81 Mg EC Aspirin Low Strength Adult CVS Health Extra Strength Antacid and Pain Reliever Headache Relief PM Tabcin 500 Goodys Back and Body Pain Excedrin Extra Strength Fasprin Pravigard Pac Acetylsalicylic Acid Tab 325mg BP PhysiciansCare Extra Stregth Pain Reliever Conney Aspirin Medi First Plus Tri Buffered Aspirin PHL-asa E.C. Equagesic Aspirin Safety coated Top Value Effervescent Cold Relief - Orange Nezger Tab Low Dose Aspirin Enteric Safety-Coated ENTERIC COATED ASPIRIN Regular Strength Moore Medical Aspirin Painex Tab 0.5gr Adult Low Dose Aspirin Enteric Coated Aspirin - Children's Size - Tablets GOODYS Hangover Medique at Home Aspirin Acido Acetilsalicilico With enteric coat Quality Choice Effervescent Antacid and Pain Relief 4227 First Aid Kit Bufferin Regular Strength Pain Relief Enteric Aspirin Excedrin Migraine, CVP HEALTH Extra Strength Muscle & Back Pain Asa 500 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 500 mg Headache Formula Added Strength Butalbital, aspirin, and caffeine Alka-Seltzer Lemon Lime Asa Extra Strength Caplet 500mg Best Choice Pain Relief Powder Coryphen 650 Tab Asa EC 80 Effervescent Antacid and Pain Relief Asatab 80 Mg Chewable Tablets Uricalm Intensive Smart Sense Effervescent Antacid and Pain Relief Trianal Tablet ARC FIRST AID Contains 1000 PIECES Asatab EC 325mg Aspirin 81 MG Entrophen Ect 650mg Health Mart Migraine Formula C T Acetylsalicylic Acid Codeine and Caf Tab Regular Strength Pain Relief 4388 First Aid Kit Bayer Headache Relief Butalbital, Aspirin, Caffeine, and Codeine Phosphate Extra Strength Muscle & Back Pain Relief With Asa Biovanta Trip Action Lemon and Honey Good Sense Aspirin Enteric Safety Coated Aspirin Chewable Tablets Right Remedies Aspirin Low Dose 81 mg Sns-asa EC Pain Aid ESF CVS All Purpose First Aid Kit Aspirin Delayed Release Aspirin 81mg Enteric coated Low Strength Aspirin Regimen BackAid Inflammatory Pain Formula Caring Mill Aspirin Excedrin Extra Strength and Excedrin Tension Headache Leader migraine formula Tri-Buffered Aspirin Regular Strength PMS-pharnal-C 1/4 Capsules Rapid Comfort Aspirin ALKA SELTZER PLUS Cold Day and Night Effervescent Low Strength Chewable Aspirin St. Joseph Chewable Low Dose Aspirin Euro Asa 325mg Chewable Tablet A.S.A. 80mg Acetylsalicylic Acid Tablets Tri-buffered Asa Tab Asa, Caffeine & 8mg Codeine Phosphate PMS-asa EC Bubbles R Better Effervescent Cold Relief Aspirin Chewable Tablets - 325mg Zee Aspirin Caring Mill Migraine Relief Aspirin Backache 4355 First Aid Kit 4387 First Aid Kit 4313 First Aid Kit Equaline Aspirin Aspirin and Extended-Release Dipyridamole Good Neighbor Pharmacy aspirin orange flavor chewable Acetaminophen, Aspirin and Caffeine Equate Aspirin Chewable Aspirin Coated for Delayed Release Regular Strength Aspirin Enteric Coated Low Dose Aspirin Pain reliver Extra Strength Aspirin Backache Asa Suppositories 650mg Blowfish Goodys Extra Strength Flanax Aspirin Pain Reliever Asa-caffeine-codeine 4134 First Aid Kit Circle K Aspirin 325 4249 First Aid Kit Ascriptin Regular Strength Buffered Aspirin Extra Strength Headache Relief Dr Pausins Low Dose Aspirin Aspirin Chewable Aspirin Plus Stomach Guard Tab ARC FIRST AID Contains 303 PIECES HARDCASE Pain Relief Maximum Strength Migralex Dr. Mauskop Aspirin Adult Low Strength Taro-dipyridamole/ Asa 4332 First Aid Kit Aspirin Enteric Safety Coated First Aid Direct Chewable Aspirin Good Sense aspirin Low Dose Chewable Aspirin Butalbital Compound Rugby Aspirin Back and Body Extra Strength TopCare Effervescent Antacid and Pain Relief 4216 First Aid Kit Aspirin Migraine Headache, Circle K 692 Tablet Value Pharma Aspirin Pain Reliever Coricidin Nd Tab Alka-Seltzer Plus Severe Cold PowerFast Fizz Orange Zest Biovanta Trip Action Green Apple and Honey Enteric Aspirin Regular Strength FIRST AID Contains 404 PIECES Aspirin Regular Strength Asa Ect 650mg Adventure Medical Kits 1-2 Person First Aid Smart Sense Effervescent Cold Relief Assured Aspirin CVS Health Medication and Topical Refill Pouch Acetylsalicylic Acid Extra Strength Stomach Protection 500mg Caplets Effervescent Pain Relief Fast Relief Fast Relief Aspirin Tab 325mg USP Aramark Pain Free BAYER Aspirin Extra Strength Caplets Coated Aspirin Adult Low Dose Aspirin Adult Low strength Aspirin Aspirin Coated Caplets 325 mg Entrophen Chewable Aspirin Coated Caplets 500mg Coated Aspirin - Ect 80mg Added Strength Pain Reliever HEB Extra Strength Effervescent Antacid and Pain Relief Adult Low Dose Alka-Seltzer Plus Night Cold Medicine Acetylsalicylic Acid A.S.A. Tablets 325mg Aspirin Low Dose Chewable Healthy Accents Aspirin Circle K Headache Relief FIRST AID Contains 101 PIECES Asa Daily Low Dose Painex Tab 0.25gr Medi First Plus Pain Zapper Picot Plus Effervescent 4225 First Aid Kit GenCare Headache Relief NobleAid PAIN RELIEVER Phenaphen No.2 Cap Kroger Effervescent Cold Relief Alka-Seltzer Plus Multi-Symptom Cold Night Trianal Capsules Aspirin 50 CT Alka-Seltzer Plus Cold Night
