VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	investigational nutraceutical vet_approved approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiamine chloride Vitamin B1 thiaminium Thiaminum Thiamine mononitrate Tiamina thiamine(1+) Thiamine Thiamin Thiamine hydrochloride Antiberiberi factor thiamine(1+) ion Aneurin
Brand Names	PreGen DHA Phytofortis + Calcium A-D Bugs Bunny Chew Multi Vit Plus Iron Children's Chewable Multivitamins With Minerals Vimeral Tab Balanced B-50 Complex Supravite Stress Avec Vit E Cuivre Et Zinc Ultimate OB DHA Vitamine 110 Liq Vitamin B Complex Tab Se-Tan PLUS Kanga Sport Vitamins B & C Plus Minerals Sibergin B - Cap Milltrium Senior Vitamin and Mineral Supplement Neo Bex Elixir Stress Formula B-comp + 500mg Vit C Tab Children's Vitamins Chewable Complex-75 hormaSAN forte One-A-day Advance Men's Mvc 9 Plus 3 Inj Davimet with Fluoride Lipotropic Ctr Nutrol-B-complex Prenatal Vitamin and Mineral Supplement Tab Venexa FE Vitamin B Cpd W Vit C Tab Vitamin B Complex Suppl Zalvit Children's Chewable Multi Vitamins Choice OB DHA Revitex Ampoules Et Comprimes Swiss One Timed Release Tab Children's Multivitamins With Iron Materna-tab Complex 5 - Pwr Bacmin B-100 Hi Potency B Vitamins Tab Maxine Vitamin and Mineral Supplement Multiple Vitamins Childrens Chewable Pregnancy Multivitamin Folic 5 Prenatvite VIL-Rx Isotonix Multitech Vitamin Mineral Supplemen Vitamin B Compound W Vit C 250mg Tab Enviroflex - Tab vitaMedMD One Rx Vitamin B1 100mg Centratex For Kids Only Chewable Multivitamins - Tab Concept DHA Duet DHA 400 Master Key Multi Vitamin Multi Mineral Formula 2 Everyday Multiple Vitamins B Complex W C Forte Cap DuetDHA Balanced Duet DHA Balanced Grand Master Formula Tab Multiple Vitamins and Minerals New Chapter's D'adamo 4 Your Type Multiple for Type O Prenatal Vitamins Plus Essential Vitamins and Minerals Multi Plex II - Tab Sopalamine/3b Plus C Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Swical-energy-2 Cavan Alpha Infuvite Pediatric Twin Ultra Liquid Lemon-lime Flavor Vtb Vitamin and Mineral Supplement Poly-Vite/Iron Oral Solution Gtf Support Caplet Daily-Vite Q.T. Vitamin and Mineral Drink Mix Multi Tabs Kanga-V Multivitamins & Minerals Medi Msm (methyl Sulfonyl Methane) FloraFol DuetDHA Complete Finazol Multivitamins and Minerals With Betacarotene Tablets Hemarexin Amp B-complex Fusion Plus Multi-Nate 30 Azesco Foltabs Prenatal Nutri-Tab OB plus DHA Gynedyn Tab NovaFerrum Multivitamin with Iron Pediatric Drops One-A-day Advance Fem - Tablets AzesChew Multi-actin Insur-all Vitamin Supplement Vitamin B Complex 100 Tandem OB Vit-HA Multi Vitamin and Zinc Supplement Multi-Vitamin Fluoride Drops Virt-Tabs Paramettes Chewable Multivitamins Plus Iron Mangadyn B Complex With C 300mg Tab Multivit Et Fer Ampoules Et Comprimes P.N. Vitamin-mineral Drink Stress Tab With Iron and Vitamin E Cal M Tab Ventrixyl Fe Z Bec Tab PNV Tabs 29-1 Keylosa NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Kanga-B Vitamin B Group + C Virt-Nate DHA Infuvite Adult Vitamine B1 100 Mg - Tablet Oncovite Zyvit Mega Plex IV - Pck Men's 50+ Complete