VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	approved nutraceutical investigational vet_approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Antiberiberi factor Aneurin thiamine(1+) thiaminium Thiamine mononitrate Thiaminum Thiamine chloride Vitamin B1 Thiamin Thiamine hydrochloride Tiamina thiamine(1+) ion Thiamine
Brand Names	Multiple Vitamins Plus Iron for Women CitraNatal 90 DHA Complexe B Compose 75 Mvc 9+4 Inj B Complex Plus C 300mg Tab Prenatrix Neo Bex Elixir Virt-Advance Multi Pro WesNate DHA NovaFerrum Multivitamin with Iron Pediatric Drops Supplement De Multivitamines Infusion Arome Fruits Rouges Beminal 500 Tab Feminique W Iron and Calcium Tab Stress B With 1000 Mg Vitamin C B-Combo Balanced B100 Bev 29 Tab Duet DHA Balanced Milltrium Senior Vitamin and Mineral Supplement Spark Cap Daily-Vite Dia-vite Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Gesticare DHA Multra With Iron Multivitamin Drops with Fluoride Stress Formula + Iron Vital Be-100 Zatean-Pn Appedrine B Vitamin Compound With B12 Thunas Childrens Chewable Tab Gestamine Comprimes Iron Folate Plus Tricare Prenatal Vitamin B1 100mg Tablet Methaver Ultimate OB DHA Multi-12/k1 Pediatric Orange Flavored Crystal Chews Tab Gemvites Jr Tab Chewable Multivit Et Fer Ampoules Et Comprimes Prena1 Vita B + C 500 Tab Chela-manganese 50 Plus WesTab Plus Nutra Boost Osteo-force Pregnancy Multivitamin Folic 5 Poly-VI-flor Multitam Children's Chew Multi & Min Tab Timed Release Vita-vim Srt B-complex Tab Vitalife - Capsule Doctor's Choice Brand for Men Vitafol Plus Vitamin B1 Tab 100mg USP Quflora Pediatric Drops Ventrixyl Fizz Multivitamins for Kids W C Loz Vitamin B Complex W C Tab Multi Tabs Duet DHA 400 Nutrol-B-complex Prenatal, DHA Thiamine Hydrochloride Injection USP, 100mg/ml Obstetrix DHA Combo Pack Mega Plex IV - Pck Allbee C 800 Tab Efferlife Multivitamins and Minerals Multi-12 Pediatric Vitamine B1 100 Mg - Tablet B-complex 50 L-Methyl PNV DHA NataFort Folet DHA MVC-Fluoride Sibergin B - Cap Tandem OB Twin Ultra Liquid Orange Flavor RE FAC-x Chewable Multivitamins Plus Iron V & M Vitamin and Mineral Supplement Vtb Vitamin and Mineral Supplement Virt-Vite Plus Viamon Ampoules Et Comprimes Opti-manganese + B1 + C Caplet Adult Infuvite Multiple Vitamins Toni Com Liq Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Stress B Capsules With Vitamin C Biovita Stress Formula Multivitamin Tablets USP Pregnancy Multivitamin Glyco-aide Tab Floriva Thiamine HCl 100mg W C 20mg Garfield Chewable Multivitamins Tab Sopalamine/3b Tab PreferaOB Multi-vitamines Enfants Comprime Vitamine Du Groupe B Plus Fer - Liq Multi-Vitamin Drops with Fluoride and Iron Essential B Tablets THIAMINE HYDROCHLORIDE injection, solution Innersource Tab Zintrexyl-C Classic Swiss One 10 Multivitamin and Mineral Tab PreferaOB plus DHA M.V.I.