VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

Find Related PDB Entry
22 entries where VIB is found as a standalone ligand

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	nutraceutical approved vet_approved investigational
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiaminum Thiamine Tiamina Thiamine hydrochloride Thiamine mononitrate thiaminium thiamine(1+) ion Thiamine chloride Aneurin Antiberiberi factor Vitamin B1 Thiamin thiamine(1+)
Brand Names	Numark Multivitamins Dexifol Vitamin B Complex Tab Vitafol Ultra B With C 500 Cap Everyday Multiple Vitamins With Iron PreferaOB Provida DHA FolaGent DHA Essential Vitamins and Minerals VitaXyme MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Swical-energy 3e Age Stress B Capsules With Vitamin C Active OB RayaVit Formula Pro-B Super Vita Vim Multivitamins and Minerals Vitamin B Complex W C Tab Complete-RF Prenatal Mega-vim 75 With Beta-carotene - Tablets Multiple Vitamins W Iron Tab tensioSAN Cal M Tab Neo-vites & Minerals Tab Vigem 12 Liquid Quflora Pediatric Escavite Distilpure Msm Poly-Vi-Flor with Iron Vitaphil 90 DHA 50 Plus Multiple Vitamins & Minerals Prenatvite Plus Vyo Cylate - Pwr Avon Vitadvance Multi-kids Complete Manganese 50mg Plus B1 & E Tab For-2 Virt-Bal DHA Plus vitaMedMD One Rx Wellness Formula Milltrium Senior Vitamin and Mineral Supplement Viamon Ampoules Et Comprimes Xvite Advanced B & T Formula Vitamin B1 Tab 100mg USP Vitamin B Compound W Vit C 250mg Tab Kanga-kid Vitamins & Iron ahoSAN B Complex 50+ Caplet Childrens Chewable Multiple Vitamins Hi Potency Multi Tab Kids Stuff Tablets Liqui B Complex Plus Paramettes Chewable Multivits With Iron Tab Maxine Vitamin and Mineral Supplement Keylosa Surbex 500 Filmtab NataChew Multivitamines Et Mineraux K.L. Vitamin-mineral Beminal W C Fortis Inj CitraNatal 90 DHA Multivitamines Stress Vitamin B With C Complex Tablets Swiss One Multivitamin and Mineral Caplet Vitafant Vitamines Pour Bebes Et Enfants Venexa FE Tonimol Cap Liq Balanced B-100 Timed Release Multivitamines Et Mineraux Junior Regulier Totalvit Plus CompleteNate Chewable Omniquin Dexivite Lipo-B-C Tab Mvc B Complex Plus C 300mg Tab Cavan Heme OB Lipovite Formula Lf Multiple Vit Plus Iron Tab Multiple Vitamins and Minerals Capsules One A Day Advance Fem Vitamin B Cpd W Vit C Tab Timed Release B-complex 50 Venexa Vit B Complex Ctr L-Methyl PNV DHA B-1 Caps 500mg Escavite Lq Vol-Tab Rx For Kids Only Chewable Multivit. Plus Iron Trinaz Enviroflex - Tab Stress Tab Q.T. Vitamin and Mineral Drink Mix Vitabanks Vitamin Tab Mega Capsules L.G.I.T. Maltlevol 12 Liq Balanced B50 Complex Vp-heme Ob DHA Cc II Viva CT Prenatal Adeks - Dps Croq-vit Pour Enfants Men's Multi Master Formula Synergistic Manganese Capsules Multi-Vitamin With Fluoride Tricare Prenatal Compleat Multi II IV Vi Tab Childrens Chew Multi Vitamin Tab Pnv-OB-dha Extra P.N. Vitamin-mineral Drink Mix Chewable Multivitamins Plus Iron Duet DHA Balanced Only One - Tablet Vitaflex Dietary Suplement Glyco Lite Ect Men's 50+ Neonatal Vitamin Prenatal and Post Partum Supplement Prenatal, DHA Super Stress Mega B Plus 1000mg Vit C Tab