AIN

2-(ACETYLOXY)BENZOIC ACID

Created:	2004-04-08
Last modified:	2020-05-26

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8 entries where AIN is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	21
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	6

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Chemical Component Summary
Name	2-(ACETYLOXY)BENZOIC ACID
Synonyms	ACETYLSALICYLIC ACID; ASPIRIN
Systematic Name (OpenEye OEToolkits)	2-acetyloxybenzoic acid
Formula	C₉ H₈ O₄
Molecular Weight	180.157
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(Oc1ccccc1C(=O)O)C
SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
Canonical SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
InChI	InChI	1.03	InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChIKey	InChI	1.03	BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00945
Name	Acetylsalicylic acid
Groups	approved vet_approved
Description	Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Synonyms	Azetylsalizylsäure ácido acetilsalicílico Lysine acetylsalicylate acide 2-(acétyloxy)benzoïque Polopiryna Acide acétylsalicylique O-acetylsalicylic acid 2-Acetoxybenzenecarboxylic acid 2-Acetoxybenzoic acid Acidum acetylsalicylicum Acetylsalicylsäure o-carboxyphenyl acetate Acetylsalicylate o-acetoxybenzoic acid Aspirin Acetylsalicylic acid ASA Aspirina Salicylic acid acetate
Brand Names	Pain Free ARC FIRST AID Contains 101 PIECES Hardcase Solves - aspirin Cherry 4216 First Aid Kit Euro Asa 325mg Chewable Tablet Pamprin Max Menstrual Pain Relief Bayer Back and Body Extra Strength Asa Bayer Advanced Aspirin Extra Strength Enteric Aspirin Biovanta Trip Action Lemon and Honey Excedrin Extra Strength Caplets Nervine Tab CVS Health Antacid and Pain Reliever Coated Aspirin Low-dose Aspirin Chewable Tablets 325mg Low dose Aspirin Extra Strength Headach Relief Pro-aas EC Clopidogrel/acetylsalicylic Acid Mylan Acetylsalicylic Acid Extra Strength Stomach Protection 500mg Caplets Enteric coated aspirin Regular strength Excedrin Extra Strength Headache Methoxisal-C 1/2 4215 First Aid Kit Low dose aspirin 81mg Asatab 80 Mg Chewable Tablets Good Neighbor Pharmacy Migraine Relief 25 Person ANSI Goodys Extra Strength Rite Aid Antacid and Pain Relief Ascriptin Maximum Strength Buffered Aspirin ASPIRIN 81 MG Low Dose Alka-Seltzer Plus BioElectro Day Lowprin 325 Chewable Tablet Pain Reliever Extra Strength Aspirin 5 grain Asa Daily Low Dose Fairfield Health Products Extra Strength PMS-asa EC CVS Health Extra Strength Antacid and Pain Reliever Asa-caffeine-codeine Dg Health Headache Relief FIRST AID Contains 303 PIECES HARDCASE Lab Safety and Supply Tri Buffered Aspirin Painex Tab 0.25gr Only for Headache Lowprin 325 Smart Sense Effervescent Antacid and Pain Relief Smart Sense Aspirin Alka-Seltzer Plus Severe Cold and Cough PowerFast Fizz Adult Low Dose Aspirin Enteric Coated Aspirin 325 Robaxisal Tablets 4355 First Aid Kit Asatab EC 650mg Aspirin Enteric Coated Low Dose ConRx pain Reliever Endodan Excedrin Menstrual Complete Extra Strength Aspirin Alka-Seltzer Plus Night Cold Medicine Aspirin-dipyridamole AspirinLow Dose Low Dose Pronal Capsules Medi First Plus Pain Zapper Aspir Low Aspirin 325 Mg EC Aspirin Adult Low Dose First Aid Direct Aspirin Anacin Tablet Viva Asa 325 mg Muscle and Back Pain Relief With Asa Extra Strength FIRST AID Contains 202 PIECES M-asa 80 Mg Croquable CVS All Purpose First Aid Kit Extra Strength Pain Reliever Euro-asa EC Aspirin 81mg Adult Low Dose Aspirin Plus Stomach Guard Extra Strength Pain Aid Bufferin Low Dose Buffered Aspirin Alka Seltzer Evt Dr Pausins Low Dose Aspirin 4214 First Aid Kit GFA First Aid 75 Person Metal Case Aspirin Low Strength Adult 282 Mep Tab 4246 First Aid Kit Robaxisal C 1/4 Care One Original Antacid and Pain Relief Adventure Medical Kits 1-2 Person First Aid Lil Drug Store Aspirin 325 PMS-pharnal-C1/2 Capsules Tri-Buffered Aspirin Aspirin Extra Strength Lo-asa 80mg Chewable - Tab Meijer Effervescent Cold Relief 10 Person ANSI Bc Cherry Super Extra Strength Aspirin Backache Health Mart Aspirin Alka-Seltzer Plus Severe Cold and Flu Aspirin 81 Alka Seltzer Aspirin Safety coated Zee Pain Aid Anacin Extra Strength Caplets Asaphen Plus 325 Midol Regular Henry Schein Aspirin Acido Acetilsalicilico With enteric coat Deluxe Dental Emergency Kit 4376 