DrugBank ID DB00281 Name Lidocaine Groups Description Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances that may benefit from its action, including the treatment of premature ejaculation [A177625]. Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. It is even included in the World Health Organization's List of Essential Medicines [L6055]. Synonyms Lidocaine hydrochloride 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide α-diethylamino-2,6-dimethylacetanilide Lidocaina Lidocainum
alpha-diethylamino-2,6-dimethylacetanilide Lidocaine hydrochloride anhydrous Lidocaine Lidocaína 2-(Diethylamino)-2',6'-acetoxylidide Lignocaine more Brand Names Precaine Lidothol Patch Ozonol Antibiotic Plus Ont Soothee Patch Ana-Lex
Lidocaine Hydrochloride, Hydrocortisone Acetate Small Cuts and Burns 4379 First Aid Kit Lidodan Ointment 5% Lidocaine Ont 5% Graham Flavored BLT Skin Cream Physician Force Maximum Strength Pain Relief Point Of Care LM DEP 2 Pro Comfort 8 Hours Patch JOINT AND MUSCLE RELIEF 750 mg Xylocaine Mpf 1.5% With Epinephrine Jamshidi Bone Marrow Biopsy Tray Restoriden Lidocaine Cream Lidotin Lidocaine and Tetracaine Spinal Anesthesia Tray Numbing Label Lidosol Xylocaine -MPF First Aid Antiseptic Rite Aid pharmacy Icy Hot with Lidocaine No-Mess Hot Cold Lidocaine With Menthol Dyve Comfort L Beta Inject Kit Bio-Scriptives Lidum 4108 First Aid Kit 4332 First Aid Kit 4117 First Aid Kit INKED SCIENCE LIDOCAINE 4 Percent 4045 First Aid Kit 4090 First Aid Kit 4155 First Aid Kit 7-Select After Sun Lidicaine HCl Pain-Relieving with Aloe Vera 4276 First Aid Kit Lumbar Puncture Tray 1% Sting Relief Pad Lidocaine HCl 4 Percent and Menthol 4 Percent OKeeffes Healthy Feet Dexlido M-C Basic Biopsy Tray 1% Burn Relief Gel With Lidocaine Arrow Pneumothorax Kit CVSLidocaineAntisepticSpray Point Relief LidoSpot Itch Relief Max Strength Ultimate Lidocaine Pain Relief Patch 4102 First Aid Kit ReadySharp Anesthetics plus MethylPrednisolone 80 LidoPatch Pain Relief Lido AID Lmx5 Lidoxryl 4231First Aid Kit Keepan A Solmate Burn Relief Gel 4068 First Aid Kit Leader PAIN RELIEF PATCHES biochemistry PAIN RELIEF FOOT ACTIVE CBD Medic - Odor-Free Serious Relief Mlp A-1 Physician EZ Use Joint Tunnel and Trigger Kit II Kroger Pain Relief Lidocaine Patch Neosporin Plus Lidocaine Solmara Aerowound Blood Clotting First Aid ProStat Blood Clotting First Aid Salonpas LIDOCAINE Pain Relieving PRILOVIX Ultralite Plus Pacing Catheter Introducer Kit Acp-001px Lixtraxen 1% 4066 First Aid Kit Venia Patch Premium Pain Patch Extra Strength Liquid Hemorrhoid Relief Gel 4362 First Aid Kit Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Lidotral Five Percent with Menthol Pre-wax Spray Reg Truu Balance Pain Relief Instant Burn Relief Aloe Extra CVS Derma Gel Relief Paraid Burn Equate Pain Relieving Cream Lidocaine 4389 First Aid Kit Odynia-U JOINT AND MUSCLE RELIEF 450 mg Your Label Here Blood Clotting First Aid Diclovix XYLOCAINE- MPF (LIDOCAINE HCl ) Nox-A-Sting Dyural LM Kit Botanika Life Ultra-Relief Pain Rub Premjact Intimale Lidocaine Delay Ozonol Antibiotics Plus Alivio Lidodan Cream 4% LidoPlus