Hemarexin Tab Infantol Drops Iron Polysaccharides Folic Acid DHA Cavan-EC SOD DHA Multivitamins and Minerals for Women Select OB B-50 Hi Potency B Vitamins Tab Vita B Complex Tab Se-Natal 19 Chewable Lipotropic Ctr Premium Prenatal PureFe OB Plus Infant Multivitamin Drops Super Charged Energy WesTab Plus For Kids Only Chewable Multivitamins - Tab Ziphex Century Complete Phosthenine Vitamines Et Fer (ampoules Buvable) Prenatal Vitamin and Mineral Supplement Dynam Ampoule Et Tablet B-100 Hi Potency B Vitamins Tab Multi Vite Liq Adult Focalgin 90 DHA Relnate DHA Vasodyn Tab Folivane-Plus with Ascorbic Acid Precursors Childrens Chewable Multiple Vitamins Tab Prenatvite Complete Folica BE Chewable Children's Complete Multivitamins With Essential Minerals Alertonic Maltlevol Liq M.V.I. Adult Multi-vitamin Dietary Supplement One A Day Advance Adults 50+ Polymine Avec Zinc Et Cuivre Natavite Prenara B Complex W C Forte Cap Multi - N.T.O.x Formula - Tab New Chapter's D'adamo 4 Your Type Multiple for Type O PNV-First Thiamine Hydrochloride Gtf-vitamin-minerals & Pancreatin Tab B-50 Complex Mor-vites Tab Poly-Vitamin with Fluoride Revival 1 Tab Multiple Vitamins and Minerals Foltabs Prenatal Plus DHA Multi Plex II - Tab Glyco Plus Ect Vitalife - Capsule NESTABS Prenatal Multi-vitamin/Mineral Supplement Multivitamin with fluoride Twin Ultra Liquid Lemon-lime Flavor Complexe B 75mg Prenatol-M Kanga-B Vitamin B Group + C Poly-VI-sol Drops PureFe Plus Cavan Folate DHA Maxum Multi-vite OBTREX DHA Combo Pack One Daily Vitamin and Mineral Dietary Supplement For Kids Only Chewable Multivitamins Stress Ctr Srt Vol-Care Rx Tricare Prenatal DHA One With Folate Multiple Vitamins With Iron Tablets Chewable Multiple Vitamins Tab B-complex Extra Once A Day Multi Vitamin with Fluoride INATAL Ultra Bev B-150 Children's Multivitamins Vitranol Super B Compound W 500mg Vit C Neo-bex Tricare Prenatal DHA One Pregnancy Multivitamin Vena-Bal DHA Se-Natal 19 Twin Ultra Liquid Orange Flavor Vita-Pac Stress Formula B-comp + 500mg Vit C Tab Children's Chewable Multi Vitamins With Iron Tablets Complex-75 Vitamine Du Groupe B Plus Fer - Liq One-A-day Advance Fem - Tablets Vc II Kenwood Liquid Supplement Stress B Complex With C, E and Iron Tab Infuvite Adult Multi Vitamin and Fluoride Multitam Vita-B-75 Cap Vp-pnv-dha Multivitamine Kid's Choice Children's Chewable Vitamins - Tab Children's Chewable Multi Vit W Iron Mvc 9+4 Inj Multiple Vitamins and Minerals Tab Vitrexyl plus Iron NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Multi-Vit with Fluoride Multi-vitamins With Minerals Myhephron Dialysis and Stress Supplement PreNatal Vitamins Plus Maintain Multiple Vitamin & Minerals Strovite One Caplets Vita-vim - Tab Vol-Plus Multi Vitamin Drops with Fluoride Somavit Brand Vitamins and Minerals Complex Trinatal GT Orti B PNV-Select Tricare Prenatal Quick Dissolve Liquid B Complex 50 Super Daily No 2 D'pantothenic Acid-B1-B2 Tab Kanga-kid Multi-vitamin & Mineral Children's Vitamins Chewable Bev 29 Tab Biovim Tab Dalivit Dia-vite Preplus B50 Complex Puralor Multi-kid PNV Prenatal Plus Multivitamin Flintstones Multiple