First Aid Kit EXTRA STRENGTH Headache Relief geltabs 4250 First Aid Kit Rx Act Aspirin Enteric Coated A.S.A. 4230 First Aid Kit Aramark Pain Free Alka-seltzer Morning Relief C2 Buffered With Codeine Tab 4227 First Aid Kit Alka-Seltzer Plus Day and Night Cold Equagesic Tablets Aspirin Stomach Guard Extra Strength Anacin Family Wellness Aspirin Trianal C¼ Low Dose Aspirin Enteric Safety-Coated Muscle & Back Pain Asa 325 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 325 mg Aspirin - Children's Size 80mg Aspirin Safety Coated Adult Low Dose Axisal-C1/8 Asa-650 Comprimes Retard FIRST AID Contains 303 PIECES Market Basket Effervescent Antacid and Pain Relief Berkley and Jensen Aspirin Family Wellness Pain Relief Powder A.S.A. With Methocarbamol Night-time Extra Strength Novo-propoxyn Compound Cap Tri-Buffered Aspirin Regular Strength Zee-Seltzer Antacid and Pain Reliever K-Mart SmartSense First Aid Contains 101 Pieces Good Sense aspirin Alka-Seltzer Plus Cold and Cough Plus Pharma NSAID Aspirin Topcare Headache Formula Extra Strenght Headache Relief Enteric Coated Asa Daily Low Dose Sns-asa EC Biovanta Double Action Splizz Pain Reliever - Grapefruit-flavored Alka-Seltzer Plus Cold Sparkling Original PowerFast Fizz Aspirin Low Dose Chewable Orange Aspirin With Stomach Guard Green Guard Extra Strength Pain Relief Extra Pain Reliever Citramon Alka-Seltzer Plus Cold Medicine Sparkling Original A.C. & C. 8mg Nra-asa 80 Mg Croquable Alka-Seltzer Plus Severe Cold Night PowerFast Fizz 4388 First Aid Kit pain relief back and body EXTRA STRENGTH A.S.A. 80mg Acetylsalicylic Acid Tablets Thompson XS Pain Ache Valumeds Aspirin Leader Aspirin Headache Tab 300mg Equaline Aspirin Novo Ac and C 8mg Tab Entrophen 325mg Caplets Aspica (Aspirin) Coated Aspirin - Ect 80mg Dr Pausins Aspirin DG Health Effervescent Antacid and Pain Relief A.C. & C. 8 mg Bc Enteric Aspirin Regular Strength Best Choice Effervescent Antacid Pain Relief Leader migraine formula MEDI-FIRST Aspirin Signature Care Aspririn Sunmark Aspirin Adult Low Strength PMS-pharnal Capsules ACME FIRST AID Contains 404 PIECES Walgreens Pain Relief Powder C-2 Buffered With Codeine Seedalmerk 4332 First Aid Kit A.C. & C 8mg Tab dihydrocodeine bitartrate and aspirin and caffeine DC Pain Reliever 2 Pain Stoppers Regular Adventure Medical Kits 1-4 Person First Aid 4304 First Aid Kit Healthy Accents Aspirin Aspirin 81 mg Low Dose Alka-Seltzer Plus Night Cold Formula (Lemon) Alka-Seltzer Plus Cold Orange Zest Butalbital, Aspirin and Caffeine Childrens Low Dose Aspirin Safety Coated Aspirin 81 mg Low Dose Bayer Womens 4346 First Aid Kit Acetaminophen, Aspirin and Codeine Phosphate Adult Low Dose Aspirin Enteric Safety Coated Xpect Pain Away Extra Strength HyVee Health Effervescent Cold Relief Aspir-81 Methoxisal Extra Strength Medique at Home Aspirin 282 Tablets 292 Tablets Safety Coated Aspirin 325 mg Regular Strength Rivacodan Dr. Waynes Aspirin Low Dose Childrens Aspirin Acetylsalicylic Acid Extra Strength 500mg Tablets USP Handy Solutions GENUINE ASPIRIN BAYER Jamp-asa Chew Asadol 325mg Medi First Pain Relief Low Dose Aspirin Enteric Safety Coated Asa Suppositories 150mg Entrophen Chewable HyVee Health Effervescent Antacid and Pain Relief Careone Aspirin FIRST AID Contains 101 PIECES Rivasa 81 Mg EC 4389 First Aid Kit Alka-Seltzer Plus Cold Night Conney Aspirin Amazon Basic Care Migraine Relief Aspirin Adult low strength Aspirin Safety Coated Excedrin PM Triple Action Caplets and Excedrin Extra Strength Pain Reliever Headache Relief 4305 First Aid Kit 81 mg Low Dose Aspirin Aspirin Low Dose Safety Coated Aspirin Crane Safety XS Pain Relief Enteric Coated Aspirin Low Dose Aspirin 81 mg Safety Coated Sunmark Aspirin Regular Strength Acetylsalicylic Acid A.S.A. Tablets 325mg Alka-Seltzer Plus Multi-Symptom Cold and Cough Fiorinal-C 1/4 Lowprin 80mg Aspirin Thin coated Neutra-seltzer Foster and Thrive Migraine Relief Topcare Aspirin Genuine Aspirin Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Aspirin With Stomach Guard Extra Strength - Tab Caring Mill Migraine Relief Excinol Migraine (Acetaminophen) Coryphen 325 Codeine 30 Tab Entrophen 650mg Caplet Ect Critical Care Aspirin to Go PMS-pharnal-C 1/4 Capsules Adalat XL Plus Bi Electro Extra Strength Caring Mill Aspirin Robaxisal C 1/2 Asa 81 mg Asaphen EC Effervescent