Multivitamins and Minerals Tablets Timed Release Hyporyl - Tab Beminal W C Fortis Inj Multi-11 Multicaps Stress Formula Tab Irospan 24/6 Children's Chewable Multiple Vit.plus Iron Stress Formula + Iron Usana Megavitamin Tablets - Tab Vitamin B Tablets Extra P.N. Vitamin-mineral Drink Mix B Compound 50mg Tab Foltabs Prenatal Plus DHA Alsimine W Vitamins A D Prenatabs FA Vitranol Thiamiject Injection - Liq Im IV 100mg/ml Betaxin PNV Prenatal Vitamin Plus Vitamin A Thiamine Hydrochloride Injection, USP Vita Plex Tab Vitamin B-1 100 Mg Tablets Zoo Chews Plus Iron M.V.I. Pediatric Natavite Balanced B50 Complex PreQue 10 Swiss Total One Pregvit Folic 4 Multivitamins and Minerals for Women Stress Tab VitaXyme Vitaplex Multisol Vitamin B Complex 50 Supplement De Multivitamines Infusion Arome Fruits Rouges Vitamin and Mineral Supplement - Liq Cda-21 Vitamins With Non-medicinal Probiotic Complex INATAL Ultra Stress Formula Multi-B Comp + 500mg Vit C Cap Super Vitalex Ampoule Buvable Body Rox Kaydia Patch Active FE Viva CT Prenatal MultiVitamin with Fluoride Drops RayaVit Maltlevol 12 Liq E.S.T. Complex Prenara Vitamin B Compound Tab Balanced B100 Livita Children Natalvirt Ca Dexatrim Tablets Deriton Multi-12 Pediatric Vitazyme Nrg Plus Liq PreferaOB Complete One A Day Tab Multiple Vitamins W Minerals Tab Thiamine Hydrochloride Injection USP, 100mg/ml Replavite For Kids Only Chewable Multivitamins Time Release B 100 Compound - Tablet Zeldana Chewable Multivitamins Plus Iron Mvc 9+4 Inj Ultimate Tab Vitafol Ultra Vitamin B Complex + C 600mg Tab M.V.I. Adult Multiple Vitamins With Iron Tablets Surbex-500 With Iron Quflora FE Pediatric Drops Multiple Vitamins W Iron Tab Super B Compound W 500mg Vit C Multivitamin Materna - Tab Quflora Pediatric Childrens Chewable Vitamins W Iron Vita-amine Cap 100mg Se-Natal 19 Multi-Vitamin With Fluoride Multiple Vitamins Plus Iron for Women Gesticare DHA Ribotin-E Zatean-Pn Omniquin B50 B Complex Tab Tricare Prenatal DHA One Multiple Vitamins and Minerals Tab Multi-Vit with Fluoride and Iron Protect Plus SO 60 Vita Day Tab Dialyvite 3000 Spectrum Performa Multivitamins and Minerals Tablets Allbee C 800 Tab B 50 Capsules Vitamin B1 Tab 100mg USP OB Complete 400 Formula Hh Formula Pro-B Innersource Tab Right Choice A.M. Multi Formula - Caplet Multi Spectrum - Tablet B50 Complex ahoSAN Paramettes Syrup Chela-manganese 50 Plus Fem Time Tab Revitalize Multi-vitamin and Mineral Complex Se-Natal 19 Chewable TriStart DHA Palm Springs Multvit and Min Tab B Complex Plus C 300mg Tab H.W. Children's Chewable Multi Vit & Mineral Children's Vitamins W Iron Chewable PureFe Plus N.E.U. Complex Hill.vite Twin G.F. Powder Vanilla Flavor PR Natal 400 ec Stress B & C Caplet Xyzbac G Multi 1000 Stress B-complex Plus Iron With Vitamins C&e Tricare Prenatal DHA One Rx Multivitamin Children's Chew Multi & Min Tab Vp-heme Ob Animal Shapes Multivitamin & Minerals (iron Free) Zavitrol Natural Source Spectrum With Beta Carotene Efferlife Multivitamins and Minerals Thrivite 19 Avon Vitadvance Multi-kids Complete Childrens Multiple Vit and Min Chew Tab Card-floe II Tab