DrugBank ID DB00281 Name Lidocaine Groups Description Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances that may benefit from its action, including the treatment of premature ejaculation [A177625]. Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. It is even included in the World Health Organization's List of Essential Medicines [L6055]. Synonyms α-diethylamino-2,6-dimethylacetanilide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide Lidocaine 2-(Diethylamino)-2',6'-acetoxylidide Lignocaine
Lidocaine hydrochloride anhydrous alpha-diethylamino-2,6-dimethylacetanilide Lidocaina Lidocaine hydrochloride Lidocaína Lidocainum more Brand Names CBD4 pain relief cream Lidotral Five Percent Renovo Lido5 4022 First Aid Kit Tatoo Care
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Advanced Seal Barrier plus Pain Relief Jamshidi Bone Marrow Biopsy Tray Burn Relief Aloe 4248 First Aid Kit Extra Strength Scar Prevention PS-3866 Burn Ease, 0.9g Lidodan 4% Topical Solution Proplex Lidocaine Nothing Precise Cooling Pain Relief Cream H-Paxin AsperFlex Naturally HL Extra Strength Hand Care RECOVERY Numbing Pain Relieving Cleansing GFA First Aid 36 Unit Metal Case Kope Pain relief gel Aspercreme with Lidocaine Essential Oils Rosemary Mint Hydrocaine Trubrexa Pain Relieving Lidocaine Numbing Cream 4049 First Aid Kit Zylotrol Maximum Pain Lidocore Xylocaine Jelly 2% Polysporin Burn Formula Cream Tylenol Precise Pain Relieving Trifena Numquick Analgesic Tattoo Numbing Cream Ebsl-5 DAYMARK FAK-35 First Aid Meijer Pain Relieving Max Strength with Lavender Essential Oil Analgesic MAXIMUM STRENGTH HEMORRHOIDAL RELIEF with Finger Cots Plum Smooth Plumb Numb Gelee 4088 First Aid Kit First Aid GNP LidoRxKit 4148 First Aid Kit 4239 First Aid Kit Comfort EZ Extra Strength Pain Relief Patch Lidocaine 4% Topical Anesthetic Cream 4189 First Aid Kit Medi-quik First Aid Spray Pharmassist Soothenel Gel ReadySharp-P80 DX2 OraGenomic Medicated DNA Collection Screen ReadySharp Lidocaine Otizol HC Liq Lansinoh Pain Relieving Lidocaine 4% Lidocaine HCl Inj 1% 4234 First Aid Kit DermacinRx Lexifen ProloGel Urgent Care Bite and Sting Relief Wipe Roll-On Pain Lidocaine Hydrochloride Injection, USP 1% 4237 First Aid Kit RadX LexiLido First Aid Burn Relief Rite Aid Emla Base Numb Topical Anesthetic Natureplex Lidocaine 4% Odynia-U Lipovite Mcl Aloe Vera Gel General Numb Tetrakam Aspercreme with Lidocaine Numb Nuts Hustle Helper Cathejell 4114 First Aid Kit Numbskin Walgreens Hemorrhoidal Pain Relief Ori-power DermacinRx ZRM Pak Signature Care Lidocaine Cream Lidocaine Pain Relief Patch Avalin-RX Eha Numbify Sanitize Kit Large Office First Aid Absorbine jr. 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anesthetics L The Solution Cacitrix Medi-First Plus Burn Cream Meijer Pain Relief Patches ACAT SUK Kit (Accelerated COVID-19 Antibody Test Single Use Kit) CANNA NUMB Roll On H-Releve Hemorrhoidal Curist Lidocaine Patch Maximum Strength 4047 Fist Aid Kit Octocaine 50 Lidocanna Lidodan Jelly 2%(single Use Syringe) Scar Zone Burn Topical Analgesic and Antiseptic 50 Person ANSI Dragon Pain Relief DCH Nerve Pain Relief Roll-On 4163 First Aid Kit