Antacid and Pain Relief Norgesic Tab Robaxisal C-1/8 Tablets A.S.A. Enteric Coated Tab 325mg Oxycodone and Aspirin Synalgos Robaxisal Caplets 692 Tablet Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange 4248 First Aid Kit Good Neighbor Pharmacy Headache Relief Muscle & Back Pain Relief Extra Strength Orphenadrine Citrate Aspirin Caffeine Rx Act headache formula added strength Aspirin Coated Caplets 500mg SohMed Pain Reliever Percodan-demi Aspirin 81mg Enteric coated Low Strength Aspirin Regimen Kroger Effervescent Cold Relief Pain Terminator Adult Aspirin Regimen Excedrin Extra Strength Pain Reliever Buffered Aspirin Regular Strength Equate Extra Strength Effervescent Antacid and Pain Relief Ecotrin Dolomine 37 Arthriten Max Enteric Coated A.S.a (caplet) Aspirin Coated for Delayed Release Regular Strength Acetylsalicylic Acid Stomach Protection 325mg Tablets Phenaphen No.2 Cap Extra Strength Pain Aid 4032 First Aid Kit Auto 157 Equate Effervescent Cold Relief Equate Aspirin Chewable Fiorinal Tab Alka-seltzer Flavoured - Evt Asa Chewable Tablets Instantine - Tablets Medi First Pain Ache Good Neighbor Pharmacy Aspirin Leader Effervescent Antacid and Pain Relief Norgesic Forte Tab Aspirin regular strength 4395 First Aid Kit C2 Tab With Codeine Topcare Migraine Formula Acetaminophen, Aspirin, Caffeine Kroger Value Aspirin Dolex Forte PHL-asa E.C. Madelon Ag-asa Chew Coated Aspirin Leader Cardinal Health Aspirin Aspirin Low Dose Chewable Alka-Seltzer Original Flavor Signature Care Migraine Relief Health Sense Ecpirin Advanced Aspirin Aspirin Regular Strength Asadol 650mg ARC FIRST AID Contains 303 PIECES HARDCASE Enteric Safety Coated Aspirin HEALTH SENSE Adult Chewable Low Strength Aspirin Regular Strength Tri-Buffered Aspirin Pro-aas - 80 (croquable) Artrifin 24 Caplets Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg Alka-Seltzer Original Good Sense Effervescent Antacid and Pain Relief Alka Seltzer Plus 2s Blister Pack Anacin AF GENUINE FIRST AID Emergency Preparedness Contains 167 PIECES HARDCASE Enteric Coated Daily Low Dose Asa 81 mg Bayer AM extra stength Aspirin 81mg Enteric coated Delayed Release Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate Tablets 4249 First Aid Kit Pain Stopper Extra Aspirin Delayed Release Extra Strength Headache, Caseys 4good Added Strength Pain Reliever Aspirin and Extended-release Dipyridamole Equaline Effervescent Antacid and Pain Relief Ecotrin Regular Strength ARC FIRST AID Contains 303 PIECES ENTERIC COATED ASPIRIN Regular Strength Euro Asa Adult Low Dose Aspirin Ag-asa EC MEDIQUE Aspirin Muscle and Back Pain Relief Extra Strength Pro-aas EC - 80 Aspirin Enteric Care One Aspirin Phenaphen No 2 Cap BC Cherry Astrin 5gr 4139 First Aid Kit Pain Relief Fast Relief Pain Relief Added Strength Butalbital, Aspirin, Caffeine, and Codeine Phosphate Arthriten Inflammatory Pain Formula Aspirin Extra Strength Plus Aspirin adult low strength First Aid Only Aspirin Medi-First Plus Aspirin Unishield Pain Zapper 4356 First Aid Kit Ac&c Tablets Goodys Back and Body Pain Fasprin 7 Select Aspirin Lowprin Enteric Coated Asa 325 mg Effervescent Orange Cold Relief Aspirin Regimen 4228 First Aid Kit Coricidin Nd Tab Signature Care Aspirin Phenaphen No 3 Cap Low Dose Aspirin Chewable 222 Tablets Mountain Series Weekender Medical Dry Socket Paste aspirin Regular strength WinCo Foods Effervescent Antacid and Pain Relief Aspirin A & C Tablets With Codeine 15mg Regular strength aspirin Dg Health Migraine Relief Excedrin Migraine Asa Tab 325mg Enteric Coated Asa 80mg Family Wellness Effervescent Antacid and Pain Relief 4134 First Aid Kit Enteric Coated Asa 650 mg Headache Relief Added Strength EXCEDRIN MIGRAINE acetaminophen, aspirin (nsaid) and caffeine Extra Strength Muscle & Back Pain Asa 500 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 500 mg Circle K Aspirin 325 Acetylsalicylic Acid Tab 325mg BP Coraspirina 81 mg Tabletas con cubierta enterica Aspirin Chewable Low Dose Up and Up aspirin K-Mart SmartSense First Aid Contains 303 Pieces Healthy Accents headache relief added strength Plus Pharma NSAID 325 mg Unishield Pain Ache Bromo Seltzer Effervescent Pain Relief Fast Relief Fast Relief Extra Strength Midol Relief Family Wellness Effervescent Cold Relief Original 4221 First Aid Kit Aspirin E-C Low Dose Safety Coated