VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	approved nutraceutical vet_approved investigational
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiamine chloride Vitamin B1 Aneurin thiaminium Thiaminum Thiamine mononitrate thiamine(1+) ion Thiamine Thiamine hydrochloride Thiamin Antiberiberi factor Tiamina thiamine(1+)
Brand Names	Virt-Nate DHA B Complex With C 550mg Stress B Complex With C, E & Iron Escavite Lq VitaXyme MultiVitamin, Iron and Fluoride Drops B Virol Lexazin Neo-bex Children's Chewable Multi Vitamins Niva-Plus B-1 Caps 500mg Stress B&c Tab Phytofortis + Calcium A-D Thiamine HCl Inj 100mg/ml Vita Vim With Beta Carotene-caplet Vitaday Junior Tab Chela-chromium 200 Nephron FA Multi Plex I - Tab Avon Vitadvance Multi-kids Complete Complexe B 75mg Essential Vitamins and Minerals Glyco Plus Ect Senior Multi One Renate DHA Complete Mega B Venexa FE Vitamin B1 Tab 100mg USP Gestamine Comprimes Cc II Stress B-complex Plus Iron With Vitamins C&e Azesco Kid's Choice Children's Chewable Vitamins - Tab Vitrexyl Concept DHA Balanced B-50 B-complex Vitamins Tab Prena1 Plus Vitamin B Tablets Nutri-Tab OB plus DHA SetonET-EC Tender Age Multi Vitamins T.R.I. B-plex Src Osteo-force Essential B Tablets Hill.vite Keylosa Vitafol One Supravite Stress Avec Vit E Et Fer Vitranol Fe Active OB Irospan 24/6 B-complex Tablets Supravite 10ml Ampoule Gtf-vitamin-minerals & Pancreatin Tab B-100 Caps Children Choice Multivit Chewable Tab Bal-Care DHA Alsimine W Vitamins A D Surbex-500 With Zinc Body Rox PR Natal 430 ec Card-floe II Tab Multiple Vitamins Plus Iron for Women Multitabs Tricare Prenatal DHA One With Folate Vimeral Tab B Complex With C 300mg Tab hormaSAN forte Vitamin B + C Cap Revit Plus Cap Paramettes Multivits Plus Iron Tab (teens) Mini-B Tab L.C. Supplement Viamon Ampoules Et Comprimes Prenatvite Plus Stress Formula Multivitamin Tablets USP Prenatvite Complete Stressmates V & M Vitamin and Mineral Supplement Complete Multivitamins and Minerals for Children N.E.U. Complex Allbee With Vitamin C Cap B Complex Tablets One-A-day Advance Men's Enrich Core Pack - Children Vitamin and Mineral Supplement High Potency Multivitamins & Minerals Caplets Vitafol Ultra Surbex 500 Filmtab Cavan Prenatal Chewable Multiple Vitamins for Children Deriton Balanced B50 Complex Elite OB Prenatal Multivitamin Hi Potency Multi Tab DuetDHA Balanced Innersource Tab Multicaps Paramettes Chewable Multivits With Iron Tab Pregvit Stress Formula Tab B-50 Complex Tab Men's Multi Master Formula Multi Vitamin and Mineral vitamin Prenara Vitamin and Mineral Supplement - Liq Liqui B Complex Glyco Lite Ect Virt Nate Multi Rol Vitamin B Complex 100 B Complex With C 300mg Children's Chewable Multi-vitamin Complete With Minerals Prenatal Vitamins Plus Low Iron Flintstones Multiple Vitamins Luna Vitamin and Mineral Bar for Women Vita B Complex Tab Genicin Vita-S Folet DHA CitraNatal Rx Multiple Vitamins Plus Iron - Tab Liqui Vita Mega Plex III - Pck One A Day Advance Fem Paramettes Adults Choice OB DHA Complex-75 Marnatal F Multi-Vit with Fluoride and Iron Childrens Chewable Vitamin Tab Stress