Aerowound Blood Clotting First Aid BL-Contrast Livixil Pak Gigi Anesthetic Numbing Coralite Lidocaine Pain Relief Anorectal Equate 4359 First Aid Kit SWISS NAVY Endurance Rx 4089 First Aid Kit Dyural 40 Kit Burn Relief Gel Pain Relief Roll On Evora Labs DermacinRx Cinlone-I CPI Pliaglis RadiaGuard Advanced Radiation Relief 4186 First Aid Kit Youcopia Tattoo Numbing Premium Lidocaine 5% Extra 0.4% Lidocaine Hydrochloride and 5% Dextrose Injection USP LidoSport Pain Relief Easy Care First Aid - All Purpose LIDOCAINE HCl AND EPINEPHRINE PRILOVIX Lite 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First Aid Kit 64058024 Lidosporin Cream Safetec Sting Relief Scar Patch Xylocaine 5% Spinal Ocean Breeze Pain Relief 4257 First Aid Kit NeuroMed 7 Topical Pain Relief 4119 First Aid Kit JTT Physicians Joint, Tunnel and Trigger Arthrocare Maximum Arthritis Pain Relief LidoStat MediRelief Cml Hot and Cold with Lidocaine Pain Relieving TopCare Pain Relief Patch Gabacaine 4255 First Aid Kit Cbd-kings With Lidocaine 4% Freds Antiseptic Wash Lido Pain Relief Maximum Strength Burn Relief Aloe Gel Scherer Labs Herpecin Pain Relief 4258 First Aid Kit 4134 First Aid Kit ARC FIRST AID Contains 404 PIECES Betalido-C Aprizio Pak II Prikaan Lite AnodyneRx Icy Hot Lidocaine No Mess Applicator Plus Menthol 4392 First Aid Kit Band-aid Brand Antiseptic Wash Prizopak II Scalpanumb Pro-C-Dure 1 Kit Redicare Blood Clotting Dermalid AUVON LIDOCAINE MENTHOL Pain Relief HealthWise Lidocaine Pain relief Extra Strength Postherpetic Neuralgia Relief Antibiotic Plus Pain Relief Cream Extra Strength Naturally Hl 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Curacaine Lidocaine 2% and Epinephrine 1:100 000 Numb Soothe Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) Phenyl-Lido Burn Treatment Physician EZ Use Joint Tunnel and Trigger Kit II Lidocaine Hydrochloride Solution 4155 First Aid Kit AvaDerm Foot Hangover Bed Bug Instant Bite Relief 4281 First Aid Kit Hot and Cold Cream with Lidocaine Pain Relieving Seaford Nifedipine and Lidocaine Hydrochloride Cream 4222 First Aid Kit Icy Hot Lidocaine Dry Uber Numb Topical Anesthetic First Aid Research Bacitraycin Plus Maximum Vertical Xylocaine 2% Epidural 4275 First Aid Kit Prikaan Lidocaine Pain Relieving Creme Lidocaine Hci and Dextrose PainPatrol CBD Pain Relief with Lidocaine MLK F4 Kit DermaNumb Analgesic Fast Freeze Lidocaine Pro Comfort 8 Hours Patch Walg Aftrsn Burn Relief 4279 First Aid Kit Aspercreme with Lidocaine No-Mess Applicator Dentsply 2% Lidocaine With Epinephrine 1:50,000 Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% Zingo Topicaine Pain Relief Roll-on Leader After Sun Cooling Zovacil 5 Dermatologic Relief 4284 First Aid Kit First Aid Kit Medication Filled Swabs Lidocaine Hci and Epinephrine With Epinephrine LidoPatch Neolinn Lidocan VI 4245 First Aid Kit Male Genital Desensitizer Stud 100 Terrasil Itch, Rash and Pain Relief Minnerva II Numb 520 Bactine Pain Relieving CYHOT Cream with Lidocaine Well at WAlgreens Hempvana Maximum Strength Pain Relief Cream Walgreens Anorectal Lidocaine Cream Prilo Patch TopCare Pain Relief Maximum Strength Walgreens Aloe Vera Pain Relieving