Vida Mia Pain Relief Lab Safety Supply Aspirin Medique Pain Off Enteric Coated Low Dose Aspirin Genuine Bayer Aspirin Alka-seltzer Flavoured Dollar General Headache Powders Asa 325mg Regular Strength Aspirin Asa EC 80 Muscle and Back Pain Relief Extra Strength Asa 500mg ARC FIRST AID Emergency Preparedness Contains 167 PIECES Anacin Extra Strength Tablet Value PharmaPain Reliever Extra Strength Acetaminophen Aspirin Caffeine Nervine Asa 80 mg Health Mart Migraine Formula ARC FIRST AID Contains 1000 PIECES Pain Relief PM Trianal Capsules Aspirin Enteric Safety-Coated Equaline Effervescent Cold Relief Butalbital, aspirin, and caffeine Acetylsalicylic Acid Tab 325mg Asa Tablets USP 325 mg Aspirin Extra Strength With Stomach Guard Nezger Tab Ru-21 Hangover Relief Ascriptin Regular Strength Buffered Aspirin Micro-Coated Aspirin Coated Daily Low-dose Asa Alka-Seltzer Plus Severe Cold Powerfast Fizz Night Aspirin and Extended-Release Dipyridamole Direct Safety Aspirin GENUINE FIRST AID Emergency Preparedness Contains 167 Pieces Aspirin Backache Kroger Effervescent Antacid and Pain Relief Muscle Relaxant and Back Pain Relief Extra Strength Tablets 282 Tab Aspirin Regular Strength Regular Strength Dg Health Aspirin Good Sense Aspirin Uncoated Aspirin 50 Person ANSI MEDIQUE Tri Buffered Aspirin Coated Daily Low Dose Asa 81 mg Rivasa Fc Aspirin Low Dose Sugar Free Acetylsalicylic Acid, Caffeine and 8 Mg Codeine Phosphate Antidol Tablets Harris Teeter Migraine Relief Sunmark migraine relief Extra Strength Back and Body Berkley and Jensen Migraine Formula Alka Seltzer Original Migralex Dr. Mauskop Bayer Migraine Formula 4340 First Aid Kit 4313 First Aid Kit Walgreens Effervescent Cold Relief Plus Enteric Coated Asa Tablets 650mg Aspirin 81mg Quick Chews MooreBrand Aspirin Headache relief Extra Strength Aspirin Low Dose Enteric Coated Excedrin Extra Strength Geltabs Dr Pausins Low Dose Chewable Aspirin Cherry Flavor Ready America First Aid Outdoor- 107 Pieces Acetylsalicylic Acid 325mg Tab Asaphen Chewable Aspirin Pain Away Plus Circle K Headache Relief PMS-pharnal Tablets Alka Seltzer Plus 1s Blister Pack Asa 325 Mg Tablets Regular Strength Cardiospirina 81 mg Tabletas con cubierta enterica Clopidogrel Kit 4291 First Aid Kit Methoxisal-C 1/4 Buffered Aspirin ARC FIRST AID Contains 404 PIECES Bayer Headache Relief Aramark Pain-Free Extra Strength Relief Asa Extra Strength Safety Coated Low Dose Aspirin 4387 First Aid Kit Orphengesic Forte Equate Migraine Relief pain relief aspirin Low Dose Ascomp with Codeine Miniprin Regular Strength Enteric Coated Aspirin Value Pharma Aspirin Pain Reliever Excedrin Migraine Geltabs Cove Migraine Relief Alka-Seltzer Plus Multi-Symptom Cold Night Butalbital, Aspirin, Caffeine and Codeine Phosphate Enteric Coated Asprin Low Dose Extraprin Enteric coated aspirin Alka Seltzer Flavoured Exaprin-AC Oxycodone Hydrochloride and Aspirin Basic Care Aspirin Acetaminophen 250mg Aspirin 250mg Caffeine 65mg St. Joseph Safety Coated Aspirin Acetaminophen, Aspirin and Caffeine Family Wellness Effervescent Cold Relief Orange Rivasa 80 Mg EC Aspirin 81 mg Enteric Coated Excedrin Back and Body 4209 First Aid Kit PHL-asa Adventure Medical Kits 1-2 Person National Ski Patrol First Aid FIRST AID Contains 404 PIECES Aspirin Chewable Tablets Darvon N Compound Pulvule 405 Leader Extra Strength Effervescent Antacid and Pain Reliever Top Value Effervescent Cold Relief 4240 First Aid Kit Uline Aspirin Handy Solutions Headache Pain Relief CVS Health Medication and Topical Refill Pouch GenCare Headache Relief Rugby Adult Aspirin Bio-asa WinCo Foods Effervescent Cold Relief Aspirin enteric safety coated Aspirin Low Strength, Enteric Kirkland Signature Migraine Relief Asatab EC 325mg Flanax Aspirin Pain Reliever Aspirin Plus Stomach Guard Ext.stgth.caplet Methoxisal Good Sense Headache Relief Goodys Cool Orange Enteric Coated Aspirin Regular Strength Chewable Aspirin Low Dose Muscle Relaxant and Analgesic Fiorinal with Codeine Muscle Relaxant and Back Pain Relief Regular Strength Tablets BackAid Inflammatory Pain Formula Medi First Plus Pain Ache Headache, Circle K Adult Chewable Aspirin FormuCare Aspirin ARC Emergency Preparedness FIRST AID Contains 202 PIECES MICRO-COATED ASPIRIN 325 mg Asprin and Extended-release Dipyridamole Bufferin Arthritis Chewable Daily