Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.
Synonyms
2-methoxyl-4-vinylphenol
o-Methoxyphenol
1-hydroxy-2-methoxybenzene
Guaiacol carbonate
o-guaiacol
Guaiacol hydrochloride
Guaiacol
o-hydroxyanisole
Pyrocatechol monomethyl ether
2-methoxyphenol
Pyroguaiac acid
Brand Names
Gouttes Dentaires
Dry Socket
Jamp-cough Suppositories Adult
Pastilles Valda
Valda Pastilles Lemon Flavoured
Creo-rectal Enfants/children
Demo-cineol Adultes/adults
Dentalgar Liq
Valda Pastilles
Creo-rectal Adultes/adults
Creo-rectal Nourrisson
Demo-cineol Enfants/children
Demo Cineol Inj
Jamp-suppositories Children
Analgesic Balm
Indication
It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