-12 Women's Formula Childrens Chewable Multiple Vitamins Phytoplex B Liq Taron-C DHA Vitamin B1 100 mg Obstetrix EC Multi 12 Injection Neomultivite Adeks Tablets Maltlevol Liq Enviroflex - Tab Chewable Multiple Vitamins Tab Complete Natal DHA Carbassist Tablets Complex 5 - Pwr Multivitamin & Minerals (iron Free) Multivitamin with fluoride Multi-kid Poly-Vi-Flor Bev B-150 Vitaflex Dietary Suplement Dayavite Multivitamins Biovim Tab Tini-cal Ampoules CitraNatal Rx Vitramyn B Complex With C 300mg Multi Vitamin with Fluoride Neo-bex TM-Vite RX Stress B Complex With C,e, Zinc and Copper P.N. Vitamin-mineral Drink Premium Prenatal Duet DHA Geritol Liquid Mycelized Childrens Multi-vitamin Liq Multivitamin with 1.0 mg Fluoride Twin G.F. Powder Virt Nate Multi Vitamin Drops with Fluoride and Iron Virt-Tabs Vitamin B Complex W C 300mg Tab Thiamine HCl Tab 50mg C. Vit-min Formula Croq-vit Pour Enfants Multivitamins W Iron Insur-all Vitamin Supplement Cavan Prenatal Vita Plex Tab Multi-Vitamin With Fluoride Floravit - Syr Se-Natal 19 Chewable Kanga-V Multivitamins & Minerals Rocky Mountain Multiple Vit and Min Mega Tab Thiamine HCL 100 mg DuetDHA Complete Novel Vita AzesChew Select OB Stress Vitamin B With C Complex Tablets Deriton Potassium Plus Vit B Complex B-plus - Tab Prenatvite Plus Forty Plus Vitamin Supplement Vitamin B Complex Tab Tendera-OB RenaPlex-D Vena-Bal DHA Complete-RF Prenatal Vitamin B Complex + C 300mg Cap Children Choice Multivit Chewable Tab Pnv Ob DHA VitaXyme Super Daily No 2 B Complex W Vitamin C Fortis Cap Surbex-500 With Iron Flintstones Multiple Vitamins Tab Children's Chewable Tab Vitazyme Vitamin and Mineral Supplement - Liq Ultra Enerforce Xyzbac G Dexatrim Tablets Bugs Bunny and Friends Multiple Vitamins Vol-Plus Childrens Chewable Multiple Vitamins W.iron Tricare Prenatal DHA One Chewable Multiple Vitamins for Children Vitafer - Liq One Daily VITES B Complex With C 550mg Trinaz Vol-Tab Rx Zyvit Kimchi Vitamin chewable multivitamin Q.T. Vitamin and Mineral Drink Mix Preplus Kid's Choice Children's Chewable Vitamins - Tab Neonatal Plus Vitamin Swiss One Formula Fm Vitamins & Minerals Tab Supravite Pour Enfants Fusion Plus Edge OB PROTECT IRON Liquid Jenliva Multivitamins and Minerals for Women Tender Age Multi Vitamins Maxi 6 Liq TriStart DHA Kanga-B Vitamin B Group + C Timed Release B Complex 100 Srt Livita Children Vitamin B-1 100 Mg Tablets Natalvirt 90dha MultiVitamin with Fluoride Drops Floriva Plus Vit B1 Ctr Srt 100mg Vitamin B Complex Plus C 300mg Timed Release B Complex Tablets Neo-bex Injectable Allbee With Vitamin C Cap Multivitamins W Minerals Extra Strength Children's Vitamins Chewable Balanced B50 Complex Fibrik Avon Vitadvance Multi-kids Complete O-Cal FA multivitamin Mega 13 Multivitamin Formula Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops For Kids Only Chewable Multivitamins - Tab Vitamin B1 100mg Mega-vim 75 With Beta-carotene - Tablets B-50 Hi Potency B Vitamins Tab M.V.I. Paediatric For-2 Gtf Support Caplet Thiamiject Injection - Liq Im IV 100mg/ml RE Prenatal Multivitamin with Iron Iberet 500 One A Day Advance Fem Vita-B-75 Cap Lysamine Diet Supp Amp-tab NephPlex Rx Irospan 24/6 Multi Vitamin Drops with Fluoride with Iron B-100 Caps Chewable Multiple Vitamins Plus Extra C Time Release B 100 Compound - Tablet Hi Potency B Complex W Chelated Minerals NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Trinatal