Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
L-Lysine
Lysine acid
Lysine
L-Lysin
Lysine dihydrate
L-2,6-Diaminocaproic acid
L-lys
(S)-lysine
(S)-α,ε-diaminocaproic acid
Lysinum
6-ammonio-L-norleucine
Lysine monohydrate
Lysine hydrochloride
Lysina
(S)-2,6-diaminohexanoic acid
LYS
Lysine acetate
Brand Names
Smofkabiven Extra Nitrogen
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Olimel 3.3% E
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II with Electrolytes
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
TrophAmine
Clinimix
Aminosyn Sulfite Free
Synthamin
20% Prosol
Aminosyn II 7% Injection
Smofkabiven
Perikabiven
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Renamin (amino Acids) Injection
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Premasol - sulfite-free (Amino Acid)
Aminosyn II 8.5% Injection
Aminosyn 5%
ProSol
Essepna
Aminosyn 8.5% Injection With Electrolytes
Clinimix E
Aminosyn II 7% With 50% Dextrose
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn-PF 7%
Olimel 7.6%
Olimel 5.7% E
Aminosyn-PF 10%
Primene 10%-liq IV
FreAmine III
Novamine
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Travasol Amino Acid Inj 8.5%
Smofkabiven Electrolyte Free
Travasol E
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Hepatasol
Plenamine
Smofkabiven Peripheral
Effervescent Potassium Chloride
Aminosyn II In Dextrose Injection
RenAmin
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Aminosyn II 5% Inj
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
ProcalAmine
Aminosyn 8.5%
Aminosyn II and Dextrose
Aminosyn 10% W Electrolytes
Aminosyn II in Dextrose
Primene
FreAmine HBC
Travasol
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Nutrineal Pd4
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn II with Electrolytes in Dextrose with Calcium
Aminosyn-PF
Vamin N
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Aminosyn RF Injection
Kabiven
Aminosyn HF
Nephramine Liq IV
Olimel 7.6% E
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Olimel 4.4%
Aminosyn II
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Travasol Inj Without Electrolytes 8.5%
Aminosyn II 8.5% With 50% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Aminosyn
8.5% Freamine III
Aminosyn II 7% With 10% Dextrose
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Aminosyn II 10% With Electrolytes
Aminosyn 3.5% M
Clinisol
NephrAmine
Lysakare
HepatAmine
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Imubolic
Xyzmune
Aminosyn RF
Smofkabiven Extra Nitrogen Electrolyte Free
Primene 10%
Olimel 5.7%
Vamin 18 Electrolyte-free
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Periolimel 2.5% E
Aminosyn 7%
Travasol Inj Without Electrolytes 5.5%
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Travasol Amino Acid Inj 5.5%
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Olimel 4.4% E
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