Vitamins Plus Iron Vitamin B Complex + C 600mg Tab Children's Chewable Multivitamin Complete With Minerals Multivitamins W Minerals Extra Strength Multi Vitamin - Mineral Multiple Vitamins & Minerals Tablets OB Complete DHA Virt Vite GT Betaxin Liq 100mg/ml Balanced B-50 Complex B Compound 50mg Tab RenaPlex Tandem OB Vitamin B1 Tablets 100mg Cedevita Plus Vitamin Supplement Prenatvite Palm Springs Multvit and Min Tab Complexe B-75 Corvite Mega Plex IV - Pck Paramettes Adults Sopalamine 3b Plus Thiamine Hydrochloride Injection, USP Prenatal Plus Iron Kaydia Patch Bewon Elixir Osteo-force 50 Plus PR Natal 430 ec Prenate Elite Stress Tab With Iron and Vitamin E Multi B Stress Formula Tab B Plus C 300mg Timed Release CitraNatal Rx Bacmin Nutrifer Plus Tablets TL-Fluorivite AzesChew High Potency Multivitamins & Minerals Caplets Prenatryl TriAdvance Thiamine HCl Tab 50mg B50 B Complex Tab Chela-manganese 50 Plus Innersource Tab RE Nata OB B Vitamin Compound With B12 Thunas High Potency Vitamin B Complex + C Tab Multi Plex I - Tab Nutra-Z B-plex G.A.S. Complex B-complex Tablets Replavite DaVITE Children's Chewable Multiple Vit.plus Iron Formula Gm Cavan Prenatal Ply Vi Sol Chewable Tab Multi-actin OB Complete 400 Zalvit Se-Plete DHA Chewable Multivitamins Virt-Tabs Vita Day Tab Women's Formula Daily-Vite One A Day Multiple Vit W Minerals Multi Vitamin, Iron and Fluoride PR Natal 400 Balanced B100 Chew.multiple Vits.with Extra C for Children MultiVitamin with Fluoride Renate DHA Childrens Chewable Multiple Vitamins W.iron Vitafol OB Caplet NephPlex Rx E.S.T. Complex Natal PNV Vitamin B Tablets Multivitamins and Minerals - Complete Stress Formula Multi-B Comp + 500mg Vit C Cap Hypo Vites Tab Se-Natal One Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Prenatal Supplement - Tab FloraFol Multi-Vit-Flor Mycelized Childrens Multi-vitamin Liq Orange Flavored Crystal Chews Tab Quflora FE Pediatric Drops Livron Plus Tab Vasculine THIAMINE HYDROCHLORIDE injection, solution Livita Adults Multivitamins and Minerals Tablets PreNatal 19 Ultra Hr Vitamin B1 Tab 2mg USP Prenatabs FA O-Cal Prenatal Vitamin Premium Prenatal - Tablets Children's Chewable Tab Dexatrim Tablets Z Bec Tab Women's Change Formula Vita-amine Cap 100mg Zeldana Bal-Care DHA Essential THIAMINE HCl Prenatal Vitamin and Mineral Supplement -tab Cyroplex Tender Age Multi Vitamins Ellis Tonic MI-Vite RX Glyco-aide Tab NovaMV Multivitamin Irospan 24/6 Multiple Vitamins Plus Iron - Tab One Per Day Vitamin and Mineral Dietary Supplement Vimeral Tab Vitamine B1 100 Mg - Tablet WesNate DHA Am Caps Vitamin B Complex 100 Prometa Gynedyn Tab TL-Care DHA Antlerviron Balanced B-50 B-complex Vitamins Tab Vita Vim With Beta Carotene-caplet Potassium Plus Vit B Complex Vitamine B1 Tab 100mg USP Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Mebolic Multisol Tandem Plus Soluvit N Dialyvite Fortistress Tab Vitamin B Complex 50 Vitogen B Stress C Vit E Zinc & Cop Hylazinc Multivitamines Pour Enfants (chewable Tablets) Tricare Prenatal DHA One Rx Multivitamin Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Stress B With 1000 Mg Vitamin C Multiple