Pain Relief Redicare Burn Gel 4199 First Aid Kit ReadySharp Anesthetics plus Ketorolac Centipaine for Pain Control SKINS DELAY Maximum Strength Lidocaine Xylocaine RR Roll-On for Pain FirstCare Pain Relief Gel Patch FIRST AID Contains 101 PIECES HARDCASE Lido-K Pharmassist Soothenel Gel Bite and Sting Relief Wipe Releevia LM Patch Lidomyxin LidAll CANNA NUMB Roll On Zylotrol Plus Menthocin Patch with Lidocaine - Strong Silvera Pain Relief Patch Dbk Microcaine Topical Analgesic Lido Pain Relief Pain Relieving Cleansing Spray 4078 First Aid Kit JUANCHI Tattoo Numbing LidoER First Aid and Burn Numb Soothe Activate Joint and Muscle Relief 4107 First Aid Kit Walgreen Pain Relieving Fragrance Free DermacinRx Prizopak Hot and Cold Lidocaine with Menthol Patch Pain Relief Wegmans Aloe After Sun Gel with Lidocaine HCl External Analgesic DYNAMO DELAY Black Label TheraCare 4% Lidocaine Cream Synvexia 4225 First Aid Kit Assured Pain Relief Walgreens First Aid Antiseptic Medi-patch With Lidocaine Rx Pomoda Dragon Pain Numbing Zilactin-L Lidocaine Pain Relief Patch 4139 First Aid Kit Harmony Hemp NeuroComfort Pain Relief Lotion500 LidoSport Pain Relief Maxocaine Pain Relieving Roll-ON ReCellTis Wound Cream Lidocaine HCl Topical Solution AvaDerm Central Venous Catetherization Kit CVS Health Cold and Hot Roll-On Arthrocare Maximum Arthritis Pain Relief GREEN GUARD Topical Pain Relief Antiseptic Formula Filled Swab 1st Medxpatch With Lidocaine 4%-rx Lidocaine 23% / Tetracaine 7% Relador Pak with Occlusive Dressing Anorectal Smartshield After Sun Numbify Smooth LidoCream 10 Walgreens Sunburn Relief BlueStop Max Betacaine Gel Flanax Back Pain Relief Extra Strength Naturally Hl Itch Relief Nanonumb Burn relief aloe Daylogic Venipuncture CPI Lidocaine Hydrochloride and Dextrose Comfort EZ Pain Relief Patch Instillagel Laryng O Jet Kit CVS Health Antibiotic Free Wound and Pain Relief Aflexeryl-LC 4101 First Aid Kit Anesthetic HUSH Fast Acting Topical Anesthetic SunBurnt PLUS Pain Relief Kroger Aloe Vera Pain Relieving Pro Numb 4305 First Aid Kit Aramark Burn Gel 4103 First Aid Kit Medi-Quik First Aid Antiseptic Lidocaine and Prilocaine Maxilene 4 Equate Pain Relief Cream BurnX Pain Relieving Burn Icy Hot Lidocaine Dry Lidocaine Hydrochloride Injection USP 2% 4251 First Aid Kit GelAzul Roll-On DermacinRx Lexifen Transderm-IQ PMS-lidocaine Viscous 2% General Numb Hydrocath Central Venous Catheter Kit Super Magic Man Premium Gold Your Logo Here Antiseptic First Aid Pain Relieving Cleansing Xylocaine Topical 4% 4076 First Aid Kit Gigi Anesthetic Numbing 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Gel Professional Tatoo Care Medi-patch With Lidocaine Budpak First Aid Xylocaine 1% 0.4% Lidocaine Hydrochloride and 5% Dextrose Injection Xylocaine Mpf 4249 First Aid Kit Family Wellness Anorectal Lidocaine LifeStyles EPIC Male Genital Desensitizer Base Laboratories Lidocaine Anesthetic Pain Relief Lido-Prilo Caine Pack Welly Superhero Supplies Kit Genuine First Aid First Aid Antiseptic Pain Relieving Cream Wound Debridement Kit Antibiotic Cream Plus Pain Relief Cml Zovacil 5 4162 First Aid