Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
L-Lysine
Lysine monohydrate
Lysine hydrochloride
LYS
(S)-α,ε-diaminocaproic acid
L-Lysin
Lysina
L-2,6-Diaminocaproic acid
(S)-2,6-diaminohexanoic acid
Lysine acid
6-ammonio-L-norleucine
L-lys
Lysinum
Lysine
Lysine acetate
(S)-lysine
Lysine dihydrate
Brand Names
Travasol
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Aminosyn RF
Olimel 4.4% E
Plenamine
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Periolimel 2.5% E
Olimel 5.7%
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
ProSol
Primene 10%
ProcalAmine
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Effervescent Potassium Chloride
Smofkabiven
8.5% Freamine III
Olimel 4.4%
TrophAmine
Vamin N
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Olimel 7.6% E
Olimel 7.6%
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn II 7% With 50% Dextrose
FreAmine HBC
Nephramine Liq IV
Aminosyn II with Electrolytes in Dextrose with Calcium
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Primene 10%-liq IV
Travasol Inj Without Electrolytes 8.5%
Clinisol
Smofkabiven Extra Nitrogen
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
RenAmin
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Renamin (amino Acids) Injection
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
FreAmine III
Travasol Amino Acid Inj 8.5%
Travasol Inj Without Electrolytes 5.5%
Olimel 3.3% E
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Aminosyn
Smofkabiven Electrolyte Free
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
HepatAmine
20% Prosol
Aminosyn-PF 10%
Clinimix E
Kabiven
Clinimix
Aminosyn II in Dextrose
Novamine
Aminosyn II and Dextrose
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn Sulfite Free
Aminosyn II 5% Inj
Travasol Amino Acid Inj 5.5%
Aminosyn-PF
Travasol E
Aminosyn 3.5% M
Vamin 18 Electrolyte-free
Aminosyn HF
Aminosyn-PF 7%
Aminosyn 5%
Olimel 5.7% E
Aminosyn II
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn II In Dextrose Injection
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Essepna
Premasol - sulfite-free (Amino Acid)
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Xyzmune
Aminosyn 8.5%
Lysakare
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Perikabiven
Aminosyn II 8.5% Injection
Aminosyn 10% W Electrolytes
Nutrineal Pd4
Synthamin
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn II 8.5% With 50% Dextrose
NephrAmine
Aminosyn RF Injection
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Primene
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Smofkabiven Peripheral
Aminosyn II 7% Injection
Hepatasol
Imubolic
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Aminosyn II 7% With 10% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Aminosyn II 10% With Electrolytes
Aminosyn 7%
Aminosyn 8.5% Injection With Electrolytes
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Aminosyn II with Electrolytes
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682