Kids Stuff With Iron Tablets Swiss One Multi Vit & Chel Min Tab Multivitamins for Children Sopalamine/3b Tab Tender Age Multi Vitamins Iron Polysaccharides Folic Acid DHA Children's Multivitamins Beminal With C Fortis Cap Dialyvite Multi Nt-OX Chela-chromium 200 Childrens Chewab Vitamin W Chel Minerals Natal-V RX Multi-vitamin/Multi-mineral One A Day Advance Adults 50+ Prenatal, DHA Vigem 12 Liquid Numark Multivitamins Stress B With 1000 Mg Vitamin C SetonET-EC PreNatal Vitamins Plus Thiamine HCl Tab 100mg B-100 Vitamin Supplement Multivitamines Pour Enfants (chewable Tablets) Hi Potency Multi Tab Surbex 500 Filmtab Vita-Pac Biovita Multi-Vitamin Multiple Vitamins With Minerals Tablets bioJET Orifer F Myhephron Dialysis and Stress Supplement Tricare Prenatal DHA One With Folate Dia-vite Acti-thiamine Caplet 100mg Vitaday Junior Tab One A Day Tab Super Multi Corvite Free Multivitamines Et Mineraux Moms Choice Rx THIAMINE HCl Vita-B B Complex Tablets Mega Plex III - Pck Vege 1 Daily Tab B Vitamin Compound With B12 Thunas Childrens Chewable Multiple Vitamins W.iron Multi-force for Adults Tab Multivitamins and Multiminerals Formula Regular Tablet D'pantothenic Acid-B1-B2 Tab WesTab Plus Poly-Vite Pediatric Oral Solution Multi Vitamin and Mineral vitamin MultiVitamin, Iron and Fluoride Drops Venexa B Complex 25mg Vitamin Supplement Virt-Nate Daily Energy Brand B-complex Wellness Formula Orti B Taron-C DHA Manganese 50mg Plus B1 & E Tab Opti-manganese + B1 + C Caplet WesNate DHA Chew.multiple Vits.with Extra C for Children Multiple Vitamins Renate Ultra Enerforce Timed Release B-complex 100 Daily Balance Tab Total Living Concepts Formula One - Tab CitraNatal Assure Vp-pnv-dha Nephrocaps Somavit Brand Vitamins and Minerals Complex Toni Com Liq Chela Potassium Plus Davimet with Iron Revit Plus Cap Children's Chewable With Iron Allbee With C 550 Cap Glyco Lite Ect Multi Enfants Tab Davimet-M Obstetrix EC Lorid Trinatal Ultra Children's Chewable Multi-vitamin Complete With Minerals G.A.S. Complex OB Complete DHA Kids Stuff Tablets NeuroBion Flintstones Multiple Vitamins Elite OB Prenatal Multivitamin Multi-vitamins Dexatran Genicin Vita-Q Iberet 500 NataFort PureVit DualFe Plus Vita Balance 2000 B Complex 500 Tab Cavan Folate OB Folika-NC Super Daily No 2 TL-Care DHA RenaPlex-D Stress B Complex With C,e, Zinc and Copper Multi-12/k1 Pediatric Virt-Vite Plus Vitafer - Liq Stress Tab With Zinc, Copper and Vitamin E Puralor Liqui B Complex Plus Sopalamine 3b Plus Twin Ultra Liquid Grape Flavor Dayavite Niva-Plus RE Nata healthy mamaBE WELL ROUNDED BE WELL ROUNDED Balanced B 125 Srt Inatal Advance Poly-VI-flor B Stress C + Iron & Vite Gemvites Jr Tab Chewable Hemocyte Plus Floravit - Syr Super Pantoplex Multipack II Multivitamin with 1.0 mg Fluoride Vital-D Rx Vitrexyl FolaGent DHA Vitamin B-1 Thiamine HCl 100mg Vitamin B-Complex Cedevita Sugar-free Vitamin Supplement Children's Chewable Multiple Vitamins (chewable Tablets) DaVITE Stress Tablets B Complex W Vit C W Non-med Yeast&liver Tab Childrens Chewable Multivitamins W Iron Vinacal MultiVitamin with Fluoride Chewable Re Ob 