GT Body Rox Phytovim Cap Pro Hers Vanilla RenaPlex TRONVite Betaxin CitraNatal Essence Mvc 9 Plus 3 Inj Vitamin B Complex Plus 300mg Vitamin C B Virol Spectrum 2 Cap Right Choice A.M. Multi Formula - Caplet Multiple Vitamins and Minerals Capsules SetonET-EC Vigem 12 Liquid Prenatal Vitamin and Mineral Supplement Somarexin and C 1000 Liqui B Complex Plus Stress B-complex Plus Iron With Vitamins C&e Kanga-kid Multi-vitamin & Mineral K.L. Vitamin-mineral Thrivite Rx MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Men's 50+ B Complex W C and B12 Inj Daily Energy Brand B-complex Timed Release B-complex 50 VitaPhil Aide Vitrexate FE CitraNatal DHA RE Nata B-complex 100 B-1 Caps 500mg Poly-Vitamin with Fluoride OB Complete DHA PR Natal 400 Cda-21 Vitamins With Non-medicinal Probiotic Complex Children's Chewable Multivitamin Complete With Minerals Multiple Vitamins W Iron Tab One A Day Advance Adults Chewable Children's Complete Multivitamins With Essential Minerals Fortistress Tab Select-OB Plus DHA Prenatal Supplement Plus DHA PNV Tabs 29-1 Stress Forte Plus Lipotropic Factors Vol-Care Rx Chromease Tab Multinate DHA Usana Megavitamin Tablets - Tab Vitafol Fe Plus Complete One-A-day - Tab B-complex Tablets Fem Time Tab Hemocyte Plus MultiVitamin with Fluoride Azesco PrePLUS Revival 1 Tab Prenatal Supplement - Tab G.A.S. Complex Hemarexin Amp PM Caps Viva Kids - Tab Hemarexin Tab MultiVitamin with Fluoride Chewable One Daily Vitamin and Mineral Dietary Supplement Multivitamine Complete Multivitamins and Minerals Tablets Timed Release Vitafol OB Caplet Premium Prenatal - Tablets Stress Complex 600 Avec Vit E Cuivre Zinc Children's Chewable Multivitamins With Minerals PreNatal Vitamins Plus Maxine Vitamin and Mineral Supplement Vitamines Et Mineraux Enfants 970 Multi-Vitamin with Fluoride Cedevita Plus Vitamin Supplement Multiple Vitamins Plus Iron - Tab Multicaps Megavite Rx Multiple Vitamins Plus Iron Tab Prenatal Mega Antioxidant Multi Vitamin, Iron and Fluoride Natural Source Spectrum With Beta Carotene PreTAB Dexifol Hi Potency Balanced B-100 Complex - Tab Davimet-M Dynam Ampoule Et Tablet Multiple Vitamins Childrens Chewable Vita-worth B-complex Tablets Children's Chewable Vit and Min Tab Formula Gm Sopalamine 3b Plus B-complex Natal-V RX Multi-vitamin/Multi-mineral Multi-phyto Capsules Livita Adults THIAMINE HCl Cavan Folate OB 50 Plus Multiple Vitamins & Minerals Multivitamins and Multiminerals Formula Regular Tablet RE Nata OB Stress Ctr Srt Marnatal F Amladex Choice OB DHA Formula B Nrg Plus Liq Ventrixyl Fe Mebolic Vc II SetonET Neonatal Vitamin Ribotin-E PR Natal 400 ec Adult Formula 50+ Vege Swiss One Multivitamin W Chel Mins Tab Hi Potency Multi Tab Magnum-75 Vitamin and Mineral Supplement Bacmin Folica-V Kanga-kid Vitamins & Iron M.V.I. 