Vitamins Tab PR Natal 430 Megavite Rx Multinate DHA Revitex Ampoules Et Comprimes Davimet Childrens Chewab Vitamin W Chel Minerals Folitin-Z Paire OB Plus DHA Vitamin B-1 100 Mg Tablets Isotonix Multitech Vitamin Mineral Supplemen Stress Tab With Zinc, Copper and Vitamin E Iberet 500 Multiple Vitamins Timed Release Vita-vim Srt Hi Potency B Complex W Chelated Minerals Hylavite Surbex-500 With Zinc Balanced B-50 B-complex Vitamins, Timed Rele Corvite Free Multitol-M Duet DHA Neo Vites Tab Opti-manganese + B1 + C Caplet Trinatal Ultra Betaxin B-100 Complex Tablets Kids Stuff With Iron Tablets Dialyvite 5000 Foltabs Prenatal Davimet with Iron B Virol Swiss One Chewable Adult Multivitamins With Minerals Stresstabs + Zinc-copper Allbee C 800 Tab Beminal With C Fortis Pws Livron Plus Ampoule Multi-force for Adults Tab Multivitamin with Fluoride Multi Flow Tablets Vitamin B1 Folika-NC Jenliva Active FE Gtf Support Caplet Prenatal Plus Vitamins Supravite C 1000 Total Living Concepts Formula One - Tab Twin G.F. Powder Swiss Total One Vasula Tab Central-vite 18 Essential V & M Vitamin and Mineral Supplement Amladex Twin Ultra Liquid Grape Flavor Prenate Star Natal-V RX Multi-vitamin/Multi-mineral Twin G.F. Powder Vanilla Flavor Ventrixyl Fe CitraNatal Essence Multipack II Poly Vi Flor Chewable Tab Virt-Caps Gesticare DHA Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Chewable Multiple Vitamins Plus Iron Tab Vitamine 110 Liq Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass PreferaOB plus DHA Thiamine HCl Inj 100mg/ml Omnivex Ribotin-E Vitrexyl Childrens Chewable Multiple Vitamins Plus Fe Garfield Chewable Multivitamins Tab Methaver PNV Tabs 29-1 RenaPlex-D Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Integra Plus P.N. Vitamin-mineral Drink Prenatal Plus Multivitamin Plus DHA MiniCaps B Stress C + Iron & Vite Multi Vitamines - Liq Supplement De Multivitamines Infusion Arome Fruits Rouges Focalgin CA Hemarexin Liquid and Drinkable Ampoules B Complex 500 Tab DuetDHA Complete One-A-day Advance Men's Phytopure Virt-PN Complete One-A-day - Tab Junior Multi Vitamins - Regular Liqui Infant Vitamins Multi Nt-OX Vitaplex M.V.I. 12 Vol-Nate Nutri-Tab OB plus DHA Flinstones Multiple Plus Iron Vital-D Rx Pregvit Folic 4 Stress Formula Multivitamin Tablets USP Hi Potency B52 B Complex Tab Hemarexin Amp Taron-C DHA Folet DHA Acti-thiamine Caplet 100mg MultiVitamin, Iron and Fluoride Drops Spectrum Performa Multivitamins and Minerals Tablets Vitamin B Complex Plus C 300mg Timed Release Geritol Liquid B Complex 50 Vitamin Cap Multi Vitamin Drops with Fluoride with Iron B-50 Complex Tab B Plus C 300 mg Multi #2 Multi Pro Stress Formula Twin Opti Pwr Finazol Adult Formula 50+ Multi-Nate 30 Orifer F Vitamin & Mineral Formula 1 Dietary Supplement 24 Multivitamins + Minerals B Complex 25mg Vitamin Supplement Diaplex Virt-Nate DHA MultiVitamin with Fluoride Chewable Olympian Multi Vit Plus Minerals Tab Leritone Junior Multi-vitamines Enfants Comprime Liqui Vita Permathene-12 - Caplet Zyvit Children's Chewable Vit and Min Tab Vitazyme B-complex Tab Biovita Vit-HA Multi Vitamin and Zinc Supplement