Instant Burn Relief miaderm-L radiation relief LiProZonePak Burn Jel Plus Revivol Hemorrhoid and Fissure Lidocaine Hydrochloride Injection Physician EZ Use Joint Tunnel and Trigger Kit BenePatch ReCellTis Wound Cream Single-shot Epidural Anesthesia Tray Burn Relief Pain Reliever Well at Walgreens Walgreens Pain Relieving with Lavender Analgesic Harmony Hemp NeuroComfort Pain Relief Gel 500 Lidodan Cream 4% Zeyocaine Ultimate Lidocaine Pain 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80 LM-C Lidocoll Lidozo Topical Pain Patch DermaNumb Tattoo Anesthetic Atelocollagen Implant Lidotrans 5 Pak HAWAIIAN Tropic Meijer Pain Relief TLC Plus Anesthetic G Lydexa 4.12% Harmony Hemp NeuroComfort Pain Relief Spray500 Baciguent Plus Pain Reliever Ont Limencin Western Family Aloe Vera Moisturizing Coralite Odor Free Pain Relief 4224 First Aid Kit Assured Bikini Smooth Cream Advanced DNA Medicated Collection Kit III 4267 First Aid Kit Sj3 Lubricaine 5 4321 First Aid Kit Chi-Myst Synergy Topical Tridacaine II Fruit of the Earth Aloe Vera Cool Blue Banana Boat Sooth-A-caine Spray Gel 4032 First Aid Kit Alocane On The Go Medicated Pain Relief Foot CVS Zcaine Fast Acting Anesthetic Lidocaine Hydrochloride, Hydrocortisone Acetate Nox-A-Sting Coachs First Aid Contains 102 Pieces CBD Clinic Pain Relief - Level 1 4067 First Aid Kit Microvix LP Neurozyl Workvie Roll On Trubrexa Patch ER EmReal Ketorocaine LM Kit THERA CARE 24hrs Lidocaine Patch Prizotral Walgreens pain relieving Totally Fun After Sun Dr Butlers Hemorrhoid and Fissure PF 4064 First Aid Kit Siterol Lignospan Speciale Inj LidAll Pro-C-Dure 2 Kit Lidocaine Patch, 5% Blue Tube Lidopril XR Pain Relief 4% Lidocaine Mamisan Pain Relieving Xylocaine Dental Lidocaine HCl 2% and Epinephrine 1:100,000 4235 First Aid Kit 4247 First Aid Kit Continuous Epidural Anesthesia Tray Neutrogena Anti-itch Moisturizer Lidozen Patch Publix Burn Relief ALOE VERA Curist Lidocaine Can SunBurnt PLUS Lidocaine and Prilocaine Cream 4153 First Aid Kit 4252 First Aid Kit Lidocare Mist QC Cool and Heat Roll-On 7-Select After Sun Lidicaine HCl Pain-Relieving with Aloe Vera Transderm-IQ 4264 First Aid Kit Lignospan Forte Betacaine Gel Will Relieve Roll-On Equaline Lidocaine Burn Relief Leader Lidocaine Anorectal Temporary Pain Relief Spray Restore Lidocaine Pain Relief Cream Smartshield After Sun SIMPLY VITAL HEMORRHOID and ANORECTAL RELIEF Synvexia 4227 First Aid Kit LidoFLEX Elbow, Single Pouch Xryliderm DermacinRx Cinlone-II CPI Veltrix Hemporrhoid CBD PAIN RELIEF Cream 4265 First Aid Kit Regenecare Ha 3-Step First Aid Kit Instant Burn Relief Aloe Extra CVS Ketorocaine L Kit BENGAY Ginger Citrus Maximum Strength Pain Relief Lidocaine Patch Harmony Hemp NeuroComfort Pain Relief Lotion500 Extra Strength AfterTAT SHINGBASE Topical Analgesic Synera Lidocaine 2% and Epinephrine 1:100,000 Diabetic First Aid Gel Cold Sore Treatment Extra Strength Naturally Hl Warming Ice Lidocaine 15% / Phenylephrine HCl 0.25% / Prilocaine 5% Solmara Spinal Anesthesia Tray 1% Gen 7t Naturally HL Extra Strength Hemorrhoid Numbing Good Sense Burn Relief Aloe Lidocaine 4 Percent PLUS Lidocaine with Menthol 4197 First Aid Kit