Low Dose Asa Equate Effervescent Antacid and Pain Relief Basic Dental Emergency Kit Health Sense Aspirin 81 HEB Extra Strength Effervescent Antacid and Pain Relief Rexall Aspirin Alka-Seltzer Lemon Lime Healthy Accents migraine formula Up and Up Antacid and Pain Relief 4303 First Aid Kit Alka-Seltzer Plus Multi-Symptom Cold Day and Night Chronic Pain/Fever Relief Aspirin Granules Bufferin A.S.A. Tablets 5gr BP Family Wellness Migraine Extra Strength Midol Asasantine Cap Asaphen E.C. 80 mg Aspirin 81 MG Clopidogrel/acetylsalicylic Acid Zentiva Effervescent Pain Relief Fast Relief Praxis Asa EC 81 Mg Daily Low Dose Health Mart Adult Aspirin CAREALL Aspirin North Aspirin Alka-Seltzer Plus Cold Day and Night Entrophen 325mg Tablets Rapidol Aspirin Display 2x25 Alka-Seltzer Plus Cold Sparkling Original Apo-asa Ld Excedrin Extra Strength and Excedrin Tension Headache BioElectro Extra Strength Daytime Pain Relief Extra Strength Aspirin Backache Leader Headache Formula Added Strength Up and Up Aspirin Sunmark Aspirin A.S.A. (acetylsalicylic Acid) Tab 325mg USP Aspirin NSAID Trianal Tablet Topcare Headache Relief Alka-seltzer Original Extra Strength Muscle & Back Pain Relief With Asa A.S.A. Enteric Coated Tab 650mg Alka-Seltzer Plus Cold Formula (Orange Zest) Methoxisal-C 1/8 Excedrin Migraine, TRAVEL BASIX Pain Relief Aspirin Painex Tab 0.5gr A.S.A. 325 Mg Tablet Thrulife Extra Strength Headache Relief GFA First Aid Kit Essentials - 33 Pieces Xpect Pain Away Bayer Entrophen 80mg Topcare Migraine Relief Low Dose Miniprin Enteric Safety Coated Goodys PM Pain Reliever First Aid Direct Chewable Aspirin Aspirin enteric coated low dose Natural Aspirin plus Immune Supporting Dietary Supplement St. Joseph Low Dose Aspirin Good Neighbor Pharmacy Aspirin Enteric Safety Coated St. Joseph Chewable Aspirin Natural Aspirin plus Tart Cherry Dietary Supplement Asa Extra Strength Tab 500mg Durlaza Equaline migraine formula BAYER 500 mg 4217 First Aid Kit Migraine Formula St. Joseph Chewable Low Dose Aspirin Medi First Plus Aspirin A.C.& C Tablets 4154 First Aid Kit 7 Select Adult Chewable Aspirin Aspirin Rapid Relief Dr. Juans Santo Remedio PARA LA ACIDEZ Sunmark Headache Relief Taro-dipyridamole/ Asa Alka-Seltzer Hangover Relief Moore Medical Aspirin Regular Strength Aspirin EC Walmart Pain Relief Powder Asa Extra Strength Caplet 500mg Adults Low Strength Aspirin Zee Aspirin A & C Tablets With Codeine 30mg Stanback Goodys Easy Care First Aid Kit - Comprehensive Entrophen Teva-tecnal C 1/2 Vanquish Aspirin Enteric Safety Coated Medi First Plus Tri Buffered Aspirin PhysiciansCare Extra Stregth Pain Reliever Vanquish Digital Headache Aspirin Migraine Aspirin Tablets 325mg Bubbles R Better Effervescent Cold Relief 4333 First Aid Kit Soma Best Choice Effervescent Cold Relief Chewable Aspirin Adult low dose Dr Pausins Low Dose Chewable Aspirin Orange Flavor Bayer Genuine Aspirin Extra Strength Headache, Circle K Physicians Care Aspirin Top Value Effervescent Cold Relief - Orange Bufferin Extra -strength Leader Migraine Relief Asa 975 Tab ShopRite Aspirin 4213 First Aid Kit PMS-asa MEDI-FIRST Tri Buffered Aspirin Pharbest Aspirin 325mg Sedal3x Asa Suppositories 650mg Aspirin and Dipyridamole Dollar General Effervescent Cold Relief Travel Savvy Aspirin Acetylsalicylic Acid Tab 300mg Pain Reliever Plus Sunmark aspirin adult low strength Excedrin Migraine, CVP HEALTH Good Sense Migraine Formula Jamp-asa 81mg EC Pain Reliever Entrophen Ect 975mg Extra Pain Relief Headache Pain Reliever Spasmhalt-asa-8 NobleAid PAIN RELIEVER FIRST AID Contains 1000 PIECES Aspirin Adult Low Strength DG Health migraine relief Family Wellness Migraine Relief Blowfish Splizz Pain Reliever - Orange-flavored ASPIRIN Regular Strength Coryphen 325 Tab Aspirin Night-time Aspirin Extra Strength 500mg Tab USP Aspirin Coated for Delayed Release Extra Strength Quality Choice Effervescent Antacid and Pain Relief Alka Seltzer Originial 1s Blister Pack Aramark Aspirin Phenaphen No.3 Cap Unishield Aspirin Dg Health Headache Relief Added Strength Regular Strength Enteric coated aspirin Alka-Seltzer Plus Cold Formula (Cherry Burst) Aspirin chewable low dose Alka-Seltzer Plus Day Non Drowsy Cold Medicine Citrus Bayer Aspirin Regimen enteric coated Adult Low Dose Aggrenox Equaline headache formula added strength Picot Plus