Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.
Synonyms
o-guaiacol
Pyroguaiac acid
o-hydroxyanisole
Pyrocatechol monomethyl ether
Guaiacol
Guaiacol carbonate
Guaiacol hydrochloride
1-hydroxy-2-methoxybenzene
2-methoxyphenol
2-methoxyl-4-vinylphenol
o-Methoxyphenol
Brand Names
Analgesic Balm
Creo-rectal Enfants/children
Valda Pastilles
Creo-rectal Nourrisson
Valda Pastilles Lemon Flavoured
Demo Cineol Inj
Pastilles Valda
Dry Socket
Jamp-suppositories Children
Gouttes Dentaires
Jamp-cough Suppositories Adult
Demo-cineol Enfants/children
Dentalgar Liq
Creo-rectal Adultes/adults
Demo-cineol Adultes/adults
Indication
It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