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Plus Iron Formula Lf One Tablet Daily Mens Formula Children's Chewable Multivitamin and Multimineral Cal M Tab Century Complete Children's Vitamins W Iron Chewable HemeNatal OB plus DHA NESTABS Prenatal Multi-vitamin/Mineral Supplement Revitex Ampoules Et Comprimes Children's Chewable With Iron MultiVitamin Drops with Fluoride and Iron Glyco Plus Ect Duet DHA 400 ec Lipovite Multisol One A Day Multiple Vit W Minerals Tricare Prenatal Quick Dissolve Stress B Complex With C, E and Iron Tab Vita-Rx Diabetic Vitamin Iron, Vit & Min Supp Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass High Potency Vitamin B Complex + C Tab Alkadrenergy Tablets Tonicol Et A-D-C Ampoules/comprimes Kids Stuff With Iron Tablets Vitamin B + C Cap Z Bec Tab Multiple Vitamins & Minerals Tablets Surbex-500 With Zinc Vitamines Pour Bebes Et Enfants OB Complete Prenatal Sopalamine/3b Plus C Advanced B & T Formula Mega Plex III - Pck Palm Springs Multvit and Min Tab Vitamines Et Mineraux Comprimes Infuvite Adult N.E.U. Complex Hi Potency Stress B Tension With C Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo MultiVitamin, Iron and Fluoride Drops Orti B Nutrifer Plus Tablets Fortaplex Inj Swiss One Multivitamin and Mineral Caplet Floradix Formula Liq B-100 Vitamin Supplement Multiple Vitamins With Iron Tablets Vasodyn Tab Prenatal Vitamin and Mineral Supplement -tab Chela-chromium 200 Revit Multi-vitamins and Minerals Multi II IV Vi Tab Multi-vitamins With Minerals Vitamin B1 Tab 100mg M.V.I. Adult Daily Balance Tab Super Stress Capsules Vitrexate Nutrilite Double X Multivitamins and Minerals for Men Thiamine HCl Tab 100mg Paramettes Chewable Multivits With Iron Tab Livron Plus Ampoule Vasculine Pnv-VP-U PureFe Plus Vitaday Junior Tab Corvita Venexa Multivitamines Et Mineraux Junior Regulier Se-Natal 19 Thiamine Hydrochloride Inj 100mg/ml Wellness Formula Vitamin B1 Balanced B-50 B-complex Vitamins, Timed Rele Active FE Livron Plus Tab Multi-vitamin Dietary Supplement Multi Vitamin and Fluoride Cavan Folate DHA Materna - Tab Balanced B-50 B-complex Vitamins Tab Pediatric Infuvite Multiple Vitamins Thiamine HCl Tab 25mg Flintstones Multiple Vitamins V-Natal Vita Day Tab Nutri-Tab OB plus DHA Pregvit Folic 5 Hypo Vites Tab Children Choice Multivitamin W Iron Chew Tab Lexazin Multi Enfants Tab Neo-vites & Minerals Tab Formula D.S. Senior Multi One WestGel DHA Supravite Bouteille 250ml Multi Nt-OX Men's Biomultiple Vitamin and Mineral Supplement Childrens Chewable Vitamins W Iron Hi Potency B52 B Complex Tab Prenatal Vitamins and Minerals Tablets Balanced B-100 B-complex Vitamins Tab TriphroCaps Multivitamines Plus Fer Pour Enfants (chewable Tablets) FolaMed DHA Lipotropic Ctr Thiamine Hydrochloride Multipack II C.R.T. X Multivitamin & Mineral Powder Mix Vitranol B-plex 100 PNV Prenatal Plus Multivitamin Neo Vites Tab Multi - N.T.O.x Formula - Tab Vitafol Ultra Maximum Once A Day Prenatvite Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Vitamin B Tablets Provida OB Se-Natal Super Vitalex Ampoule Buvable Vitogen B Stress C Vit E Zinc & Cop Vit-HA Multi Vitamin and Zinc Supplement Balanced B-complex Vit + Vit C&e Tab Complex-75 FloraFol Multi-force for Adults Tab Multi-vitamins OB Complete 400 Prenatal and Post Partum Supplement Maxum Multi-vite Vitachrom Gc Flintstones Multiple Vitamins Plus Iron Bewon Elixir 0.05mg/ml