Dermamed Nutrition for troubled skin Fizz Multivitamins for Kids W C Loz Beminal With C Fortis Cap N.E.U. Complex OB Complete Petite Multivitamines Plus Fer Pour Enfants (chewable Tablets) One Tablet Daily Mens Formula PreGen DHA Kimchi Vitamin chewable multivitamin Spectrum 2 Cap Maxi 6 Liq Virt-Advance Megavites Tab Hi Potency Stress B Tension With C B-100 Vitamin Supplement PureVit DualFe Plus Multi-phyto Capsules Multiple Vitamins Plus Iron for Women Kanga-V Multivitamins & Minerals Stressmates PNV Ferrous Fumarate Docusate Folic Acid Time Release B 100 Compound - Tablet Animal Shapes Children's Multivitamins With Iron Tricare Prenatal 2-part Daily Prenatal Vitamin System Children's Chewable Multi-vitamin Complete With Minerals Thiamine HCl Tab 100mg Se-Care Conceive Sopalamine/3b Plus C Everyday Multiple Vitamins Children Choice Multivit Chewable Tab Mini-B Tab Sibergin B - Cap Vit B1 Ctr Srt 100mg Vitamin B Complex Plus 300mg Vitamin C Children's Chewable Multi-vitamin T.R.I. B-plex Src Senior Multi One Strovite Forte Caplet Children's Chew Multi & Min Tab Tendera-OB Renate Multi-11 VIL-Rx VitaPhil Aide Spark Cap Multi-Vitamin Drops with Fluoride and Iron Nutrol-B-complex Chewable Multiple Vitamins Plus Extra C Paramettes Chewable Multivitamins Plus Iron Multiple Vitamins - Tablet Neomultivite Poly-VI-flor MultiVitamin Drops with Fluoride and Iron Childrens Chewable Vitamins W Iron Se-Natal B-Combo Stress B & C Caplet Derma-force Kindervites Mega 13 Multivitamin Formula PNV Prenatal Vitamin Prenatal Formula Tab Xyzbac G Multi-Vitamin with Fluoride Hormodausse Plus Calc Et D Tab RE Nata Novel Vita Vita-Rx Diabetic Vitamin Childrens Chewable Tab B Complex W C and B12 Inj Super Pantoplex Luna Vitamin and Mineral Bar for Women Neo-bex Injectable Zintrexyl-C Children's Chewable Multi Vitamins Multiple Vitamins With Minerals Tablets B 50 Capsules Xyzbac Multivitamin with 0.25 mg Fluoride Thrivite 19 B-complex 50 Great Day/am Formula Tab Dialyvite with Zinc Infuvite Pediatric Obstetrix EC Zavitrol Multinate DHA Extra Formula Fm Vitamins & Minerals Tab Stress B Complex With C,e, Zinc and Copper Card-floe II Tab Vinate AZ Children's Chewable Multivitamins With Minerals Materna - Tab Balanced B-100 B-complex Vitamins Tab Multivitamins and Minerals for Young Men NovaFerrum Multivitamin with Iron Pediatric Drops Viva Kids - Tab Vitamines Et Mineraux Enfants 970 Alkadrenergy Tablets C.R.T. X Multivitamin & Mineral Powder Mix Concept OB Reaphirm Plant Source DHA Nephrocaps HemeNatal OB Twin Ultra Liquid Fruit Punch Flavor Pro His Mint Renal Caps Dialysis/Stress Vitamin Supplement Super-pote Vitamin Supplement Nephron FA Beminal 500 Tab Stress B Complex With C and E Tab Davimet with Fluoride Infa Drops Multivitamins L.C. Supplement Prenatal Plus Neonatal19 Doctor's Choice Brand for Men Childrens Multiple Vit and Min Chew Tab V-Natal Multi Vitamin Plus Iron Pregvit Folic 5 Children's Chewable Multiple Vitamins (chewable Tablets) Children's Chewable Multivitamins and Minerals Formula F L W Grand Master Formula Tab Mega Balance Super Stress Capsules Thiamine HCl Tab 25mg TL-Folate Multitabs