Effervescent GOOD NEIGHBOR PHARMACY FIRST AID Contains 202 PIECES Aspirin Chewable Pain Stoppers Pain Relief Aspirin Low Dose Halfprin Low Dose Aspirin Meijer Effervescent Antacid and Pain Relief Effervescent Cold Relief - Orange Bayer Fast Release Chewable Adult Low Dose Aspirin Teva-oxycodan ASPIRIN Low Dose Asa Ect 650mg Smart Health Aspirin Regular Strength Regular Strength Asa Smart Sense Chewable Aspirin C2 Buffered Tab Asa and Caffeine Anacin Extra Strength Excedrin PM Triple Action Caplets GOODYS Extra Strength Headache Mixed Fruit Blast Exaprin ASPIRIN Low Strength Asa Acetylsalicylic Acid Aspirin Enteric Coated Pronal C1/4 Capsules Cardiaspirin Protect Premier Value Antacid and Pain Relief Medicine Biovanta Trip Action Green Apple and Honey Publix Super Markets Inc Smart Sense Migraine Formula Aspirin Arthritis Pain Relief 650 mg Bayer PM Effervescent Cold Relief ULINE Aspirin 292 Tab Effervescent Pain Relief Dye-Free Aspirin 81 Anacin With Codeine Tab Arco Pain Tab Aspirin EC Headache Relief Extra Strength 4142 First Aid Kit 7 Select Migraine Formula Acetylsalicylic Acid Coated Aspirin Chewable, Low Dose Aspirin Stomach Guard Regular Strength Basic Care Migraine Relief 4224 First Aid Kit Hydrocodone Bitartrate and Aspirin Pain Stoppers Extra Adult Low strength Aspirin Carisoprodol and Aspirin enteric coated aspirin Regular Strength ALKA SELTZER PLUS Cold Day and Night Effervescent BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE Carisoprodol, Aspirin and Codeine Phosphate Enteric Coated Aspirin regular strength Headache Relief PM Instantine Tab Pronal Tablets Norgesic Quality Choice Extra Strength Effervescent Antacid and Pain Relief Bayer Aspirin BC Arthritis C T Acetylsalicylic Acid Codeine and Caf Tab Coricidin D Tab Sunmark aspirin low dose Dristan Capsules Bayer Headache Adult Aspirin Regimen Low Dose Butalbital Compound Low Dose Aspirin Equate Aspirin Bayer Rapid Relief Equate Daily Low-dose Tri-buffered Asa Tab Phenaphen No.4 Cap Muscle and Back Pain Relief With Asa Enteric Coated A.S.a Jamp-asa EC Entrophen Ect 650mg Alka-Seltzer Asa Ect 325mg Biovanta Trip Action Tart Cherry and Honey Percodan Equagesic Halfprin Low Dose Top Value Effervescent Pain Relief 4196 First Aid Kit 4251 First Aid Kit Walgreens Effervescent Pain Relief Care One headache relief added strength Teva-tecnal Aspirin Tab 325mg USP Aspi-Cor Back and Body Extra Strength Ready America First Aid Pocket - 33 Pieces Aspirin, Caffeine, and Dihydrocodeine Bitartrate Migraine Relief Phenaphen No 4 Cap Methocarbamol and Aspirin Aspirin 81mg Asa EC Protection Sound Body Migraine Relief Quality Choice Effervescent Cold Relief - Orange Calmine Tab Quality Choice Pain Relief Powder Aspergum Orange 325 mg Rivasa 80mg Croquable - Tab Enteric Coated Asa Tablets 325mg Alka-Seltzer Extra Strength BAYER Aspirin Extra Strength Caplets Fiorinal-C 1/2 Goodys Migraine Relief Kirkland Signature Migraine Headache Relief Bayer Advanced Aspirin Regular Strength Orphenadrine Citrate, Aspirin and Caffeine Medique Products Aspirin Family Care Effervescent Antacid and Pain Relief Pal-pravastatin-asa Up and Up Chewable Aspirin 4365 First Aid Kit Geritrex Aspirin Green Guard Pain and Ache Relief Natural Aspirin plus Lemon and Honey Dietary Supplement Health Mart Migraine Relief Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored Aspirin 81 mg Ac and C Tab 1/8gr Bufferin Regular Strength Pain Relief Pain Reliever Added Strength Acetaminophen Aspirin and Caffeine Equaline aspirin adult low dose Aspirin Adult Low Strength Aspirin Low Strength Chewable Aspirin Rexall Coated Daily Low Dose Asa TopCare Aspirin Aspirin 325 mg 4244 First Aid Kit Aspirin Express Pack Aspirin Adult low dose Uricalm Intensive Aspirin Coated Caplets 325 mg Extra Strength Headache Relief EC-81Aspirin Enteric Coated Headache Formula Added Strength Pain Relief Maximum Strength Medpurine Reese Headache Powders Bayer Plus Extra Strength MYGRIN Nighttime Assured Aspirin Ache and Pain Relief to Go Goodys Cool Orange Headache Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Up and Up Migraine Relief Asprin 4342 First Aid Kit Aspirin Safety Coated Enteric, Regular Strength Asa 500 Mg Tablets Extra Strength Anacin Caplets Medi-First Aspirin Berkley and Jensen Migraine Relief Acetylsalicylic Acid 325mg Tablets USP Adult Low