Tab With Zinc, Copper and Vitamin E Super Stress Capsules VP-Vite Rx Complex 5 - Pwr NataFort PNV-First Am Caps One A Day Multiple Vit W Minerals One Tablet Daily Mens Formula Davimet-M Thiamine Vol-Nate Iron Folate Plus Viva CT Prenatal Multivitamin with Fluoride Supravite Pour Enfants Timed Release B-complex 100 TriAdvance Multi Plex II - Tab TriStart DHA Children's Multivitamins Swiss One Thiamine HCl Injection - Liq 100mg/ml Corvite MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Floriva Balanced B100 Obstetrix EC Kids Stuff Tablets Efferlife Multivitamins and Minerals Forty Plus Vitamin Supplement Se-Natal 19 Chewable Vita Balance 2000 Trinatal Ultra Biovim Tab PureVit DualFe Plus Twin Ultra Liquid Grape Flavor Multi B Multi-Vitamin Drops with Fluoride and Iron K.L. Vitamin-mineral Complexe B Compose 75 Vitamine B1 Tab 100mg USP Xyzbac G Allbee C 800 Tab Flinstones Multiple Plus Iron Supravite Bouteille 250ml RenaPlex Sopalamine 3b Plus Stress B With 1000 Mg Vitamin C One-A-day Advance Fem - Tablets Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Multi-12/k1 Pediatric Twin G.F. Powder Vanilla Flavor Tini-cal Ampoules Sopalamine/3b Tab Renal Caps Dialysis/Stress Vitamin Supplement Multiple Vitamin Plus Minerals Tab Glyco-aide Tab Revitalize Multi-vitamin and Mineral Complex Stress Formula Multi-B Comp + 500mg Vit C Cap Swical-energy-2 Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Prenate Elite Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Multiple Vitamins Plus Iron Tab Prenatal and Post Partum Supplement Thiamine Hydrochloride Inj 100mg/ml Vtb Vitamin and Mineral Supplement Hi Potency Balanced B-100 Complex - Tab Prenatal Vitamin and Mineral Supplement Tab Vitamin B Cpd W Vit C Tab Thiamine HCl 100mg W C 20mg Vp-heme Ob DHA Prenatal Vitamin and Mineral Supplement Thrivite Rx Fortistress Tab Bev 29 Tab Virt-C DHA Gemvites Jr Tab Chewable Formula Hh Multi 12 Injection Natal PNV Prefera OB plus DHA Somavit Brand Vitamins and Minerals Complex Triveen-Duo DHA Zatean-Pn Vital-D Rx Strovite One Caplets Livita Adults Super Stress Mega B Plus 1000mg Vit C Tab Poly-Vite Pediatric Oral Solution CitraNatal Essence Meplex T 750 Vitafol Caplet Formula Lf Integra Plus Vasculine Maxum Multi-vite Chew.multiple Vits.with Extra C for Children Flintstones W Extra C Tab Mvc 9 Plus 3 Inj Prenatal Supplement - Tab Only One - Tablet PNV Prenatal Vitamin Centratex One Per Day Vitamin and Mineral Dietary Supplement Prevital Tab Dialyvite with Zinc MultiVitamin Drops with Fluoride and Iron Vita-B Swiss One Multivitamin and Mineral Caplet Vol-Care Rx Davimet with Iron Complete One-A-day - Tab Nephrocaps-QT Advanced B & T Formula B1 Tab 100mg SetonET Stress B & C Caplet Multi Spectrum - Tablet bioJET PreTAB Multivitamins and Minerals Tablets Envirocomplex B Complex W Vit C W Non-med Yeast&liver Tab Dermamed Nutrition for troubled skin Orange Flavored Crystal Chews Tab Multitam Novel Vita Dialyvite Virt-Bal DHA Plus Balanced B 125 Srt Children's Chewable Multiple Vitamins (chewable Tablets) Hi Potency B52 B Complex Tab Sibergin B - Cap Multi-Vitamin NeuroBion