Kit Lidocaine creme CVS Health Maximum Strength Lidocaine Pain Relief Cream Plus Menthol Performance Brands Steel Releaf Pain Relieving Liquid Meijer Maximum strength pain relieving cleansing 4207 First Aid Kit 4154 First Aid Kit Preattached Lta Kit TLC Plus Anesthetic S Amour CBD TheraCare Maximum Strength Pain Relief Patch Harmony NeuroComfort 4% Lidocaine Pain Relief Cream-Gel 1000mg Point Relief LidoSpot with Menthol 4373 First Aid Kit 4395 First Aid Kit 4402 First Aid Kit ReCellTis Serum X Xylocaine Spray Zilacaine Patch Electrum Numb Foam Reciphexamine Scar Zone Burn Extra Strength Burn Relief Topical Analgesic and Antiseptic Rite Aid Hot and Cold Pain Relief Pain Relieving Lidocaine 0.2% In 5% Dextrose Inj Neptune Ice Patch Noble Art Numbing Cream with Lidocaine LidoFLEX Elbow, Single Pouch 4248 First Aid Kit Lmc Pain Relief Rite Aid Pain Itch Relief Pain Relief Max Strength Western Family Aloe Vera Moisturizing Inderma MD Antiseptic 4157 First Aid Kit Aloe Lidodan Endotracheal Non-aerosol Spray Eha Numb Gel Anesthetic Bed Bug Instant Bite Relief GENUINE FIRST AID Emergency Preparedness Contains 167 Pieces Kit Breakroom Office First Aid Medi-First Plus Burn Cream Pain Relieving MEDI-FIRST Topical Analgesic Base Laboratories Numb Gel Numb 100 Lido GB-300 Neptune Ice ACME FIRST AID Contains 404 PIECES Soothing Gel With Lidocaine Lidocaine Maximum Strength Xylocaine 2% With Epinephrine 1:200000 Atendia NATURES CRAFT LIDOCAINE Male Genital Desensitizer Burn Ease, 3.5g 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Lidospot 4191 First Aid Kit Signature Care Lidocaine Cream Lidotral 3.88% Roll on TriXylitral First Aid Spray 4106 First Aid Kit Wound and Burn Care Refill Pack CVS Health XL Lidocaine Pain Relief Walgreens PAIN RELIEVING Lidocaine Pain Relief with Lavender EPIC Burn Cream Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride Lidoderm 5 Workvie Roll On Lidocaine Menthol Pain Relief Hyronan Zeyocaine SkyaDerm-LP 4370 First Aid Kit 4391 First Aid Kit 4396 First Aid Kit Mentholix 4309 First Aid Kit Vpmax Premjact Male Desensitizer Pound International Burn Relief Max Strength Professional Medicated DNA Collection 4153 First Aid Kit LevigoSP Akten Xesso Strawberry Rear Comfort Glide 4% Lidocaine 4302 First Aid Kit Acunistat-30 Promescent Lidocort Cbd4 Freeze Pump Vanishing Scent Warrior Rectal Care Medicated Buccal DNA Collection Kit Re-Lieved 4% Lidocaine Fabric Tape Terrasil Cold Sore Treatment Max Lipocaine 5 Burnrelief Bruselix Gel Kendra SKIN PROTECTION and PAIN RELIEF FOR 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STRENGTH JOINT AND MUSCLE RELIEF 1500 mg ReadySharp Lidocaine Doctor Butler Hemorrhoid and Fissure Advanced Formula Priloheal Plus 30 Lidenzal 2% Lidocaine Hydrochloride 0.5% and Epinephrine 1:200000 Injection USP Max 4 Men - Max Control Male Sex Prolong Unscented Paracentesis Tray W Boasberg Catheter Set Xylocaine 2% Epidural Extra Strength Sunburn Relief Phenyl-Lido ECOLAB Blood Clotting Walgreens Pain Relieving with Lavender Analgesic Realheal-I Transderm Iq Lidozion 4243 First Aid Kit Xylocaine Dental Lidocaine HCl 2% and