Kids Stuff Tablets PNV Ferrous Fumarate Docusate Folic Acid Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Permathene-12 - Caplet Multi-Vitamin Everyday Multiple Vitamins Multiple Vitamin Plus Minerals Tab Multi-Vit with Fluoride and Iron Centratex One-A-day Advance Men's Hormodausse Plus Calc Et D Tab Childrens Chewable Multiple Vitamins Plus Fe Multiple Vit Plus Iron Tab Myhephron Dialysis and Stress Supplement Vege 1 Daily Tab TriAdvance Thiamine Super Vita Vim Multivitamins and Minerals B Plus C 300mg Timed Release Vitaphil DHA Pretrate Children's Chewable Multi Vit W Iron Dialyvite 3000 Twin Ultra Liquid Lemon-lime Flavor Vit B Complex Ctr Prenate Elite Vitamin B1 Tab 2mg USP Stress Tab With Iron and Vitamin E Am Caps E.S.T. Complex Multi Flow Tablets Central-vite 18 Essential Balanced B 125 Srt Numark Multivitamins Vita Vim Multivitamins and Minerals Tab Vita-vim With Beta-carotene - Tab Swiss One Multi Vit & Chel Min Tab B Plus C 300 mg PreNatal 19 Vasula Tab Prenatal Vitamins Plus Animal Shapes Nitro Vites - Tab Diaplex Active OB Children's Chewable Multiple Vit.plus Iron Cyroplex Vita-amine Cap 100mg Formula O.C. Oncovite Davimet Orifer F Cc II Lorid Relnate DHA Formula Hh Prenatol-M Twin G.F. Powder Vanilla Flavor Vita B Complex Tab Twin Opti Pwr Vitamin B Compound Tab PNV-First B6 Plus Tab OB Complete Petite Chewable Multiple Vitamins Plus Iron Tab PureFe OB Plus Antlerviron Vital-D Rx Folika-T Children's Multivitamins Multiple Vitamins With Iron Chewable Adult Multivitamins With Minerals Multi Spectrum - Tablet VP-Vite Rx Niva-Plus Animal Shapes w/Iron Chewtabs Dexatran B-100 Hi Potency B Vitamins Tab Multiple Vitamins W Minerals Tab Stress B Complex With C and E Tab Vitamines Et Mineraux Complexe B 75mg Virt-Caps Natavite Multivitamins and Minerals for Young Women Childrens Chewable Multiple Vitamins Tab NEONATAL Complete Phytofortis + Calcium A-D Stress Tab With Zinc, Copper and Vitamin E WesCap-C-DHA Revit Tab NataChew Super Charged Energy Maltlevol 12 Liq Soluvit N Multi Vitamines - Liq Vitamin B Complex Foltabs Prenatal Plus DHA Meplex T 750 Multi-Nate 30 Multi-Vitamin Fluoride and Iron Drops Multitabs Everyday Multiple Vitamins With Iron Multivitamines Olympian Multi Vit Plus Minerals Tab Master Key Multi Vitamin Multi Mineral Formula 2 Prenatal Plus Multi 1000 Multivit-liq Balanced B-50 Complex Stresstabs + Zinc-copper Timed Release B-complex 100 ahoSAN T.R.I. B-plex Src Dalivit Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Folika-V Davimet with Fluoride P.R.O. Complex Puralor Se-Natal One B 50 Capsules Stress Tablets Thiamine HCl Inj 100mg/ml Prevital Tab Stress Tab C-B Complex Childrens Chew Multi Vitamin Tab Gynedyn Tab Multiple Vitamins With Minerals Tablets Strovite Forte Caplet Stress Formula Multi-B Comp + 500mg Vit C Cap Paramettes Chewable Multivitamins Plus Iron Multitol-M High Potency Multivitamins & Minerals Caplets Multi-11 Prenatal Vitamins Plus Low Iron Prometa Chewable Multivitamins Liquid B Complex 50 Synergistic Manganese Capsules Essential Vitamins and Minerals Isotonix Multitech Vitamin Mineral Supplemen Onccor