Folivane-Plus with Ascorbic Acid Precursors Methaver Vitachrom Gc Pregvit Folic 5 Distilpure Msm Vita-B-75 Cap Materna-tab Iron, Vit & Min Supp WesNate DHA Se-Care Conceive Women's Biomultiple Vitamin and Mineral Supplement Multi-Vitamin Fluoride and Iron Drops Materna Cavan-EC SOD DHA B1 400mg Ctr Tab Chewable Multivitamins Alkadrenergy Tablets Cavan Alpha Beminal With C Fortis Pws Folika-V Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Onccor Vitamin B1 Tab 2mg USP M.V.I.-12 ahoSAN Infuvite Pediatric PR Natal 400 ec Prenatal Plus Multivitamin Plus DHA MiniCaps Neomultivite Floriva Plus Neo-vites & Minerals Tab Neonatal19 Quflora Pediatric P.R.O. Complex Fortamines-10 Comprimes Bal-Care DHA Essential Dia-vite Lipotropic Ctr Multi 1000 Multivitamins PM Caps Supravite Stress Avec Vit E Tonicol Et A-D-C Ampoules/comprimes PNV Tabs 29-1 Poly-Vi-Sol Zoo Chews Poly-Vite/Iron Oral Solution Harvest Of Values All B Complex Tab Revit Multi-vitamins and Minerals Multi-vitamins With Minerals Prenatol-M Vitamin B1 Classic Swiss One 10 Multivitamin and Mineral Tab Multi-Vitamin Fluoride Drops WesCap-C-DHA Adult Infuvite Multiple Vitamins Chewable Multiple Vitamins Tab CitraNatal 90 DHA Neo-bex Injectable Tricare Prenatal Compleat Virt-PN Multi-vitamin Dietary Supplement P.N. Vitamin-mineral Drink Mega Vitaminerals Prenatal Plus Iron Multiple Vitamins and Minerals Tab Kenwood Liquid Supplement Chewable Multiple Vitamins Plus Extra C Kanga-kid Multi-vitamin & Mineral Vita-worth B-complex Tablets vitaMedMD One Rx Vasodyn Tab Orti B Paramettes Syrup Duet DHA Multiple Vitamins With Minerals Tablets Timed Release B-complex 50 Vitafol Fe Plus E.S.T. Complex Men's B With C 500 Cap Stress Formula Vit B With C Complex Supravite C 1000 Synergistic Manganese Cap Folika-T Multitol-M Xyzbac Permathene-12 - Caplet Multi Vitamines - Liq Neonatal DHA Olympian Multi Vit Plus Minerals Tab Everyday Multiple Vitamins With Iron Active FE Vitamines Pour Bebes Et Enfants CitraNatal Assure Gesticare DHA Multivitamins and Minerals - Complete Vyqua Quflora FE Pediatric Drops Supplement De Multivitamines Infusion Arome Fruits Rouges Kanga-kid Vitamins & Iron Prenatal, DHA Children's Vitamins W Iron Chewable Se-Natal Super Kids Chewable Multivitamin Multimineral (chewable Tablets) MultiVitamin with Fluoride Drops Multivitamins and Minerals With Betacarotene Tablets Vitamin B-1 100 Mg Tablets Vol-Plus Escavite D Leritone Junior Vitogen B Stress C Vit E Zinc & Cop Prenatal Formula Tab Virt-Nate B-100 Complex Tablets Men's 50+ Vita B + C 500 Tab Natavite Multivit Et Fer Ampoules Et Comprimes Nephrocaps Provida OB Twin Ultra Liquid Fruit Punch Flavor Children's Chewable Tab PreQue 10 Right Choice A.M. Multi Formula - Caplet Bugs Bunny and Friends Multiple Vitamins New Chapter's D'adamo 4 Your Type Multiple for Type O Super Charged Energy Vinacal Multivitamines Et Mineraux Junior Regulier Vitafer - Liq Multiple Vitamins W Minerals Tab NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vita-vim With Beta-carotene - Tab Vitramyn Flintstones Multiple Vitamins Tab Vitalife - Capsule Vitamine B1 100 Mg - Tablet Cavan