Multi Vitamin Drops with Fluoride and Iron Vitaphil DHA PreQue 10 Stress B Complex With C, E & Iron Multivitamin & Minerals (iron Free) Multi Rol Poly-Vite/Iron Oral Solution Rocky Mountain Multiple Vit and Min Mega Tab Chela-chromium 200 Elite OB Prenatal Multivitamin Multi-Vitamin Fluoride Swiss One Multi Vit & Chel Min Tab Vitafer - Liq Vitamines Et Mineraux Comprimes Poly-Vi-Flor Thiamine HCl Injection - Liq 100mg/ml Multicaps Concept DHA Multi Vitamin & Minerals Thiamine Hydrochloride Inj 100mg/ml Multi-12 Pediatric Vitamin B Complex W C 300mg Tab Feminique W Iron and Calcium Tab Multi-Vitamin Foliflex HemeNatal OB plus DHA Natural Source Spectrum With Beta Carotene Multi Vitamin-mineral Formula Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Childrens Chewable Multivitamins W Iron Vitaday Tab Cavan Folate OB Oncovite Adult Infuvite Multiple Vitamins Formula B Materna TM-Vite RX Adeks Tablets Nata Komplete Quflora FE SetonET Revit Plus Cap Fibrik Multi Enfants Tab Vita Plex Tab Vitamin B Complex + C 300mg Cap PreTAB Phytoplex B Liq Multiple Vitamins With Iron Neo Bex Elixir Vitranol Fe Poly-Vi-Sol Vitasure Stress Formula + Iron PrePLUS Thiamine Hydrochloride Injection USP, 100mg/ml Prenatal Vitamins and Minerals Tablets Inatal Advance H.W. Children's Chewable Multi Vit & Mineral Bal-Care DHA TRONVite Pro Hers Vanilla Vege 1 Daily Tab Prenatrix Timed Release B-complex 100 Vp-heme Ob Folivane-OB Genicin Vita-S Davimet-M Supravite Stress Avec Vit E Cuivre Et Zinc Original Bioscal Forte Multi-vitamin Supplement Capsules B Complex Tablets Vitamin B Complex Suppl Prena1 Formula Hh Childrens Chewable Vitamins Floradix Formula Liq Prenatal Mega Antioxidant Hi Potency Balanced B-100 Complex - Tab Se-Tan PLUS Multivitamins and Multiminerals Formula Regular Tablet Chewable Multiple Vit Plus Iron for Children Vitachrom Gc vitaMedMD Rx Plus Fortamines-10 Comprimes Nrg Plus Liq DuetDHA Balanced Revitalize Multi-vitamin and Mineral Complex RE FAC-x Formula Gly P.R.O. Complex Vita-B Vitamin B Compound W C Tab 500mg Trinatal Rx 1 Pregvit Stress Complex 600 Avec Vit E Cuivre Zinc Chela Potassium Plus Stress B&c Tab SetonET-EC Pnv Ob DHA Vitramyn Animal Shapes w/Iron Chewtabs Livita Children Beminal Fortis Elx M.V.I. Paediatric Prenatal Vitamins Plus Virt Nate Vita Balance 2000 VP-Vite Rx Multivitamins and Minerals With Betacarotene Tablets bioJET Multi Spectrum - Tablet Thiamine HCl 100mg W C 20mg Folika-V Multivitamin & Multimineral Prenatal Vitamin and Mineral Supplement Tab Select-OB Plus DHA Prenatal Supplement Plus DHA Revit Tab Men's Biomultiple Vitamin and Mineral Supplement Centratex Complete Mega B Sun-rype Vitaburst B C Antistress Cap Vitamin B-Complex Nitro Vites - Tab Supravite 10ml Ampoule PNV Prenatal Vitamin Plus Vitamin A Bewon Elixir 0.05mg/ml Daily Energy Brand B-complex Lorid Folic-K Moms Choice Rx WesCap-C-DHA Multiple Vitamins Plus Iron Tab Nutra-clear Fusion Plus Thiamine Hydrochloride Inj 100mg/ml USP Maximum Once A Day Nutrilite Double X Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Timed Release B Complex 100 Srt Ultimate Tab Vital Be-100 Tini-cal Ampoules WesNatal DHA Complete Hyporyl - Tab Nutri-Tab OB Vitamin B1 100 mg Children's Chewable With Iron Classic Swiss One 10 Multivitamin and Mineral Tab M.V.I.