90 DHA Pregvit Folic 5 Vyo Cylate - Pwr Spark Cap Harvest Of Values All B Complex Tab B Totum 500 Tonimol Cap Liq Hemarexin Tab Chewable Children's Complete Multivitamins With Essential Minerals Swical-energy 3e Age Central-vite 18 Essential Vitasure Senior Multi One Mega Balance WesCaps Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Formula Fm Vitamins & Minerals Tab Quflora Pediatric Drops M.V.I. Paediatric Megavite Rx Timed Release Vita-vim Srt Trinatal GT Pro Hers Vanilla Vita-worth B-complex Tablets Vitafol Fe Plus Multi Vitamin with Fluoride Livron Plus Ampoule Gestamine Comprimes Chewable Multiple Vit Plus Iron for Children Prenatvite Plus B Complex 50 Vitamin Cap Tricare Prenatal Quick Dissolve Multi #2 B-plex 100 Poly Vi Flor Chewable Tab Stresstabs + Zinc-copper Viva Kids - Tab Hi Potency B Complex W Chelated Minerals Vol-Care Rx Timed Release B-complex 50 Vitrexate FE B-complex Tab Folica BE Omega-3 Rx Complete Thiamine Hydrochloride Triveen-Duo DHA CitraNatal 90 DHA Nephrocaps-QT Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Multiple Vitamins Tab PreTAB Tricare Prenatal 2-part Daily Prenatal Vitamin System Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Multiple Vitamin Tab One A Day Multiple Vit W Minerals Stress B&c Tab Vitafol Plus Vitamin B1 100 mg O-Cal Prenatal Vitamin Vitafol Caplet Virt Vite GT Mvc TM-Vite RX Ziphex Children Choice Multivitamin W Iron Chew Tab Children Choice Multivit Chewable Tab 24 Multivitamins + Minerals Childrens Chewable Vitamins Kanga-kid Vitamins & Iron Multi Vitamin & Minerals Pediatric Infuvite Multiple Vitamins Stress Formula Multiple Vitamins & Minerals Tablets Xvite Vitaflex Dietary Suplement Antlerviron Multi-vitamines Enfants Comprime PrePLUS Paramettes Adults Multi II IV Vi Tab Prenatal Vitamin and Mineral Supplement -tab Adult Formula 50+ Gtf-vitamin-minerals & Pancreatin Tab Integra Plus Dexivite NephPlex Rx Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Children's Chewable Tab Multi Vite Liq Junior Genicin Vita-S SetonET TL-Fluorivite M.V.I. 12 Amladex Foliflex Poly-Vi-Sol Prena1 Plus MultiVitamin with Fluoride Stress B Complex With C, E and Iron Tab Surbex-500 With Zinc Vigo Multivitamins Drops/lozenge Tini-cal Ampoules B-50 Hi Potency B Vitamins Tab NESTABS Prenatal Multi-vitamin/Mineral Supplement Phosthenine Vitamines Et Fer (ampoules Buvable) Multi B Se-Natal Alertonic Multinate DHA Extra Childrens Chew Multi Vitamin Tab Balanced B-complex Vit + Vit C&e Tab Distilpure Msm Formula F L W Vege Swiss One Multivitamin W Chel Mins Tab B-complex 50 THIAMINE HYDROCHLORIDE injection, solution Vitamin B1 Tab 2mg USP One A Day Advance Adults Cyroplex Ply Vi Sol Chewable Tab Folivane-OB PR Natal 430 ec CitraNatal DHA Vitamin B Complex 100 Tab Prenatal Plus Multivitamin Plus DHA MiniCaps Formula Lf Forty Plus Vitamin Supplement Leritone Junior Revit Tab Ventrixyl Vita Vim With Beta Carotene-caplet Women's Formula Trinaz Prenatal RE Prenatal Multivitamin with Iron Xyzbac Lysamine Diet Supp Amp-tab Nitro Vites - Tab Dialyvite with Zinc Kimchi Vitamin chewable multivitamin Essential B Tablets Adeks - Dps Escavite Lq Multivitamins Vita-B-75 Cap Cavan Heme OB Chewable Multiple Vitamins Plus Iron Tab Marnatal F V & M Vitamin and Mineral Supplement Penta-thion Pwr Hylazinc Multra Plex Pregnancy Multivitamin B Virol B-100 Complex Tablets Multiple Vitamins and Minerals Capsules Mebolic Alkadrenergy Tablets Prenatal Vitamins Plus Low Iron Totalvit Plus PR Natal 430 Prim - Royal P.M.T. Super Stress Mega B Plus 1000mg Vit C Tab B-complex Tablets Duet DHA 400 ec Extra Once A Day Stress B Complex With C, E & Iron Liquid B Complex 50 CitraNatal Rx Multitol-M Animal Shapes w/Iron Chewtabs Ferra Naka Plus Vitamins High Potency Vitamin B Complex + C Tab Multi Vitamin Drops with Fluoride and Iron Multitam Prenatal Supplement - Tab Croq-vit Pour Enfants Envirocomplex Select OB Swiss One Multivitamin and Mineral Caplet Nutri-Tab OB Vita B + C 500 Tab Nutra-clear Supravite Pour Enfants Vit B Complex Ctr M-Natal Plus Multi-Vit with Fluoride L-Methyl PNV DHA Revival 1 Tab Vitrexate Complete Natal DHA Multivitamin with Fluoride Hypo Vites Tab Natal PNV One Daily VITES For Kids Only Chewable Multivit. Plus Iron MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement PNV Prenatal Vitamin B1 Tab 100mg Vitamin B1 Tablets 100mg Vitaphil DHA Infant Multivitamin Drops Cavan Prenatal Super Vita Vim Multivitamins and Minerals B-complex With Vitamin C, Biotin, Folic Acid Multi Vitamines - Liq Multi-Vitamin Drops with Fluoride and Iron One A Day Advance Fem Quflora FE Vasula Tab Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitafol One Vitamines Et Mineraux Folic-K RenaPlex CitraNatal Essence T.R.I. B-plex Src Rocky Mountain Multiple Vit and Min Mega Tab WesNatal DHA Complete Vitamin B Complex Plus C 300mg Timed Release OB Complete Petite Children's Chewable Vit and Min Tab Livron Plus Tab Multi-Vit-Flor Revit Multi-vitamins and Minerals Multi-vitamin Dietary Supplement Mycelized Childrens Multi-vitamin Liq Vitranol Fe Vol-Nate Multi Vitamin Drops with Fluoride with Iron Pretrate B1 400mg Ctr Tab Nutrifer Plus Tablets Vitamine Du Groupe B Plus Fer - Liq Prenatal Formula Tab Vasculine Multivitamin Drops with Fluoride VP-Vite Rx PR Natal 400 Pnv-VP-U M.V.I.-12 Zoo Chews Neo-bex Injectable Bal-Care DHA Essential Poly-Vitamin with Fluoride Tonicol Et A-D-C Ampoules/comprimes Fortistress Tab Dexifol Vitalife - Capsule Supravite C 1000 OB Complete Prenatal Multi Vitamin - Mineral Preplus Duet DHA Multivit-liq Vitogen B Stress C600 Chewable Multivitamins Liqui B Complex NovaMV Multivitamin Prenatryl Potassium Plus Vit B Complex Childrens Chewable Multiple Vitamins Flintstones Multiple Vitamins Tab Paramettes Multivits Plus Iron Tab (teens) Pnv Ob DHA Strovite One Caplets Liqui Vita Beminal 500 Tab Iron, Vit & Min Supp Nutra Boost Corvita Vitamin B1 Vp-heme Ob DHA Prenatal and Post Partum Supplement vitaMedMD Rx Plus Iron Folate Plus Childrens Chewable Multiple Vitamins Tab Mega 13 Multivitamin Formula Paramettes Chewable Multivits With Iron Tab B-Combo Tendera-OB Formula D.S. Supravite Stress Avec Vit E Et Fer Allbee With Vitamin C Cap Fibrik Obstetrix DHA Combo Pack Renate DHA Fortaplex