Folate OB Ventrixyl Obstetrix DHA Combo Pack TL-Care DHA HemeNatal OB Prenatvite Pretrate Vitamin B Complex 50 Stress Vitamin B With C Complex Tablets Formula F L W Tonimol Cap Liq Lipovite INATAL Ultra Multivitamines Pour Enfants (chewable Tablets) Vit B Complex Plus Vit C 550mg Chewable Multiple Vit Plus Iron for Children Vege 1 Daily Tab Hemocyte Plus Stress Tab With Iron and Vitamin E Omega-3 Rx Complete O-Cal Prenatal Vitamin For Kids Only Chewable Multivitamins - Tab Stress B Complex With C, E and Iron Tab Ultra Hr Vitamin B Complex W C Tab Quflora FE B-complex 100 Children's Chewable Multiple Vitamins - Tab Childrens Chewable Multiple Vitamins Plus Fe Pregnancy Multivitamin CitraNatal DHA Children's Chewable Multi-vitamin Natal-V RX Multi-vitamin/Multi-mineral Multivitamins and Minerals for Young Men Childrens Chewable Multiple Vitamins Tab Iron Polysaccharides Folic Acid DHA Liqui Infant Vitamins Prenatal Vit B Complex Ctr Hyporyl - Tab 50 Plus Vitasure Tendera-OB Multi Vite Liq Junior Multiple Vitamins W Iron Tab Ultra Enerforce Zoo Chews Plus Iron Thiamine Hydrochloride Injection USP, 100mg/ml Thiamine HCl Tab 100mg Childrens Chew Multi Vitamin Tab Childrens Chewable Multivitamins W Iron Floravit - Syr Vit B1 Ctr Srt 100mg Children's Chew Multi & Min Tab Lorid Multivit with Fluoride One A Day Advance Adults 50+ Vege Swiss One Multivitamin W Chel Mins Tab Multivitamines Plus Fer Pour Enfants (chewable Tablets) Vyo Cylate - Pwr Zintrexyl-C D'pantothenic Acid-B1-B2 Tab Stress Forte Plus Lipotropic Factors Kanga-V Multivitamins & Minerals Twin Ultra Liquid Orange Flavor B6 Plus Tab Swiss One Multi Vit & Chel Min Tab Timed Release Vita-vim Srt Multi-vitamins THIAMINE HYDROCHLORIDE injection, solution Select OB Vitamin B Compound Tab Usana Megavitamin Tablets - Tab Ellis Tonic Multi Vitamin - Mineral Nutra-clear Formula O.C. Super Pantoplex Vitrexate FE O-Cal FA multivitamin Garfield Chewable Multivits Plus Iron Tab Fem Time Tab Hemarexin Amp Xvite Children's Chewable Multivitamin Complete With Minerals Multivitamin with fluoride Vitaphil 90 DHA Isotonix Multitech Vitamin Mineral Supplemen Ziphex PreferaOB DaVITE Pnv-VP-U Corvite Free NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Maxine Vitamin and Mineral Supplement Chromease Tab Balanced B-complex Vit + Vit C&e Tab Ribotin-E Multiple Vitamins Multiple Vitamins Tab Vol-Tab Rx Swical-energy 3e Age B Plus C 300 mg Provida DHA Vitamines Et Mineraux RE Nata Prenate Star Multivitamin with 0.25 mg Fluoride Chewable Multiple Vitamins Plus Iron Tab Multra With Iron Nitro Vites - Tab Virt Vite GT Acti-MN + B1 + C Caplet Dexatran P.N.P. Vitamin Drink Dynam Ampoule Et Tablet Totalvit Plus Vit-HA Multi Vitamin and Zinc Supplement Vitafol OB Caplet OBTREX DHA Combo Pack Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Formula Gm Stress B Complex With C,e, Zinc and Copper Z Bec Tab Total Living Concepts Formula One - Tab Cedevita Plus Vitamin Supplement Daily Balance Tab PROTECT IRON Liquid Vitamin B1 100mg Kaydia Patch B Stress C + Iron & Vite Vita-Pac Ferra Naka Plus Vitamins Prenatal Vitamin and Mineral