-12 Omega-3 Rx Complete B Complex With C 300mg Children Choice Multivitamin W Iron Chew Tab Poly-Vite Pediatric Oral Solution Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA healthy mamaBE WELL ROUNDED BE WELL ROUNDED Folika-T Supravite Stress Avec Vit E Multi-force for Women Tab Nutra Boost Surbex-500 With Iron Floravit - Syr Iron, Vit & Min Supp Ultra Enerforce B6 Plus Tab Vitrexate B-100 Caps Gemvites Jr Tab Chewable MultiVitamin with Fluoride Drops Children's Chewable Multiple Vitamins - Tab Multivit Et Fer Ampoules Et Comprimes Multi-vitamins Allbee With Vitamin C Cap Complete Natal DHA Body Rox Multiple Vitamin Tab Multi-Vit with Fluoride and Iron Re Ob 90 DHA Ultimate OB DHA Efferlife Multivitamins and Minerals Carbassist Tablets Insur-all Vitamin Supplement NEONATAL Complete Fem Time Tab Pretrate RE Prenatal Multivitamin with Iron NataFort Appedrine Thiamine Cedevita Sugar-free Vitamin Supplement Marnatal F PROTECT IRON Liquid Super Multi Vita-vim With Beta-carotene - Tab Flintstones Multiple Vitamins Multiple Vitamin Plus Minerals Tab Multivitamins and Minerals for Men Forty Plus Vitamin Supplement Phytofortis + Calcium A-D Toni Com Liq Acti-MN + B1 + C Caplet Multivitamins and Minerals for Young Women Usana Megavitamin Tablets - Tab Vitaday Junior Tab Prenatal Vi-min Alsimine W Vitamins A D PM Caps Vitafol Plus Cda-21 Vitamins With Non-medicinal Probiotic Complex Vitamin B1 100mg Tablet Children's Chewable Multivitamin and Multimineral Corvita Stress Tablets Pediatric Infuvite Multiple Vitamins Multivitamin Vitrexate FE Harvest Of Values All B Complex Tab P.N.P. Vitamin Drink Abavite Zoo Chews Plus Iron Iron Folate Plus WestGel DHA Multiple Vitamins Childrens Chewable C. Vit-min Formula Daily Balance Tab Paramettes Syrup TriStart DHA Vitafol Fe Plus Vitamin B1 Tab 100mg Vitamines Et Mineraux Maxi 10 Tab Nephrocaps-QT Vit B Complex Plus Vit C 550mg Thrivite Rx Multi Tabs Deriton Escavite D Dialyvite Supreme D Floriva Fortamines 10 Capsules B-plus - Tab Synergistic Manganese Cap Vitamin B + C Cap Folica-V B-complex-50 Tab Paramettes Multivits Plus Iron Tab (teens) Balanced B-complex Vit + Vit C&e Tab Kanga Sport Vitamins B & C Plus Minerals Ventrixyl Multivit with Fluoride Tricare Prenatal Chela Iron Plus C,b Complex CitraNatal DHA Multi 1000 Mvc 9 Plus 3 Inj Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Gestamine Comprimes OB Complete Prenatal CitraNatal Assure Q.T. #4 Vitamin and Mineral Dietary Supplement Lysamine Diet Supp Amp-tab Vitamin and Mineral Supplement - Liq Virt-Nate MVC-Fluoride Flintstones Multiple Vitamins Tab Duet DHA 400 ec Protect Plus SO 60 NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Dialyvite 3000 Hemocyte Plus Vitamin B Compound With Vitamin C Fortis Capsule Dtc Vyqua One Daily VITES Prena1 Plus Multiple Vitamins W Minerals Tab C-B Complex Master Key Multi Vitamin Multi Mineral Formula 2 B Complex With C 300mg Tab B Complex W Vit C W Non-med Yeast&liver Tab Multi-Vitamin Fluoride