Indication	Pain, fever, and inflammation Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label]. The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label]. Other indications ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include: Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label]. Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label]. For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label]. For the prevention of thromboembolism after hip replacement surgery [FDA label]. For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label]. Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label]. Important note regarding use of the extended-release formulation [F4405] In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
Categories	Acids, Carbocyclic Agents causing angioedema Agents causing hyperkalemia Agents that produce hypertension Alimentary Tract and Metabolism Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antiinflammatory and Antirheumatic Products Antiplatelet agents Antipyretics Benzene Derivatives Blood and Blood Forming Organs Cardiovascular Agents Cyclooxygenase Inhibitors Cytochrome P-450 CYP2C19 Inducers Cytochrome P-450 CYP2C19 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Decreased Platelet Aggregation Decreased Prostaglandin Production Drugs that are Mainly Renally Excreted Hematologic Agents Hydroxybenzoates Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS OAT1/SLC22A6 inhibitors OAT3/SLC22A8 Inhibitors P-glycoprotein inducers P-glycoprotein substrates Peripheral Nervous System Agents Platelet Aggregation Inhibitors Excl. Heparin Salicylates Salicylic Acid and Derivatives Sensory System Agents Stomatological Preparations UGT1A6 substrate
ATC-Code	B01AC06 C07FX04 C10BX04 M01BA03 C10BX02 N02BA71 B01AC56 N02AJ07 N02AJ02 N02BA01 B01AF51 C10BX05 N02BA51 A01AD05 C10BX01 C07FX03 N02AJ18 C10BX12 C10BX08 C10BX06 C07FX02
CAS number	50-78-2

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown	inhibitor
3-hydroxy-3-methylglutaryl-coenzyme A reductase	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYEC...	unknown	inhibitor
Prostaglandin G/H synthase 2	MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFY...	unknown	inhibitor
Aldo-keto reductase family 1 member C1	MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHID...	unknown	inhibitor
5'-AMP-activated protein kinase	MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTG...	unknown	activator
Endothelin-1 receptor	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVT...	unknown	inhibitor
Cellular tumor antigen p53	MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDI...	unknown	inducer
Endoplasmic reticulum chaperone BiP	MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRV...	unknown	inhibitor,binder
Ribosomal protein S6 kinase alpha-3	MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEI...	unknown	inhibitor
NF-kappa-B inhibitor alpha	MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQ...	unknown	inhibitor
Tumor necrosis factor-inducible gene 6 protein	MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLT...	unknown	inhibitor,downregulator
Caspase-1	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATV...	unknown	inhibitor,downregulator
Caspase-3	MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIII...	unknown	inhibitor,downregulator
Inhibitor of nuclear factor kappa-B kinase subunit beta	MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQEL...	unknown
Extracellular signal-regulated kinase (ERK)	MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR...	unknown
G1/S-specific cyclin-D1	MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQK...	unknown	downregulator
Myc proto-oncogene protein	MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQ...	unknown	downregulator
Proliferating cell nuclear antigen	MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQL...	unknown	downregulator
Cyclin A	-	unknown	downregulator
Sialidase-1	MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAEND...	unknown	inhibitor
Cytochrome P450 2C19	MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDV...	unknown	inducer
Cytochrome P450 2C9	MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...	unknown	substrate
UDP-glucuronosyltransferase 1-6	MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLS...	unknown	substrate
Arylamine N-acetyltransferase 2	MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMEL...	unknown	substrate
Solute carrier family 22 member 6	MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCR...	unknown	inhibitor
ATP-dependent translocase ABCB1	MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLY...	unknown	substrate,inducer,modulator
Organic anion transporter 3	MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCR...	unknown	inhibitor
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL25
PubChem	2244
ChEMBL	CHEMBL25
ChEBI	CHEBI:15365
CCDC/CSD	ACSALA21, ACSALA23, ACSALA14, TAZRAO01, DIFQAK, ACSALA20, DIPJAQ, VUGMIT, ACSALA26, ACSALA15, ARIFOX, KEWNOQ, ACSALA17, ACSALA25, ACSALA01, ACSALA19, SIBYUA, ACSALA27, TAZRAO, HUNJEH, ACSALA28, SIBYUA01, ACSALA02, ACSALA08, ACSALA07, ACSALA05, ACSALA03, ACSALA04, ACSALA06, ACSALA11, ACSALA09, SIBYUA02, ACSALA29, GARYEH, HAPCOU
COD	7126911, 1515582, 1515581, 2104857, 1516479, 1516481, 1516480, 4100978, 7247818, 7247819, 7050897, 7050898, 7050899, 7050900, 7050901, 7050902, 7050903