Inj Renal Caps Dialysis/Stress Vitamin Supplement Geritol Liquid Se-Care Conceive Soluvit N Magnum-75 Vitamin and Mineral Supplement Bewon Elixir 0.05mg/ml Vol-Tab Rx Fizz Multivitamins for Kids W C Loz Multi-kid Glyco-aide Tab Stress B Complex With C and E Tab Floriva B Complex W Vitamin C Fortis Cap Hormodausse Plus Calc Et D Tab Vitamin B + C Cap Vitamin B Compound W C Tab 500mg Phytoplex B Liq Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Formula B One Daily Vitamin and Mineral Dietary Supplement B 6 Plus Natalvirt 90dha Pregvit B C Antistress Cap Provida OB TL-Folate Vita B Complex Tab Multi Vite Liq Adult B-50 Complex Tab Prometa Strovite Forte Caplet Hemarexin Liquid and Drinkable Ampoules PROTECT IRON Liquid Osteo-force Permathene-12 - Caplet Dothelle DHA Supravite 10ml Ampoule Thiamine HCl Tab 25mg Vitamin B1 Tab 100mg Balanced B-50 B-complex Vitamins Tab Maxi 6 Liq RE Nata OB Vc II Vitogen B Stress C Vit E Zinc & Cop 50 Plus Formula Gm OBTREX DHA Combo Pack Olympian Multi Vit Plus Minerals Tab Zintrexyl-C Multi-force for Women Tab Children's Chewable Multi Vitamins With Iron Tablets Liqui Infant Vitamins Phytovim Cap Complete-RF Prenatal TriphroCaps Vitamin B Compound With Vitamin C Fortis Capsule Dtc Vol-Plus Multivitamins and Minerals for Young Women Multivitamins and Minerals Tablets Poly-VI-sol Drops Childrens Chewable Vitamin Tab Premium Prenatal - Tablets Vitamin B Complex W C 300mg Tab NEONATAL Complete B-complex 100 Infa Drops Multivitamins Multi-Vitamin with Fluoride Stress B Capsules With Vitamin C Ultra Hr Viamon Ampoules Et Comprimes Low Potency B Complex Tab Vitamines Et Mineraux Enfants 970 Men's Biomultiple Vitamin and Mineral Supplement WestGel DHA Vitaphil 90 DHA One Tablet Daily Mens Formula B-complex-50 Tab Derma-force Flintstones Multiple Vitamins Plus Iron Glyco Plus Ect High Potency Multivitamins & Minerals Caplets Multi - N.T.O.x Formula - Tab Prenatal Plus Floriva Plus B Complex 50+ Caplet Stress Formula Multivitamin Tablets USP Cedevita Plus Vitamin Supplement Folet DHA Junior Multi Vitamins - Regular PreferaOB plus DHA tensioSAN HemeNatal OB Multi Vitamin and Fluoride Multivitamins and Minerals - Complete Prenatal Mega Antioxidant L.G.I.T. Balanced B-50 B-complex Vitamins, Timed Rele Mini-B Tab Folika-T Focalgin 90 DHA Se-Natal One Children's Chewable Multi Vit W Iron Spectrum 2 Cap Kanga-kid Multi-vitamin & Mineral Hi Potency B52 B Complex Tab Formula O.C. Multinate DHA Swiss One Virt-Bal DHA Plus VitaPhil Aide Paire OB Plus DHA Stress Forte Plus Lipotropic Factors Vita Vim Multivitamins and Minerals Tab Maxi 10 Tab MI-Vite RX Twin Opti Pwr Vitamin B Complex Women's Biomultiple Vitamin and Mineral Supplement Chewable Multiple Vitamins Tab Prenatol-M Balanced B-100 Timed Release Vitamin B Complex W C Tab Multiple Vitamin Plus Minerals Tab Neonatal Vitamin Mega Capsules Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Complete One-A-day - Tab Neo-vites & Minerals Tab Multiple Vitamins Plus Iron Tab For-2 C-B Complex B-100 Caps Multi Vitamin-mineral Formula Davimet Multivit with Fluoride Vit B Complex Plus Vit C 550mg