Epinephrine 1:100,000 4258 First Aid Kit 4086 First Aid Kit Xylocaine Dental Lidocaine Hydrochloride 2% and Epinephrine 1:50,000 Trubrexa Meijer Lidocaine Pain Relief Patch Assortment Medium Medi-quik First Aid Spray Green Guard Derma-Caine Burn KY Duration for Him Gold Bond Medicated Pain and Itch Relief NuLido Curist Lidocaine Patch Maximum Strength Continuous Epidural Anesthesia Tray Maximum Strength Burn Relief Aloe Gel Scherer Labs Puroxcin Leva Set with 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Lidocaine Diclona Gel Meijer Burn Relief Absorbine Jr Pro No Mess Roll-on Plus Medicated Buccal DNA Collection Kit 2 DermaRad Relief Post Radiation Calming Odynia-UUltra Patch Ultra Patch Top Safety First Aid Burn Cream First Aid Antiseptic Well at Walgreens Numbing Cream DCH Rapid Relief Hemorrhoidal Veltrix First Aid Burn Relief Rite Aid Lidolog Kit TheraCare Pain Relieving Patch with Lidocaine Hempvana Maximum Strength Pain Relief Cream Xesso Rear Comfort Glide Satohap Lidocaine Hydrochloride 4 Percent Pain Relieving 4206 First Aid Kit Lyracaine Gel Pain Relief Roll-on Good Sense Alcoholada Gel Pain Relieving Pain 4319 First Aid Kit Nuvakaan II Lidotral 3.88 Percent Plus Hydrocortisone 1 Percent 4185 First Aid Kit 4187 First Aid Kit LenzaPro Flex Harmony Hemp NeuroComfort Pain Relief Gel 500 Health Mart Lidocaine The Solution Gabapal Hustle Helper Comfort Enhancing Anesthetic Antimicrobial Wash Hempvana Maximum Strength Pain Relief Topical Anesthetic LIDOCAINE HCl AND EPINEPHRINE Topcare Pain Relief Patches FranklyNumb 2 MAXOCAINE Topical Anesthetic Anorectal 4051 First Aid Kit 25 Person ANSI 4205 First Aid Kit Alocane Emergency Burn 4274 First Aid Kit Aspercreme with Lidocaine Foot Pain Creme Bikini Zone Medicated ARC FIRST AID Contains 404 PIECES Safetec Burn Spray 4283 First Aid Kit Swiss Navy EnduranceRx Gen7T Plus Cadira Compliant Blood Stat Footworks Maximum Strength Cracked Heel Anecream 5 Meijer Analgesic Lidocaine Topical Analgesic Lidosite Naturally HL Extra Strength Hemorrhoid Numbing Walgreens Hemorrhoidal Pain Relief POWERECT Lidocaine Male Delay Numpot Topical Anesthetic Lidocare Arm, Neck, Leg Derma Numb Pain Relief MAXOCAINE Lidocaine Hemp Oil Topical Analgesic Aprizio Pak II Relador Pak Plus P-Care K80MX Lumbar Puncture Tray 1% Pediatric/infant THERA CARE 24hrs Lidocaine Patch Xylocaine 1.5% W Epinephrine 1:200000 Test Dose Extra Strength Pruritis Relief MLK F3 Kit Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% 4334 First Aid Kit CVS Lidocaine Pain Relief Dry 4074 First Aid Kit Insta Relief DM 4288 First Aid Kit Rite Aid Lidocaine Roll on Lidocaine Patch Pro-C-Dure 4 Kit Ever Ready First Aid Foot Works Cracked Heel X3 On The Go First Aid Burn Relief Spray eLenza Patch 1st Medxpatch With Lidocaine 4% FIRST BXN Mouthwash ReadySharp Anesthetics plus Betamethasone ReadySharp-K Hunter Beach 4% COOL CURE Pain Relief PainGo KFT Caring Mills Relief Patch with Lidocaine First Aid Only Burn MLK F4 Kit 4224 First Aid Kit Select Brand Burn Relief Dr. Numb Lidocaine Pain Relief Gel Patch Vonaflex Arthrogram Tray 1% ReadySharp-P80 Microvix L Solarcaine First Aid Lidocaine Spray Blockaid Xylocaine 0.5% W Epinephrine 1:200000 Medi-derm / L With Lidocaine 4253 First Aid Kit JOIYA Ease Warrior Burn Relief Aloe Maximum Strength Dr Butlers Hemorrhoid and Fissure PF Trifena Formula 2 Skin Care 4131 First Aid Kit Lidocaine HCl - Hydrocortisone Acetate Meijer Pain Relief Patches Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%. 