Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
Lysine acetate
Lysinum
LYS
(S)-α,ε-diaminocaproic acid
(S)-2,6-diaminohexanoic acid
L-lys
L-Lysin
Lysine monohydrate
Lysina
6-ammonio-L-norleucine
Lysine dihydrate
Lysine acid
L-2,6-Diaminocaproic acid
Lysine hydrochloride
L-Lysine
(S)-lysine
Lysine
Brand Names
Essepna
Aminosyn 10% W Electrolytes
Olimel 7.6% E
Aminosyn II in Dextrose
HepatAmine
Aminosyn II
Olimel 5.7% E
Aminosyn Sulfite Free
FreAmine III
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Travasol Inj Without Electrolytes 5.5%
Primene
Aminosyn II 10% With Electrolytes
Smofkabiven
Smofkabiven Extra Nitrogen
Aminosyn II 8.5% With 50% Dextrose
Aminosyn II In Dextrose Injection
TrophAmine
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Aminosyn-PF
Aminosyn II 7% Injection
Aminosyn II 7% With 10% Dextrose
Kabiven
Perikabiven
Travasol
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II 5% Inj
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Aminosyn-PF 10%
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Vamin N
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn RF
Smofkabiven Electrolyte Free
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Olimel 3.3% E
Lysakare
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
NephrAmine
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn 8.5% Injection With Electrolytes
Clinimix E
Aminosyn II with Electrolytes in Dextrose with Calcium
Novamine
Effervescent Potassium Chloride
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Clinisol
Aminosyn 8.5%
Aminosyn 5%
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
20% Prosol
Aminosyn II and Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Primene 10%
Hepatasol
Renamin (amino Acids) Injection
Smofkabiven Peripheral
Xyzmune
Aminosyn
ProSol
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Olimel 4.4%
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn II with Electrolytes
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
8.5% Freamine III
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Travasol Amino Acid Inj 5.5%
Aminosyn II 7% With 50% Dextrose
Nephramine Liq IV
Aminosyn HF
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Premasol - sulfite-free (Amino Acid)
Plenamine
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Synthamin
Clinimix
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
FreAmine HBC
Aminosyn 3.5% M
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Primene 10%-liq IV
Vamin 18 Electrolyte-free
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
ProcalAmine
Aminosyn RF Injection
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Olimel 7.6%
Aminosyn-PF 7%
Olimel 4.4% E
RenAmin
Nutrineal Pd4
Aminosyn II 8.5% Injection
Aminosyn 7%
Travasol Amino Acid Inj 8.5%
Olimel 5.7%
Travasol E
Imubolic
Periolimel 2.5% E
Travasol Inj Without Electrolytes 8.5%
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682