Supplement -tab Re Ob 90 DHA CompleteNate Chewable Twin Ultra Liquid Lemon-lime Flavor Pregvit Folic 4 Sun-rype Vitaburst Vigo Multivitamins Drops/lozenge PNV Ferrous Fumarate Docusate Folic Acid For-2 Childrens Chewable Multivitamins B Complex 500 Tab Vitamine 110 Liq Multi Vitamin Drops with Fluoride Enviroflex - Tab Penta-thion Pwr Nutra-Z Premium Prenatal - Tablets Vitamin B Complex + C 600mg Tab Prenatal Plus Vitamins Phytovim Cap Nutri-Tab OB Multi - N.T.O.x Formula - Tab Synergistic Manganese Capsules Vitamin B-1 Thiamine HCl 100mg Mega Plex IV - Pck RenaPlex-D OB Complete DHA Pro His Mint tensioSAN Fortaplex Inj B Complex W Vitamin C Fortis Cap Bugs Bunny Chew Multi Vit Plus Iron Formula Pro-B Vitaflex Dietary Suplement Renate Prenatal Vi-min Multiple Vitamins & Minerals Tablets Vitamines Et Mineraux Enfants 970 Hi Potency Stress B Tension With C Multivitamins and Multiminerals Formula Regular Tablet Multra Plex Hemarexin Liquid and Drinkable Ampoules Stress Ctr Srt WesTab Plus G.A.S. Complex Vinate AZ Bev B-150 Iberet 500 Oncovite PreferaOB plus DHA Folica-V 50 Plus Multiple Vitamins & Minerals 24 Multivitamins + Minerals Dexifol Antlerviron Multivitamin Multivitamin & Multimineral NovaFerrum Multivitamin with Iron Pediatric Drops Doctor's Choice Brand for Men One Daily Vitamin and Mineral Dietary Supplement Multi-Vit with Fluoride Somarexin and C 1000 Ventrixyl Fe Original Bioscal Forte Multi-vitamin Supplement Capsules B-complex-50 Tab Inatal Advance Vitogen B Stress C600 Wellness Formula Dexatrim Tablets Medi Msm (methyl Sulfonyl Methane) TL-Fluorivite NataChew B-100 Hi Potency B Vitamins Tab PrePLUS Vitamin B Complex Plus C 300mg Timed Release Duet DHA 400 Timed Release B Complex 100 Srt Select-OB Plus DHA Prenatal Supplement Plus DHA Flintstones Multiple Vitamins Plus Iron Multi-kid Stress Tab Venexa Multi Enfants Tab Multi Vitamin Drops with Fluoride and Iron Folitin-Z Vitranol Childrens Multiple Vit and Min Chew Tab Prim - Royal P.M.T. Multivitamins for Children Vitamin B Compound W Vit C 250mg Tab Multiple Vitamin Tab Vita-vim - Tab Natalvirt Ca Vital Be-100 Rocky Mountain Multiple Vit and Min Mega Tab Polymine Avec Zinc Et Cuivre Thiamine HCl Tab 50mg Multi-11 Vitamin B-Complex Duet DHA 400 ec Prenatryl Hypo Vites Tab Zalvit L.G.I.T. Vitamin B1 100mg Tablet Stress Formula B 50 Capsules Escavite B Plus C 300mg Timed Release Multi-Vitamin with Fluoride Multivitamines Et Mineraux WestGel DHA Mega 13 Multivitamin Formula Vitamin B Compound With Vitamin C Fortis Capsule Dtc FloraFol Ply Vi Sol Chewable Tab Multivitamins and Minerals for Women Complete-RF Prenatal Moms Choice Rx Multi Pro Ultimate Tab Everyday Multiple Vitamins Prenatal Plus B-50 Hi Potency B Vitamins Tab Multipack II Animal Shapes Cavan Heme OB Children's Chewable Multivitamin and Multimineral Lipo-B-C Tab M.V.I. Pediatric Multi II IV Vi Tab B Complex Plus C 300mg Tab Multiple Vitamins With Iron Tablets Corvita Feminique W Iron and Calcium Tab Nutrol-B-complex Prenatal Vitamins Plus B-Combo PureFe Plus Vita-amine Cap 100mg Multi Vitamin & Minerals Multi-Vit-Flor Phytoplex B Liq Multi Vite