Strength Aspirin 365 Everyday Value Aspirin Anacin ES Aspirin Plus Stomach Guard Tab Bc Max Aspirin Enteric Coated, Regular Strength Medique Medi Seltzer Pain Relief Aspirin Chewable, Low Dose Physicians Care Extra Strength Pain Reliever Exact Coated Daily Low-dose Asa Green Guard Tri Buffered Aspirin relief Pronal - C1/2 Capsules Aspirin Low Dose Safety Coated Asa Ect 600mg Good Sense Effervescent Cold Relief Aspirin to Go Good Sense headache formula added strength Signature Care Effervescent Antacid and Pain Relief Care One migraine relief Coricidin Tab Good Sense Aspirin Enteric Safety Coated A.S.A. Rugby Aspirin Pravigard Pac Regular Strength Pain Relief Coryphen 650 Codeine 30 Tab Alka-Seltzer Plus Cold and Cough Formula Asa, Caffeine & 8mg Codeine Phosphate Aspirin Chewable Tablets - 325mg 4229 First Aid Kit Alka Seltzer Plus Cold London Drugs Coated Daily Low-dose Asa Novasen Aspirin 325mg Extra Strength Pain Relief Right Remedies Aspirin Low Dose 81 mg Alka-Seltzer XTRA STRENGTH GOODYS Hangover ShopRite Migraine Formula Chewable Low Dose Asa Tab 325mg Ana-dent Excedrin PM Triple Action Caplets and Excedrin Tension Headache Aspirin Enteric Coated Caplet 325mg Publix Fast Relief Effervescent BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES Aspirin and Omeprazole Delayed-release Tab Pain Terminator 2 Severe Extra Strength Headache Low dose Chewable Aspirin Alka-Seltzer Plus Severe Cold PowerFast Fizz Orange Zest Lil Drug Store Headache Relief Extra Strength 217 Apo Asa Tab 325mg Asa 80 Aspirin and Dipyridamole Extended Release Pain Relief Extra Strength Low Dose Chewable Aspirin 4232 First Aid Kit Aspirin Pain reliver Norgesic Forte Bayer Low Dose Formu Care pain reliever added strength Quality Choice Effervescent Cold Relief Plus Alka-Seltzer Plus Severe Cold PowerFast Fizz Drug Mart Effervescent Pain Relief Low Dose Aspirin Low Dose Circle K Headache Relief Extra Strength Entrophen Ect 500mg Genuine First Aid Industrial First Aid 692 Tab McKesson Aspirin Tylo Migraine (Acetaminophen) Adult Low Dose Enteric Coated Aspirin Rapidol Aspirin Robaxisal Extra Strength Basic Care Headache Relief Duoplavin Freds Effervescent Antacid Pain Relief Best Choice Pain Relief Powder Leader Low Dose Aspirin Pharbest Regular Strength Aspirin TopCare Effervescent Antacid and Pain Relief Asa-325 Comprimes Retard Butalbital, Aspirin, and Caffeine Pain Stoppers EX Headache Relief to Go Aspirin - Children's Size - Tablets 4225 First Aid Kit Rapid Comfort Aspirin ARC FIRST AID Contains 101 PIECES Aspirin 50 CT Walgreens Antacid Pain Relief Extra Strength Crane Safety Aspirin 217 Strong Tab Advanced Pain Reliever Chewable Low Dose Aspirin Pain Aid ESF Only For FIRST AID MEDICINE Smart Sense Effervescent Cold Relief Neo Tigol Tab Health Mart Regular Strength Enteric Coated Aspirin Good Neighbor Pharmacy aspirin orange flavor chewable Yosprala Dolodol Headache Formula Extra Strength Fiorinal Sunmark Adult Aspirin Coryphen 650 Tab Sunmark Migraine Relief Tabcin 500 4211 First Aid Kit Aspergum 325 Mg (cherry) Trianal C½ Pain Free Plus Aspirin Pain Relief Smart Sense migraine relief Herbopyrine Tab 325mg FIRST AID Contains 101 PIECES HARDCASE Teva-tecnal C 1/4 Vazalore Excedrin Extra Strength Coachs First Aid Contains 102 Pieces
Indication	Pain, fever, and inflammation Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label]. The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label]. Other indications ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include: Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label]. Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label]. For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label]. For the prevention of thromboembolism after hip replacement surgery [FDA label]. For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label]. Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label]. Important note regarding use of the extended-release formulation [F4405] In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