Children's Chewable Multi-vitamin Folivane-Plus with Ascorbic Acid Precursors Escavite Supravite Bouteille 250ml L.C. Supplement Prenatal Plus Vitamins Vitafant Virt-Caps Formula Gly Vena-Bal DHA Diaplex Neo Vites Tab Adeks Tablets Appedrine Vitamines Pour Bebes Et Enfants Vita-vim - Tab Bugs Bunny and Friends Multiple Vitamins Multi Rol Dialyvite 5000 Dynam Ampoule Et Tablet Nata Komplete Chewable Multiple Vitamins Plus Extra C B-50 Complex Lexazin Polymine Avec Zinc Et Cuivre Vitrexyl plus Iron Feminique W Iron and Calcium Tab Super-pote Vitamin Supplement Carbassist Tablets Multivitamins W Iron Super Stress Capsules Multivitamins W Minerals Extra Strength Cc II Maltlevol Liq Only One - Tablet Relnate DHA Twin Ultra Liquid Orange Flavor Prenatal Plus Iron Se-Plete DHA Stress Ctr Srt Thiamine HCl Injection - Liq 100mg/ml B Plus C 300 mg Chromease Tab Beminal Fortis Elx Men's Multivitamin with 0.25 mg Fluoride NataChew Childrens Chewable Multiple Vitamins Plus Fe C.R.T. X Multivitamin & Mineral Powder Mix Hylavite Multiple Vitamins Plus Iron - Tab B6 Plus Tab Thiamine HCl Inj 100mg/ml Nutra-Z Multi-Vitamin Fluoride and Iron Drops Great Day/am Formula Tab P.R.O. Complex Phytopure PNV Prenatal Plus Multivitamin Lipo-B-C Tab Childrens Chewable Multivitamins Orange Flavored Crystal Chews Tab Vasodyn Tab Thiamine HCl Tab 50mg Multivitamins and Minerals for Young Men Escavite D Children's Chewable Multiple Vitamins - Tab K.L. Vitamin-mineral Complexe B 75mg Multi Pro Multivitamines Omnivex Children's Chewable Multivitamins and Minerals Active OB Reaphirm Plant Source DHA Super Vita-vim With Beta-carotene - Tab Prenate Star Fortamines-10 Comprimes Multi 12 Injection Multi-Vitamin Fluoride Multivitamin & Multimineral Vitamines Et Mineraux Comprimes Folika-V Thiamine HCL 100 mg Maintain Multiple Vitamin & Minerals PNV Ferrous Fumarate Docusate Folic Acid P.N.P. Vitamin Drink Complexe B-75 Premium Prenatal PureFe OB Plus Multivitamins and Minerals for Men Vinate AZ Am Caps Vita-vim With Beta-carotene - Tab Vitamine B1 Tab 100mg USP Ellis Tonic Thiamine HCl 100mg W C 20mg Materna Prenate Elite C-Nate DHA Corvite PM Caps Vitamin B Complex Plus 300mg Vitamin C Prena1 Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Pro His Mint CompleteNate Chewable Infantol Drops Vitramyn Prefera OB plus DHA Super Charged Energy Vitaday Tab Virt-Advance Multi-phyto Capsules Vitabanks Vitamin Tab PNV-First Bewon Elixir C. Vit-min Formula Multi-vitamins With Minerals Multiple Vit Plus Iron Tab Nutrilite Double X Enrich Core Pack - Children Vitamin and Mineral Supplement Vitachrom Gc Dermamed Nutrition for troubled skin Mega-vim 75 With Beta-carotene - Tablets Neonatal19 Abavite Kid's Choice Children's Chewable Vitamins - Tab One Per Day Vitamin and Mineral Dietary Supplement B With C 500 Cap Prevital Tab Balanced B-100 B-complex Vitamins Tab PreNatal 19 Chewable Adult Multivitamins With Minerals Synergistic Manganese Capsules Multi Plex I - Tab Century Complete Classic Swiss One 10 Multivitamin and Mineral Tab Jenliva Cavan Folate DHA Multi Vitamin Plus Iron Q.T. #4 Vitamin and Mineral Dietary