Liq Adult Allbee With C 550 Cap Multinate DHA Extra Multivitamin Drops with Fluoride Daily-Vite Bewon Elixir 0.05mg/ml Low Potency B Complex Tab Palm Springs Multvit and Min Tab Formula Fm Vitamins & Minerals Tab OB Complete Petite PNV-Select Mangadyn Vitafant Vitamin B Complex Tab RayaVit Betaxin Liq 100mg/ml Mega-vim 75 With Beta-carotene - Tablets Children Choice Multivitamin W Iron Chew Tab Multivitamins W Minerals Extra Strength Trinatal GT Vc II Gynedyn Tab Vitrexate Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA B-complex Tab Preplus MultiVitamin with Fluoride Chewable Trinatal Rx 1 Viva Kids - Tab Virt-Tabs Myhephron Dialysis and Stress Supplement Dialyvite Supreme D Supravite Stress Avec Vit E Cuivre Et Zinc Tricare Prenatal 2-part Daily Prenatal Vitamin System B-plus - Tab Balanced B-50 B-complex Vitamins, Timed Rele C-force PreNatal 19 Vitaday Tab Fizz Multivitamins for Kids W C Loz Tandem OB VIL-Rx Balanced B-100 B-complex Vitamins Tab Children's Chewable Multiple Vit.plus Iron Women's Formula Natalvirt 90dha Formula Gly Childrens Chewab Vitamin W Chel Minerals Cavan Folate DHA C-Nate DHA DuetDHA Complete Super Vitalex Ampoule Buvable Vitazyme Alertonic Vitamin B1 100 mg C-B Complex Gtf Support Caplet Nata Komplete B 6 Plus Paramettes Chewable Multivitamins Plus Iron Toni Com Liq MultiVitamin with Fluoride M-Natal Plus Maxi 10 Tab Folivane-OB Vitafol Plus B50 B Complex Tab Multi Vitamin, Iron and Fluoride B50 Complex Hemarexin Tab Cda-21 Vitamins With Non-medicinal Probiotic Complex Mebolic Multi Nt-OX Revit Tab WesNatal DHA Complete Multinate DHA Complete Multivitamins and Minerals Tablets Timed Release Appedrine M.V.I. 12 Diaplex Tricare Prenatal Vita-Rx Diabetic Vitamin Foltabs Prenatal Dialyvite 5000 Poly-Vitamin with Fluoride Multi Vitamin with Fluoride Vitamin B Compound W C Tab 500mg Virt-Advance TL-Folate B Complex 50 Vitamin Cap PureFe OB Plus Beminal 500 Tab Poly-Vi-Flor Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Super Vita Vim Multivitamins and Minerals Central-vite 18 Essential Children's Vitamins Chewable Animal Shapes w/Iron Chewtabs Multi Vitamin-mineral Formula Twin Opti Pwr Amladex B Complex 50+ Caplet Vitamin B Complex 100 Tab Vitamines Et Mineraux Comprimes Formula D.S. Adeks - Dps Reaphirm Plant Source DHA Vita Plex Tab Prenatrix B-complex With Vitamin C, Biotin, Folic Acid Protect Plus SO 60 Zeldana Multivit-liq Childrens Chewable Vitamins Multi-vitamines Enfants Comprime Orifer F Fibrik Multi Vitamin Drops with Fluoride with Iron B Totum 500 Multi Vitamins & Minerals Phytopure Milltrium Senior Vitamin and Mineral Supplement Livron Plus Tab Women's Change Formula Thiamine Hydrochloride Inj 100mg/ml USP Great Day/am Formula Tab Multiple Vitamins - Tablet Thiamine HCl Tab 25mg Strovite Forte Caplet FolaMed DHA Mor-vites Tab Megavite Rx Pro Hers Vanilla PNV Prenatal Plus Multivitamin M.V.I. Adult Numark Multivitamins Pnv Ob DHA Q.T. #4 Vitamin and Mineral Dietary Supplement B-complex Swiss One Timed Release Tab Prenatal Mega Antioxidant Q.T. Vitamin and Mineral Drink Mix Mega Capsules Garfield Chewable Multivitamins Tab