Categories	Acids, Carbocyclic Agents causing angioedema Agents causing hyperkalemia Agents that produce hypertension Alimentary Tract and Metabolism Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antiinflammatory and Antirheumatic Products Antiplatelet agents Antipyretics Benzene Derivatives Blood and Blood Forming Organs Cardiovascular Agents Cyclooxygenase Inhibitors Cytochrome P-450 CYP2C19 Inducers Cytochrome P-450 CYP2C19 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Decreased Platelet Aggregation Decreased Prostaglandin Production Drugs that are Mainly Renally Excreted Hematologic Agents Hydroxybenzoates Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS OAT1/SLC22A6 inhibitors OAT3/SLC22A8 Inhibitors P-glycoprotein inducers P-glycoprotein substrates Peripheral Nervous System Agents Platelet Aggregation Inhibitors Excl. Heparin Salicylates Salicylic Acid and Derivatives Sensory System Agents Stomatological Preparations UGT1A6 substrate
ATC-Code	B01AC06 C07FX04 C10BX04 M01BA03 C10BX02 N02BA71 B01AC56 N02AJ07 N02AJ02 N02BA01 B01AF51 C10BX05 N02BA51 A01AD05 C10BX01 C07FX03 N02AJ18 C10BX12 C10BX08 C10BX06 C07FX02
CAS number	50-78-2

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown	inhibitor
3-hydroxy-3-methylglutaryl-coenzyme A reductase	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYEC...	unknown	inhibitor
Prostaglandin G/H synthase 2	MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFY...	unknown	inhibitor
Aldo-keto reductase family 1 member C1	MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHID...	unknown	inhibitor
5'-AMP-activated protein kinase	MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTG...	unknown	activator
Endothelin-1 receptor	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVT...	unknown	inhibitor
Cellular tumor antigen p53	MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDI...	unknown	inducer
Endoplasmic reticulum chaperone BiP	MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRV...	unknown	inhibitor,binder
Ribosomal protein S6 kinase alpha-3	MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEI...	unknown	inhibitor
NF-kappa-B inhibitor alpha	MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQ...	unknown	inhibitor
Tumor necrosis factor-inducible gene 6 protein	MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLT...	unknown	inhibitor,downregulator
Caspase-1	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATV...	unknown	inhibitor,downregulator
Caspase-3	MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIII...	unknown	inhibitor,downregulator
Inhibitor of nuclear factor kappa-B kinase subunit beta	MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQEL...	unknown
Extracellular signal-regulated kinase (ERK)	MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR...	unknown
G1/S-specific cyclin-D1	MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQK...	unknown	downregulator
Myc proto-oncogene protein	MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQ...	unknown	downregulator
Proliferating cell nuclear antigen	MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQL...	unknown	downregulator
Cyclin A	-	unknown	downregulator
Sialidase-1	MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAEND...	unknown	inhibitor
Cytochrome P450 2C19	MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDV...	unknown	inducer
Cytochrome P450 2C9	MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...	unknown	substrate
UDP-glucuronosyltransferase 1-6	MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLS...	unknown	substrate
Arylamine N-acetyltransferase 2	MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMEL...	unknown	substrate
Solute carrier family 22 member 6	MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCR...	unknown	inhibitor
ATP-dependent translocase ABCB1	MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLY...	unknown	substrate,inducer,modulator
Organic anion transporter 3	MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCR...	unknown	inhibitor
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL25
PubChem	2244
ChEMBL	CHEMBL25
ChEBI	CHEBI:15365
CCDC/CSD	ACSALA21, ACSALA23, ACSALA14, TAZRAO01, DIFQAK, ACSALA20, DIPJAQ, VUGMIT, ACSALA26, ACSALA15, ARIFOX, KEWNOQ, ACSALA17, ACSALA25, ACSALA01, ACSALA19, SIBYUA, ACSALA27, TAZRAO, HUNJEH, ACSALA28, SIBYUA01, ACSALA02, ACSALA08, ACSALA07, ACSALA05, ACSALA03, ACSALA04, ACSALA06, ACSALA11, ACSALA09, SIBYUA02, ACSALA29, GARYEH, HAPCOU
COD	7126911, 1515582, 1515581, 2104857, 1516479, 1516481, 1516480, 4100978, 7247818, 7247819, 7050897, 7050898, 7050899, 7050900, 7050901, 7050902, 7050903