Lt Anorectal Tridacaine III Walgreens Lidocaine Plus Cream LMR Plus PS-3885 Burn Ease, 3.5g Antibiotic Cream Plus Pain Relief for Kids Truu Balance Pain Relief CVS Burn Relief w/Lido 8oz Mlk F4-C Genuine First Aid Burn Antiseptic Pain Relief With Aloe Mega Patch Polysporin Plus Pain Relief Ear Drops 4318 First Aid 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Lidocaine, Camphor Easy Care First Aid Chest - Home and Workshop Point Of Care L2 Lidocort Lipsorex Plus Aprizio Pak 4379 First Aid Kit 4117 First Aid Kit Lidocream Plus Bactine Max GPL Pak CVS Health XL Lidocaine Pain Relief Skullduggery Pain Relief and Skin Protection for Tattoos Small Cuts and Burns ProStat Blood Clotting First Aid Walgreens Burn relief Paraid Burn Ear Pain MD (E007) Footworks Healthy Cracked Heel Cream Menthocin Patch with Lidocaine - Strong Aramark Burn Viadur Deep Pain Relief Lidocaine 4 Percent and Menthol 1 Percent Roll-On Renuu Patch Prolayed 4390 First Aid Kit ManaMed Lidocaine 4% Pain Relieving Gel Patch 4369 First Aid Kit 4090 First Aid Kit Equate Pain Relieving Patches Burn Jel Xylocaine Mpf Omnitrenidol Central Venous Catheter Expanded Kit CidalEaze Polysporin Plus Pain Relief Burn Gel Extra Strength Naturally HL Warming Ice Biotic-Plus Burn First Aid 3 Step First Aid Kit Anestacon ABREVA Rapid Pain Relief Diphen Fruit of the Earth Sun Town City 4373 First Aid Kit PM External Tough Love Pain Relieving Lidomax 5 Zims Max Freeze RR Roll-On for Pain Xylocaine Dental Lidocaine Hydrochloride 2% and Epinephrine 1:50,000 X3 On-the-GO First Aid Burn Relief Spray Inkeeze Original B Numb Cylinder Moxicaine kit Prolida Rectal Care Cream Revivol 4068 First Aid Kit Wound Debridement Kit Jampocaine 2% Viscous Solution Alocane Botanicals Assured First Aid Only Burn 4044 First Aid Kit DentiPatch 4401 First Aid Kit Percutaneous Sheath Introducer Tray Satohap Lidocaine 4% Menthol 1% Pain Relieving Cream Fruit of the Earth Cool Blue Aloe Mist Continuous Relieve Cream with Lidocaine Lidocan BENGAY Tropical Jasmine KARMA RUB Elemental Pain Relief Burn Relief Signature Care Burn Relief Lumbar Puncture Tray 1% Pediatric/infant 4052 First Aid Kit Mueller First Aid Antiseptic 0.4% Lidocaine Hydrochloride and 5% Dextrose Injection FAK Large Office First Aid kit RectaGel HC Quick Numb Simply Numb Endure Equate Hemorrhoid Relief VIVA Patch Cbd4 Freeze Pump 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SUGAR BRANDS Rescue Pain Relief and Recovery Crane Safety Burn Greencaine Blast Lidocaine 2% and Epinephrine 1:50 000 Amino Rip Muscle Pain Relief 4136 First Aid Kit First aid and Burn Lidodextrapine 4151 First Aid Kit Bikini Zone Banana Boat Sooth-A-caine W.moist.aloe V.gel Bikini Zone Medicated CREME Polysporin Cold Sore Ointment Gold Bond Pain and Itch Burnrelief Myelogram Tray 1% Solarcaine First Aid Lidocaine Spray Walgreen Pain Relieving Fragrance Free Jamshidi Menghini Soft Tissue Biopsy Tray Lidocaine 5% Patch Comfortox Lidocaine Dermazyl PainBloc24 Flexi-Stretch Pain Tape Xylocaine Rite Aid Lidocaine Patch XLarge Walgreens Pain Relieving with Turmeric Analgesic Maximum strength Lidocaine Patch Marlido 25 Kit CBDMEDIC Itch and Rash Numquick