Dalivit Fusion Plus AzesChew Insur-all Vitamin Supplement Mvc Super Multi Complete Natal DHA Livron Plus Ampoule Vitamine Du Groupe B Plus Fer - Liq Dialyvite 3000 Cedevita Sugar-free Vitamin Supplement Carbassist Tablets Multiple Vit Plus Iron Tab Vp-heme Ob Nutra Boost Children's Chewable Multi Vit W Iron TM-Vite RX Folic-K Kanga Sport Vitamins B & C Plus Minerals Stress Formula + Iron B Complex W C and B12 Inj Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Nrg Plus Liq Daily Energy Brand B-complex Vena-Bal DHA Childrens Chewable Multiple Vitamins W.iron Hylazinc Multiple Vitamins and Minerals Natural Source Spectrum With Beta Carotene Se-Natal 19 Bacmin Floradix Formula Liq Betaxin B Vitamin Compound With B12 Thunas Thrivite 19 Infuvite Adult Tricare Prenatal DHA One Rx Multivitamin Beminal W C Fortis Inj Focalgin CA Se-Plete DHA B-50 Complex Multi-12 Pediatric Multivitamins and Minerals for Men Vigem 12 Liquid NephPlex Rx Multi-Vitamin Fluoride Multi Vitamin and Fluoride MVC-Fluoride Multi-phyto Capsules RE Nata OB Replavite TriphroCaps Geritol Liquid Vitamin B1 Tablets 100mg Balanced B-50 Complex Spectrum Performa Multivitamins and Minerals Tablets Lysamine Diet Supp Amp-tab NESTABS Prenatal Multi-vitamin/Mineral Supplement Stress Tablets Kindervites Multi-force for Adults Tab Poly-VI-sol Drops Prenatal Vitamins and Minerals Tablets Magnum-75 Vitamin and Mineral Supplement Premium Prenatal Prometa Stresstabs + Zinc-copper Vitamin B1 Tab 100mg Super Vita-vim With Beta-carotene - Tab Maximum Once A Day Acti-thiamine Caplet 100mg Trinaz Super Daily No 2 Mvc 9+4 Inj Hormodausse Plus Calc Et D Tab Maintain Multiple Vitamin & Minerals Children's Chewable Vit and Min Tab Cal M Tab Multi #2 Vita Day Tab Childrens Chewable Multiple Vitamins B C Antistress Cap Beminal With C Fortis Cap Pediatric Infuvite Multiple Vitamins Vasula Tab Multivitamine Biovita Poly Vi Flor Chewable Tab HemeNatal OB plus DHA Junior Multi Vitamins - Regular Children's Chewable Multivitamins With Minerals Croq-vit Pour Enfants Reno Caps Vita Vim Multivitamins and Minerals Tab Multi Vitamin Plus Iron Sopalamine/3b Plus C Vitamin B Complex W C 300mg Tab Multiple Vitamins Childrens Chewable Super-pote Vitamin Supplement Derma-force Davimet with Fluoride Multiple Vitamins With Iron Neo Vites Tab Vitaplex Vitrexyl plus Iron VitaPhil Aide For Kids Only Chewable Multivit. Plus Iron Complexe B-75 Megavites Tab Phosthenine Vitamines Et Fer (ampoules Buvable) PreNatal Vitamins Plus Thiamine HCL 100 mg Edge OB Complete One A Day Tab Multivitamins and Minerals for Young Women Virt-Pn Vitamin B Complex MI-Vite RX Vitamin & Mineral Formula 1 Dietary Supplement FolaGent DHA Extra Once A Day Maxi 6 Liq Nutrifer Plus Tablets Super B Compound W 500mg Vit C Vitabanks Vitamin Tab Spectrum 2 Cap Foltabs Prenatal Plus DHA B Complex 25mg Vitamin Supplement Duet DHA Balanced Manganese 50mg Plus B1 & E Tab Extra P.N. Vitamin-mineral Drink Mix Multi-Vitamin With Fluoride Finazol Neo Bex Elixir Neonatal Vitamin One A Day Advance Adults NEONATAL Complete Dothelle DHA Neonatal Plus Vitamin B Complex W C Forte Cap Omnivex