Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
LYS
Lysine hydrochloride
Lysinum
Lysina
Lysine dihydrate
6-ammonio-L-norleucine
Lysine monohydrate
L-lys
(S)-α,ε-diaminocaproic acid
Lysine
Lysine acetate
(S)-lysine
L-2,6-Diaminocaproic acid
L-Lysine
L-Lysin
Lysine acid
(S)-2,6-diaminohexanoic acid
Brand Names
Aminosyn II
Travasol Amino Acid Inj 8.5%
Aminosyn RF Injection
Aminosyn II 8.5% Injection
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Aminosyn 5%
Aminosyn HF
Clinisol
Aminosyn
Plenamine
Smofkabiven Extra Nitrogen Electrolyte Free
Travasol Inj Without Electrolytes 5.5%
Imubolic
Olimel 5.7%
Olimel 7.6%
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn II 7% With 10% Dextrose
Primene 10%-liq IV
ProSol
Travasol Inj Without Electrolytes 8.5%
Premasol - sulfite-free (Amino Acid)
Smofkabiven Electrolyte Free
Aminosyn II In Dextrose Injection
Aminosyn RF
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Xyzmune
NephrAmine
Aminosyn II 8.5% With 50% Dextrose
Travasol E
Olimel 5.7% E
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Aminosyn II 10% With Electrolytes
Lysakare
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Nutrineal Pd4
Hepatasol
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Aminosyn Sulfite Free
TrophAmine
Travasol Amino Acid Inj 5.5%
FreAmine HBC
HepatAmine
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Aminosyn 8.5% Injection With Electrolytes
Nephramine Liq IV
Aminosyn 10% W Electrolytes
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Aminosyn II and Dextrose
Renamin (amino Acids) Injection
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
8.5% Freamine III
Aminosyn-PF 7%
Aminosyn 7%
Essepna
Aminosyn II 7% With 50% Dextrose
Clinimix
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Olimel 4.4% E
Primene
Periolimel 2.5% E
Travasol
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Aminosyn II in Dextrose
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Smofkabiven
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Smofkabiven Peripheral
Smofkabiven Extra Nitrogen
Aminosyn II 7% Injection
Olimel 3.3% E
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Effervescent Potassium Chloride
Olimel 7.6% E
Aminosyn 8.5%
Synthamin
20% Prosol
Vamin N
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Aminosyn-PF 10%
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Kabiven
Perikabiven
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Novamine
FreAmine III
Primene 10%
RenAmin
Clinimix E
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn II 5% Inj
ProcalAmine
Vamin 18 Electrolyte-free
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II with Electrolytes
Olimel 4.4%
Aminosyn-PF
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Aminosyn II with Electrolytes in Dextrose with Calcium
Aminosyn 3.5% M
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682