Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
(S)-α,ε-diaminocaproic acid
6-ammonio-L-norleucine
Lysine hydrochloride
Lysina
Lysine acetate
Lysine monohydrate
L-lys
Lysine dihydrate
Lysine acid
Lysine
(S)-2,6-diaminohexanoic acid
L-2,6-Diaminocaproic acid
L-Lysin
L-Lysine
Lysinum
(S)-lysine
LYS
Brand Names
HepatAmine
Aminosyn II 7% With 10% Dextrose
Aminosyn II 7% With 50% Dextrose
Vamin 18 Electrolyte-free
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Aminosyn II with Electrolytes in Dextrose with Calcium
Travasol Amino Acid Inj 8.5%
Aminosyn-PF 7%
Primene
Aminosyn II 5% Inj
Premasol - sulfite-free (Amino Acid)
Aminosyn 7%
Aminosyn 3.5% M
Olimel 4.4% E
Aminosyn 10% W Electrolytes
Smofkabiven Peripheral
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Olimel 7.6%
Novamine
Periolimel 2.5% E
Smofkabiven Electrolyte Free
Hepatasol
Aminosyn II 8.5% Injection
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Aminosyn HF
Aminosyn II with Electrolytes
Smofkabiven
Synthamin
FreAmine HBC
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Clinisol
Aminosyn RF Injection
Nephramine Liq IV
Aminosyn II 10% With Electrolytes
Aminosyn II 7% Injection
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
TrophAmine
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Clinimix E
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Olimel 7.6% E
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Olimel 5.7%
Kabiven
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn Sulfite Free
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Aminosyn II
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Aminosyn 5%
Olimel 3.3% E
Aminosyn-PF 10%
Nutrineal Pd4
Plenamine
Travasol Inj Without Electrolytes 8.5%
Aminosyn II and Dextrose
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Primene 10%-liq IV
Olimel 5.7% E
20% Prosol
Xyzmune
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn-PF
Aminosyn II in Dextrose
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn 8.5% Injection With Electrolytes
NephrAmine
Travasol
Essepna
Clinimix
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
ProcalAmine
Lysakare
FreAmine III
Travasol Inj Without Electrolytes 5.5%
8.5% Freamine III
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn II In Dextrose Injection
Travasol Amino Acid Inj 5.5%
Aminosyn
Aminosyn II 8.5% With 50% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
RenAmin
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
ProSol
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Aminosyn 8.5%
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Imubolic
Renamin (amino Acids) Injection
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Vamin N
Aminosyn RF
Travasol E
Olimel 4.4%
Perikabiven
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Primene 10%
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Smofkabiven Extra Nitrogen
Effervescent Potassium Chloride
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682