Multiple Vitamin Tab Alertonic Prenatal Dialyvite PureVit DualFe Plus Re Ob 90 DHA Virt-PN Kenwood Liquid Supplement DaVITE Stress Formula B-comp + 500mg Vit C Tab Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Escavite Lq Trinatal Ultra Vitamin B Cpd W Vit C Tab Nutra-clear Paire OB Plus DHA Multivitamins and Minerals Tablets OBTREX DHA Combo Pack Thiamine HCl Injection - Liq 100mg/ml Vimeral Tab Low Potency B Complex Tab Ziphex Vitamin & Mineral Formula 1 Dietary Supplement vitaMedMD One Rx Prenatryl Infant Multivitamin Drops Maxi 10 Tab Renate DHA Multi Vitamin Plus Iron Multi Plex I - Tab Multiple Vitamins and Minerals Tab Somavit Brand Vitamins and Minerals Complex Women's Change Formula Gtf-vitamin-minerals & Pancreatin Tab Acti-MN + B1 + C Caplet Vitamine 110 Liq Renal Caps Dialysis/Stress Vitamin Supplement B-plex Phytopure Natalvirt Ca Revitalize Multi-vitamin and Mineral Complex Genicin Vita-Q Distilpure Msm Poly-Vi-Sol RayaVit Vita-B Mega Vitaminerals Formula F L W One-A-day Advance Fem - Tablets Chew.multiple Vits.with Extra C for Children Beminal With C Fortis Cap Hemarexin Liquid and Drinkable Ampoules Renate Virt Vite GT Vol-Nate One A Day Tab Beminal Fortis Elx Stress B & C Caplet Mega Balance Garfield Chewable Multivits Plus Iron Tab Stressmates Dialyvite 5000 Super Vita-vim With Beta-carotene - Tab Thrivite 19 Ferra Naka Plus Vitamins PNV Prenatal Vitamin Plus Vitamin A Tricare Prenatal DHA One With Folate Beminal W C Fortis Inj C-Nate DHA Multi Vite Liq Adult Virt-Pn Vitamin B Compound W Vit C 250mg Tab Multiple Vitamins Tab Swiss Total One DuetDHA Balanced Vitafant Genicin Vita-S Trinatal Rx 1 Bugs Bunny Chew Multi Vit Plus Iron M.V.I. 12 Se-Plete DHA Men's Harvest Of Values All B Complex Tab Omega-3 Rx Complete MI-Vite RX Dialyvite Supreme D Multivitamins and Minerals for Young Men Multivitamin with Fluoride Prenatal Plus Vitamins Poly-Vite Pediatric Oral Solution Childrens Multiple Vit and Min Chew Tab WesCaps Provida DHA TL-Care DHA Focalgin CA Phosthenine Vitamines Et Fer (ampoules Buvable) CitraNatal Assure Corvite PreGen DHA Quflora FE Complete Mega B Multi-Vit-Flor Paramettes Multivits Plus Iron Tab (teens) Tricare Prenatal Compleat Twin Ultra Liquid Fruit Punch Flavor Extra P.N. Vitamin-mineral Drink Mix Quflora Pediatric Flintstones W Extra C Tab Multi-force for Women Tab Multi Vitamin Drops with Fluoride Prenatal Plus Multivitamin Plus DHA MiniCaps B Complex With C 300mg Tab Liqui Vita Multi Vite Liq Junior Super Stress Mega B Plus 1000mg Vit C Tab H.W. Children's Chewable Multi Vit & Mineral Paramettes Adults Infa Drops Multivitamins Folica BE Hylavite Prim - Royal P.M.T. Ellis Tonic tensioSAN Allbee With C 550 Cap Dothelle DHA Multi Plex II - Tab B C Antistress Cap Vitamin B1 Tablets 100mg Vyo Cylate - Pwr Only One - Tablet Mor-vites Tab Vitrexyl Foliflex Totalvit Plus PR Natal 430 Multiple Vitamins - Tablet B-100 Complex Tablets Poly-Vite/Iron Oral Solution FolaGent DHA Vitamin B Complex 100 Vyqua Complete One A Day Tab Ultimate Tab Enrich Core Pack - Children Vitamin and Mineral Supplement Multi Vitamin and Mineral vitamin