4311 First Aid Kit Tidl Pain Relief Massaging Roll-ON Lidonexe DCH Burn Relief First Aid Kit Medication Filled Swabs Ear Pain MD Lidocaine 4 Percent and Menthol 1 Percent Roll-On MG217CoolingBurnSpray Numbs Up Zensa Anorectal Gel Res-Q Analgesic Topical Pain Relief Dragon Pain Numbing Roll-On Renovo Lido5 Zone 1 Ritual Tattoo Xylocard One Gm Additive Unit 20% Inj Lidotral 5% Gel Kit Large Office First Aid Odynia-R Regular CBD Pain Lidocaine Hydrochloride - Hydrocortisone Acetate Extra Strength Skin Repair Pain Relief Roll-on Pure-Aid Xylocaine 2% W Epinephrine 1:100000 4301 First Aid Kit Hempvana Knee Bird Ultra Strength Pain Relief Greencaine Blast QC Lidocaine Maximum Strength 4310 First Aid Kit Cool N Heat Lidocaine Dry Triple Antibiotic Siterol Chi-Myst Resolve Topical Tidl Pain Relief Numbing Tidl Omeza Licodaine Pain and Itch Relief Oil Xylocaine Co2 Inj Lidocaine Hydrochloride Viscous Tpr20 Analgesic AgonEaze Astero CBD4 pain relief cream Lidocan V Lid O Creme Roll On Hemorrhoid Relief Cold Sore TREATMENT Curist Lidocaine Numbing Relief DCH Pain Relief AUVON LIDOCAINE MENTHOL Pain Relief 4210 First Aid Kit Icy Hot with Lidocaine Zyvodol Extra Strength Shingle Chickenpox Relief Precision Pain Relief Audacious Wreck Relief Lidocaine Hydrochloride Hydrocortisone Acetate Mentholatum Lidocaine Heat Lidocaine HCl 0.8% and 5% Dextrose Inj 4336 First Aid Kit Mlk F4-C Aloe Vera Gel Pain and Itch Relief 4% Lidocaine Lidenzal 1% Superior Pain and Itch Relief Renuu Patch more Indication Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930]. Categories Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Agents that reduce seizure threshold Amides Amines Analgesics and Anesthetics
Anesthetics Anesthetics for Topical Use Anesthetics, Local Anilides Aniline Compounds Antiarrhythmic agents Antiarrhythmics, Class I Antiarrhythmics, Class Ib Antipruritics and Local Anesthetics Antipruritics, Incl. Antihistamines, Anesthetics, Etc. Cardiac Therapy Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (moderate) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2A6 Substrates Cytochrome P-450 CYP2B6 Substrates Cytochrome P-450 CYP2C18 Substrates Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 CYP3A7 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Local Anesthesia Local Anesthetics (Amide) Membrane Transport Modulators Methemoglobinemia Associated Agents Nervous System Neuraxial Anesthetics Ophthalmologicals Otologicals P-glycoprotein inhibitors Peripheral Nervous System Agents Sensory System Agents Sodium Channel Blockers Throat Preparations Vasoprotectives Voltage-Gated Sodium Channel Blockers more ATC-Code S01HA07 D04AB01 R02AD02 C01BB01 S02DA01
N01BB52 C05AD01 N01BB02 more CAS number 137-58-6 
