Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
L-2,6-Diaminocaproic acid
(S)-α,ε-diaminocaproic acid
Lysina
Lysine hydrochloride
Lysine monohydrate
L-Lysine
(S)-2,6-diaminohexanoic acid
Lysine acid
LYS
L-Lysin
(S)-lysine
Lysinum
Lysine
6-ammonio-L-norleucine
L-lys
Lysine dihydrate
Lysine acetate
Brand Names
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Aminosyn-PF 10%
Primene 10%-liq IV
Aminosyn II 10% With Electrolytes
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Aminosyn II In Dextrose Injection
Clinisol
Xyzmune
Aminosyn-PF
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
FreAmine HBC
Essepna
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Travasol Inj Without Electrolytes 8.5%
Aminosyn II in Dextrose
Aminosyn 7%
Clinimix E
Aminosyn II 8.5% Injection
Aminosyn-PF 7%
Periolimel 2.5% E
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Olimel 5.7% E
Olimel 7.6%
Smofkabiven
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Vamin 18 Electrolyte-free
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn 5%
Aminosyn II 5% Inj
FreAmine III
Nephramine Liq IV
8.5% Freamine III
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Aminosyn II 7% With 50% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Vamin N
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn RF
Smofkabiven Peripheral
Olimel 5.7%
Smofkabiven Electrolyte Free
Lysakare
TrophAmine
ProSol
Aminosyn II 8.5% With 50% Dextrose
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Travasol Amino Acid Inj 8.5%
Renamin (amino Acids) Injection
Effervescent Potassium Chloride
RenAmin
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Perikabiven
Aminosyn II 7% With 10% Dextrose
Aminosyn II 7% Injection
Aminosyn HF
Synthamin
HepatAmine
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn RF Injection
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Smofkabiven Extra Nitrogen Electrolyte Free
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Travasol Amino Acid Inj 5.5%
Aminosyn II
Premasol - sulfite-free (Amino Acid)
Clinimix
Imubolic
Aminosyn II with Electrolytes
Travasol E
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Olimel 3.3% E
Nutrineal Pd4
Novamine
NephrAmine
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn Sulfite Free
Aminosyn II with Electrolytes in Dextrose with Calcium
Hepatasol
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn 10% W Electrolytes
Aminosyn II and Dextrose
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Aminosyn 3.5% M
Primene 10%
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
20% Prosol
Travasol
ProcalAmine
Plenamine
Smofkabiven Extra Nitrogen
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Aminosyn 8.5%
Aminosyn 8.5% Injection With Electrolytes
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Primene
Travasol Inj Without Electrolytes 5.5%
Olimel 4.4%
Olimel 4.4% E
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Aminosyn
Kabiven
Olimel 7.6% E
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