Topical Analgesic Leva Set with Occlusive Dressing AnaMantle HC 4243 First Aid Kit Itch Relief Max Strength Doctor Butlers Numb It All Cream Arrow Two-lumen Jugular Catheterization Kit MLK F3 Kit 4274 First Aid Kit BurnX Pain Relieving Burn 2% Lidocaine Hci Soothee Patch Aspercreme Lidocaine XL CVS Bacitracin with Pain Relief Paracentesis Tray W Boasberg Catheter Set PRILOVIX Lite myDerm Numbing Roll-On Aspercreme Lidocaine with Eucalyptus Essential Oil Bikini Zone Topical Analgesic Gel Redicare Burn Gel 4098 First Aid Kit After Sun Burn Relief Lidocaine Continuous Spray Watkins Burn Cream Lidocare 03 PAIN RELIEF Gel-Patch MTX Topical Pain 4309 First Aid Kit Lmc Dermatool Hemorrhoidal Dyural LM- C Healthy Wise Pain Relief Lidocaine Patch 4396 First Aid Kit Foot Works Cracked Heel Holy Water Mercy In A Bottle Swiss Navy Endurance Rx Pro Skyn Endurance Delay For Men FAK Care4 Bus and School Yellow ORM D CVS Health Aftersun Aloe Vera Cooling 4338 First Aid Kit Centipaine for Pain Control 4079 First Aid Kit Extra Strength Sunburn Relief Haku Kalima 4106 First Aid Kit Lidocare Arm, Neck, Leg 4311 First Aid Kit 4249 First Aid Kit TheraCare 4% Lidocaine Cream Cannabicool Pain Relieving Lidocaine Roll-On Senstend Hempvana Ultra Strength Pain Relief 4397 First Aid Kit 4327 First Aid Kit De La Cruz Mercurochrome UniShield First Aid Burn 4350 First Aid Kit Steady Freddy 4082 First Aid Kit Comfort EZ Pain Relief Patch POWERECT Lidocaine Male Delay RectaEase Hemorrhoid Relief Cream Mentholatum Lidocaine Ice Emla Cream First Aid Burn Green Compass Reduce Topical Pain Lidocaine Hydrochloride 1.5% and Epinephrine 1:200000 Injection USP Test Dose NeuroMed AR Lidocaine and Prilocaine 4282 First Aid Kit Satohap Lidocaine Hydrochloride 4 Percent Pain Relieving Pentican Sore Relief Medolor Pak Lidocaine and Prilocaine Cream Kit Lidocaine HCl Topical Solution GeriGentle FrostyHeat Pain Relief Patch 4 Lodocaine Back more Indication Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930]. Categories Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Agents that reduce seizure threshold Amides Amines Analgesics and Anesthetics
Anesthetics Anesthetics for Topical Use Anesthetics, Local Anilides Aniline Compounds Antiarrhythmic agents Antiarrhythmics, Class I Antiarrhythmics, Class Ib Antipruritics and Local Anesthetics Antipruritics, Incl. Antihistamines, Anesthetics, Etc. Cardiac Therapy Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (moderate) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2A6 Substrates Cytochrome P-450 CYP2B6 Substrates Cytochrome P-450 CYP2C18 Substrates Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 CYP3A7 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Local Anesthesia Local Anesthetics (Amide) Membrane Transport Modulators Methemoglobinemia Associated Agents Nervous System Neuraxial Anesthetics Ophthalmologicals Otologicals P-glycoprotein inhibitors Peripheral Nervous System Agents Sensory System Agents Sodium Channel Blockers Throat Preparations Vasoprotectives Voltage-Gated Sodium Channel Blockers more ATC-Code S01HA07 D04AB01 R02AD02 C01BB01 S02DA01
N01BB52 C05AD01 N01BB02 more CAS number 137-58-6 