Drops Multra Plex Right Choice A.M. Multi Formula - Caplet Allbee With C 550 Cap Neonatal Plus Vitamin Super Vita-vim With Beta-carotene - Tab Mangadyn Vitamin B Complex Vinacal Chromease Tab Sopalamine/3b Tab Vitamin B Compound Tab Virt-Pn Vitogen B Stress C600 Prim - Royal P.M.T. Prefera OB plus DHA Medi Msm (methyl Sulfonyl Methane) Liqui B Complex Vitamin B1 100mg M-Natal Plus B1 400mg Ctr Tab Enrich Core Pack - Children Vitamin and Mineral Supplement Quflora Pediatric Drops Super Vitalex Ampoule Buvable Virt-C DHA C-force Complexe B Compose 75 Vitafol One Zoo Chews Vita-worth B-complex Tablets Multivitamin with 1.0 mg Fluoride O-Cal FA multivitamin Triveen-Duo DHA Edge OB Supravite Pour Enfants Stress Forte Plus Lipotropic Factors Pnv-VP-U Cavan Alpha B-complex With Vitamin C, Biotin, Folic Acid Complete Multivitamins and Minerals Tablets Timed Release hormaSAN forte Azesco Bugs Bunny Chew Multi Vit Plus Iron Childrens Chewable Multivitamins Materna-tab Floriva Plus Multi Vitamins & Minerals Vege Swiss One Multivitamin W Chel Mins Tab Mega Plex III - Pck Penta-thion Pwr Choice OB DHA One A Day Advance Adults Complete Multivitamins and Minerals for Children Vitamin B Complex 100 Tab Ferra Naka Plus Vitamins B Totum 500 Reno Caps B 6 Plus Multivitamin Drops with Fluoride Neonatal DHA FolaMed DHA B1 Tab 100mg Balanced B 125 Srt Multi-Vitamin Fluoride and Iron Drops Stress Formula Vit B With C Complex Formula D.S. Vitamin B-1 Thiamine HCl 100mg M.V.I. Pediatric Provida OB Children's Vitamins W Iron Chewable Men's Multivitamins for Children Complex 5 - Pwr Multivitamins W Iron Garfield Chewable Multivits Plus Iron Tab Low Potency B Complex Tab Thiamiject Injection - Liq Im IV 100mg/ml Lexazin Stress B-complex Plus Iron With Vitamins C&e Tonicol Et A-D-C Ampoules/comprimes Essential B Tablets Vita B + C 500 Tab Envirocomplex Revit Multi-vitamins and Minerals Niva-Plus Bugs Bunny and Friends Multiple Vitamins Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Obstetrix DHA Combo Pack Complete One A Day Tab PR Natal 400 ec Genicin Vita-Q Zatean-Pn Flintstones W Extra C Tab Multi Vitamin and Mineral vitamin C-Nate DHA TriphroCaps Mega Vitaminerals B Complex W Vitamin C Fortis Cap Vita Vim Multivitamins and Minerals Tab Supravite Bouteille 250ml Magnum-75 Vitamin and Mineral Supplement Thiamine HCL 100 mg B-complex 100 Dexatran Natalvirt 90dha Childrens Chewable Vitamin Tab Meplex T 750 Fortaplex Inj Natalvirt Ca Duet DHA 400 Onccor Formula O.C. Vtb Vitamin and Mineral Supplement NeuroBion Phytovim Cap B Complex With C 550mg Multra With Iron Prenatal Vigo Multivitamins Drops/lozenge One A Day Tab Women's Biomultiple Vitamin and Mineral Supplement Chewable Multiple Vitamins for Children Multivit-liq Multivitamins Vitafol Caplet Dayavite WesCaps Multi Vite Liq Junior Multi-12/k1 Pediatric Supravite Stress Avec Vit E Et Fer B-plex 100 Multi 12 Injection Prenatal Vitamins Plus Low Iron Swiss One Timed Release Tab Pregnancy Multivitamin Folic 5 Prevital Tab Swical-energy-2 Somarexin and C 1000 Dothelle DHA Hill.vite Virt-Vite Plus
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682