Supplement Focalgin CA Meplex T 750 Multi Flow Tablets Multitabs Neomultivite Garfield Chewable Multivits Plus Iron Tab Vit B1 Ctr Srt 100mg Bev B-150 Dalivit Vitamin & Mineral Formula 1 Dietary Supplement Complete Mega B Acti-MN + B1 + C Caplet RE FAC-x Hi Potency Balanced B-100 Complex - Tab Luna Vitamin and Mineral Bar for Women Adult Infuvite Multiple Vitamins Neo-bex Poly-Vi-Flor with Iron Folitin-Z Stressmates Trinatal Rx 1 Vitamin B Complex + C 300mg Cap Fortamines 10 Capsules B Complex W C and B12 Inj Vitafol OB Caplet Multivitamin with fluoride Children's Chewable Multivitamin and Multimineral Stress Complex 600 Avec Vit E Cuivre Zinc Neonatal Plus Vitamin Tandem Plus Thiamine Men's Multi Master Formula Prenatrix FolaMed DHA Vita-Rx Diabetic Vitamin B Plus C 300mg Timed Release Dialyvite Supreme D Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Advanced B & T Formula Supravite Stress Avec Vit E Tricare Prenatal Thrivite Rx Floradix Formula Liq TRONVite Betaxin Liq 100mg/ml Complete Multivitamins and Minerals for Children Edge OB 50 Plus Multiple Vitamins & Minerals Bal-Care DHA Maxum Multi-vite Mor-vites Tab MultiVitamin Drops with Fluoride and Iron V-Natal Maximum Once A Day Virt-PN Kindervites MVC-Fluoride Onccor Folica-V Timed Release B Complex 100 Srt Sun-rype Vitaburst B Complex With C 300mg Thiamine Hydrochloride Inj 100mg/ml B-1 Caps 500mg Multi Vitamins & Minerals Cavan-EC SOD DHA Beminal With C Fortis Pws Multivitamines Plus Fer Pour Enfants (chewable Tablets) Children's Chewable Multivitamin Complete With Minerals Multiple Vitamins - Tablet Somarexin and C 1000 Multivitamines Et Mineraux Junior Regulier Everyday Multiple Vitamins With Iron Hi Potency Stress B Tension With C Lipovite Twin Ultra Liquid Fruit Punch Flavor Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Select-OB Plus DHA Prenatal Supplement Plus DHA Childrens Chewable Tab Synergistic Manganese Cap Neonatal DHA Pnv-OB-dha Prenatvite Complete Women's Change Formula Chela Iron Plus C,b Complex Multivitamine Tricare Prenatal Compleat Vitamin B1 100mg Tablet Multiple Vitamins With Iron Concept OB O-Cal FA multivitamin Flintstones W Extra C Tab NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Prenatal Vitamin and Mineral Supplement C-force Virt-Pn PNV-Select Multra With Iron Prenatal Vitamins and Minerals Tablets Vital Be-100 Vyqua Twin G.F. Powder Stress Vitamin B With C Complex Tablets Nephron FA Doctor's Choice Brand for Men WesCap-C-DHA Garfield Chewable Multivitamins Tab Megavites Tab Multi Vitamin, Iron and Fluoride Bev 29 Tab Thiamine Hydrochloride Inj 100mg/ml USP Novel Vita Virt Nate B-plus - Tab Mega Vitaminerals Prenatal Vi-min Complexe B Compose 75 TriAdvance HemeNatal OB plus DHA Original Bioscal Forte Multi-vitamin Supplement Capsules Stress Formula Vit B With C Complex Virt-C DHA Provida DHA Biovim Tab Livita Adults Kenwood Liquid Supplement B-plex Chewable Multiple Vitamins for Children Multi Vitamin Drops with Fluoride Reno Caps B Complex With C 550mg Flinstones Multiple Plus Iron Poly-Vi-Flor Methaver
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682