Childrens Chewable Multivitamins W Iron Fortamines-10 Comprimes Multivitamines Pour Enfants (chewable Tablets) Vitamine B1 Tab 100mg USP Kaydia Patch Vitamin B-Complex Men's Multi Master Formula Supravite C 1000 Glyco Lite Ect Multinate DHA Extra Xvite Synergistic Manganese Cap Multi Vitamin & Minerals Vigo Multivitamins Drops/lozenge Vitasure B Complex 50 Vitamin Cap healthy mamaBE WELL ROUNDED BE WELL ROUNDED Multra Plex 50 Plus Spectrum Performa Multivitamins and Minerals Tablets VIL-Rx Inatal Advance Formula Pro-B B-50 Complex Multi-actin M-Natal Plus Pregvit Folic 4 Se-Tan PLUS L.G.I.T. Complexe B-75 Vitafol Caplet Envirocomplex Alsimine W Vitamins A D B Totum 500 Vitamin B-1 Thiamine HCl 100mg Iron Polysaccharides Folic Acid DHA Keylosa Multi-Vitamin Fluoride Drops B Complex 500 Tab Bal-Care DHA Essential B-50 Complex Tab One A Day Advance Adults 50+ Thiamine Hydrochloride Injection, USP Vita-vim - Tab Q.T. #4 Vitamin and Mineral Dietary Supplement B Complex W C Forte Cap New Chapter's D'adamo 4 Your Type Multiple for Type O Virt-Nate DHA Poly-VI-sol Drops Prenatvite Complete Ultra Hr Virt-Nate Hylazinc bioJET Multivitamins for Children Children's Chewable Multi-vitamin Complete With Minerals B 6 Plus Penta-thion Pwr Stress B Complex With C, E & Iron Vitamin B Complex 100 Tab Vita Balance 2000 Multi Vitamins & Minerals Prefera OB plus DHA Supravite Stress Avec Vit E Et Fer Abavite Childrens Chewable Vitamin Tab Corvite Free Materna-tab Focalgin 90 DHA Bewon Elixir Children's Chewable Multiple Vitamins (chewable Tablets) Prenate Star Se-Care Conceive Childrens Chewab Vitamin W Chel Minerals Grand Master Formula Tab Original Bioscal Forte Multi-vitamin Supplement Capsules B Complex 25mg Vitamin Supplement Escavite D Sun-rype Vitaburst Mini-B Tab Venexa FE Chela Iron Plus C,b Complex Children's Chewable Multivitamins and Minerals Infuvite Pediatric Ply Vi Sol Chewable Tab Card-floe II Tab Vita Vim With Beta Carotene-caplet Hyporyl - Tab Swiss One Timed Release Tab Pregvit Revit Plus Cap Stress B&c Tab Multivitamins and Minerals With Betacarotene Tablets O-Cal Prenatal Vitamin Children's Chewable Multi-vitamin Vitamin B Complex + C 600mg Tab Escavite NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Multivitamines Et Mineraux Moms Choice Rx Swical-energy-2 Zavitrol B-complex-50 Tab Cavan Alpha Vitaplex Manganese 50mg Plus B1 & E Tab Vita-Pac Virt-C DHA Natal PNV Nephrocaps Supravite Stress Avec Vit E Omnivex Strovite One Caplets Complete Multivitamins and Minerals for Children Mega Capsules Poly Vi Flor Chewable Tab Vitabanks Vitamin Tab Multivitamin PR Natal 430 ec Stress Formula Vitrexyl plus Iron Vinacal Zoo Chews Plus Iron Total Living Concepts Formula One - Tab Vitamin B Compound W C Tab 500mg Adeks - Dps D'pantothenic Acid-B1-B2 Tab C-force Childrens Chewable Multivitamins Megavites Tab Folitin-Z Neonatal DHA Poly-Vi-Flor with Iron Nephrocaps-QT Polymine Avec Zinc Et Cuivre Great Day/am Formula Tab Vitamin B Complex 50 Leritone Junior Twin Ultra Liquid Grape Flavor B Stress C + Iron & Vite Pnv-OB-dha Prenatal Formula Tab For Kids Only Chewable