Revival 1 Tab WesCaps Chewable Adult Multivitamins With Minerals Stress B Complex With C and E Tab Liqui B Complex Plus Opti-manganese + B1 + C Caplet NovaMV Multivitamin Children's Chewable With Iron Twin G.F. Powder B-100 Vitamin Supplement PR Natal 400 B-complex 50 Dayavite Adult Formula 50+ Livita Children Multi Flow Tablets Multiple Vitamins and Minerals Capsules Poly-VI-flor Multivitamines Infant Multivitamin Drops Chela Potassium Plus PreGen DHA High Potency Vitamin B Complex + C Tab Multivitamin with 1.0 mg Fluoride Mycelized Childrens Multi-vitamin Liq Stress Complex 600 Avec Vit E Cuivre Zinc Folica BE Beminal Fortis Elx Multi-actin Quflora Pediatric Drops Liquid B Complex 50 PNV Prenatal Vitamin Plus Vitamin A Virt-Vite Plus Revitex Ampoules Et Comprimes Pregnancy Multivitamin Folic 5 Vitamin B Complex + C 300mg Cap Children's Chewable Multivitamins and Minerals Childrens Chewable Tab Genicin Vita-Q Omniquin Thiamiject Injection - Liq Im IV 100mg/ml vitaMedMD Rx Plus THIAMINE HCl Fortamines 10 Capsules Formula B C. Vit-min Formula For Kids Only Chewable Multivitamins Multivitamin & Minerals (iron Free) Folika-NC Hi Potency B Complex W Chelated Minerals Zavitrol Concept OB Materna - Tab Prenatabs FA Tricare Prenatal DHA One Multi Tabs Hylavite Tandem Plus Vitaphil DHA Focalgin 90 DHA Bewon Elixir Kimchi Vitamin chewable multivitamin Children's Chewable Multi Vitamins With Iron Tablets Multisol Taron-C DHA Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Mega Balance Thiamine Hydrochloride Injection, USP Virt-Caps B-plex 100 Vp-pnv-dha Zyvit Pnv-OB-dha V-Natal Poly-Vi-Flor with Iron Maltlevol 12 Liq L-Methyl PNV DHA Vitamin B Complex Plus 300mg Vitamin C Potassium Plus Vit B Complex Century Complete C.R.T. X Multivitamin & Mineral Powder Mix Chela Iron Plus C,b Complex Chewable Children's Complete Multivitamins With Essential Minerals Cyroplex Kanga-B Vitamin B Group + C Adeks Tablets Kids Stuff With Iron Tablets Se-Natal One PR Natal 430 Children's Multivitamins With Iron Stress Formula B-comp + 500mg Vit C Tab Spark Cap Maltlevol Liq Stress B Capsules With Vitamin C M.V.I. Paediatric One A Day Tab Tricare Prenatal Quick Dissolve Time Release B 100 Compound - Tablet Balanced B-100 Timed Release Puralor RE Prenatal Multivitamin with Iron TRONVite Soluvit N Paire OB Plus DHA Ultimate OB DHA Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Multivitamins W Iron Nutrilite Double X Jenliva Vitamin B Complex Suppl Chela-manganese 50 Plus Surbex-500 With Iron Foliflex Infa Drops Multivitamins Multi-force for Women Tab Dexivite Infantol Drops H.W. Children's Chewable Multi Vit & Mineral RE FAC-x B Compound 50mg Tab Se-Tan PLUS healthy mamaBE WELL ROUNDED BE WELL ROUNDED OB Complete 400 Swiss Total One Chewable Multivitamins Plus Iron Multi-Nate 30 One Daily VITES Prena1 Davimet B-plex Thiamine Hydrochloride Abavite Grand Master Formula Tab Master Key Multi Vitamin Multi Mineral Formula 2 Men's Biomultiple Vitamin and Mineral Supplement OB Complete Prenatal Childrens Chewable Vitamins W Iron Relnate DHA
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682