Multivitamins Luna Vitamin and Mineral Bar for Women vitaMedMD Rx Plus Junior Multi Vitamins - Regular Cavan-EC SOD DHA Cedevita Sugar-free Vitamin Supplement Multiple Vitamins Super B Compound W 500mg Vit C Protect Plus SO 60 Prenatal Vi-min Triveen-Duo DHA Integra Plus Super-pote Vitamin Supplement Paramettes Syrup Folivane-Plus with Ascorbic Acid Precursors Prena1 Plus Stress Formula Tab PNV-Select Maintain Multiple Vitamin & Minerals Folic-K B50 B Complex Tab 24 Multivitamins + Minerals B-complex With Vitamin C, Biotin, Folic Acid Kanga Sport Vitamins B & C Plus Minerals Swical-energy 3e Age Kindervites Flinstones Multiple Plus Iron L.C. Supplement Pro His Mint Multi #2 Quflora FE Pediatric Drops Foltabs Prenatal Vp-heme Ob Super Multi Hill.vite Multivitamin with 0.25 mg Fluoride Childrens Chewable Vitamins TL-Folate Multivit with Fluoride Virt-Bal DHA Plus Neonatal19 Multivitamin & Multimineral Children's Chewable Multi Vitamins hormaSAN forte Replavite Finazol Mangadyn Vitogen B Stress C600 Vitranol Fe Dialyvite with Zinc Omniquin Vit B Complex Plus Vit C 550mg Dermamed Nutrition for troubled skin Tonimol Cap Liq Concept DHA Medi Msm (methyl Sulfonyl Methane) Vitamin B Complex Suppl B1 Tab 100mg Tandem Plus Dexivite Viva CT Prenatal Bal-Care DHA Thiamine Hydrochloride Inj 100mg/ml USP Multi-Vit with Fluoride Surbex 500 Filmtab HemeNatal OB Chewable Multiple Vit Plus Iron for Children Stress Formula Vit B With C Complex Chela Potassium Plus Nutra-Z One Per Day Vitamin and Mineral Dietary Supplement Mvc Materna Multiple Vitamins and Minerals Vp-pnv-dha B1 400mg Ctr Tab B Complex W Vit C W Non-med Yeast&liver Tab Multi Vitamin - Mineral Reaphirm Plant Source DHA B Compound 50mg Tab Children's Chewable Multi Vitamins With Iron Tablets Elite OB Prenatal Multivitamin B50 Complex Super Pantoplex B Complex 50+ Caplet Lipo-B-C Tab Multi-Vitamin Fluoride Vitaday Tab Vitafol One Folivane-OB PreQue 10 Davimet with Iron Xyzbac Multi Vitamin-mineral Formula Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Multi Rol Beminal With C Fortis Pws Balanced B-100 Timed Release Vitamin B Compound With Vitamin C Fortis Capsule Dtc Vinate AZ Women's Biomultiple Vitamin and Mineral Supplement Multi B Reno Caps CompleteNate Chewable Infantol Drops Nephron FA P.N.P. Vitamin Drink Prenara NeuroBion Supravite Stress Avec Vit E Cuivre Et Zinc Tricare Prenatal 2-part Daily Prenatal Vitamin System Liqui Infant Vitamins Tricare Prenatal DHA One Rx Multivitamin Betaxin Liq 100mg/ml Fortamines 10 Capsules Nutri-Tab OB NovaMV Multivitamin Multivitamins and Minerals - Complete Prenatabs FA Children's Multivitamins With Iron Vitaphil 90 DHA B With C 500 Cap WesNatal DHA Complete Folika-NC Zalvit Vp-heme Ob DHA Zoo Chews Cavan Heme OB Children's Chewable Multiple Vitamins - Tab Supravite 10ml Ampoule Prenatal Plus Iron Acti-thiamine Caplet 100mg Prenatal Vitamin and Mineral Supplement Tab Formula Gly Concept OB Extra Once A Day INATAL Ultra Zeldana TL-Fluorivite Liqui B Complex Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Nata Komplete
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682