DrugBank ID DB00878 Name Chlorhexidine Groups withdrawn approved vet_approved Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms Chlorhexidine acetate Chlorhexidinum N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Chlorhexidine Cloresidina
Chlorhexidine hydrochloride 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) Chlorhexidin Chlorhexidine gluconate Clorhexidina more Brand Names Dr. Zheng s acteriostatic gel Chlorhexidine Gluconate Baxedin Pre-OP Hygienipak 4% Chg Foaming Skin Cleanser Anti Mucedine Feminine Wash
3M SoluPrep BD E-Z Scrub Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Purell CS Foam Handwash 2% CHG Hibitane Skin Cleanser 2% Chloraprep Liq 0.5% Gum Paroex Dexidin Liq 4% Germi-stat 2% Foaming Liquid Germi Stat Gel 2% Dexidin 2 Detergent Chloraprep Swabsticks Prevantics Maxi Swabstick HYDROGEL ESSENCE Antimicrobial Virginal Gel. Dyna-hex 2 Selpak Antibacterial Wet Wipes Soluprep AQ Swab Surgical and healthcare personnel hand antiseptic with moisturizers Hand Sanitizer Pre-moistened Towelette Hibistat Scrub Care Exidine -4 CHG Hand wipes Loris I.V. Pro - Prefilled Applicator With Solution Oral Cleansing and Suctioning System, q2 Alcohol Antibacterial Wipes Antimicrobial Skin Cleanser Soluprep Antiseptic Skin Cleanser Preoperative Kit Microban Medical Q2 Oral Care Kit with CHG Hand Sanitizer Biokaab Ic-gel PerioChip Baxedin 2% - 70% 3M Avagard Antiseptic Body Cleanser Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps Antiseptic Foam Handwash Akilgeld Hand Sanitizer Periogard Hibitane Skin Cleanser 4% Hygienipak 4% Chg Skin Cleanser Prevantics swabstick Chlorhexidine Gluconate, 0.12% Oral Rinse Dexidin 0.5 Solution Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Hexicinide Chlorhexidine 4% Antiseptic Hand Wash DermacinRx Surgical PharmaPak Sunberry Rinse free Hand Sanitizer Plant Herb Based Bacteriostatic Feminine Wash Steri-stat Tincture (tinted) Antis Prep Gel Spray On Plastic Bandage Non-aerosol Hospicare 40R Adult Body Wipes ICEKING Skin Expert Refreshing Body Roller Soluprep AQ QCare Rx Oral Cleansing and Suctioning System, Q4 Soluprep AQ Sponge B-good Hand and Skin Disinfecting Agent Provon Antiseptic Lotion Soap With 2% Chg Antiseptic Lotion Soap 2% PhysiciansCare Eyewash Station Additive Concentrate Cida-stat Liq Pro-dentx Chlorhexidene Oral Rinse NuSurgePak Surgical Prep/CarePak PS1 Aciurgy Pack Antiseptic Cleansing Wipes Oronine H Ointment 1% Chlorhexidine Gluconate 0.12% Oral Rinse Prevora Stage 1 Baxedin Liq 20% Baxedin Chlorhexidine Gluconate Solution 0.75% Antiseptic Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Serdaen Peridex Oral Rinse 0.12% Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol 3m Soluprep Sponge Bactoshield CHG Chlorhexidine Gluconate Alcohol Disinfectant Wipes Liszt Hand sanitizer without washing Hexirex Antiseptic Skin Cleanser Freeman Packing Alcohol Wipe Chlorhexidine Gluconate Solution 0.05% BD E-Z Scrub 107 Soluprep Qd Swab Sky Oral Rinse Cardinal Health Antiseptic Skin Cleanser Tai Yu Ling Antibacterial Sprays 10mL Stanhexidine Red Tincture 0.5% Laura Line Antibacterial Cream Soap 2% Aplicare Chlorhexidine Gluconate 2% Solution Hibiclens Chlorhexidine 0.5% Liq Aplicare Antiseptic Chlorhexidine Gluconate Steri-stat Liq 20% Chlorhexidine Gluconate 0.12% Oral Rinse, USP Antibacterial Protective Hand Motherwort Herb Feminine Antibacterial Gels Periogard Alcohol Free QCare Rx Petite Oral Cleansing and Suctioning System Dyural LM- C Stanhexidine 20% Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Betasept Flamazine C (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant Ostar Antimicrobial Hand Soap 2% - Liquid Pre-Scrub II Surgical Hand Scrub QCare Rx Oral Cleansing and Suctioning System, Q2 Foaming Hand Wash Soluprep E-Z Scrub 107 CLIP Liquid Sanitizer Steri-stat Liq 2.0% Gelato Chlorohexidine KleerSight Dyna-Hex 75 Antiseptic Skin Cleanser Akilspray Hand Sanitizer Hibiclens for Georgia Pacific Protective Hand Scrub Stat 4 Foam Liq Ultrastat CliniClean Oro-clense LARA MED Antibacterial Wet Wipes Bactoshield Chg 4% PMS-chlorhexidine KIMVENT ORAL CARE Q4 Kit WITH CHG Skin antisepsis, oral cleansing, nasal antisepsis 3M SoluPrep S Soluprep Qd Wipe HandSoap Smart San CHG Chlorhexidine gluconate DermacinRx Surgical ComboPak First Aid Antiseptic Skin Cleanser Hand Wipes Solunet C Brosse 4% E-Z Scrub 747 4% Chlorhexidine Chlorhexseptic-liq 0.5mg/ml Hygenipak 2% Chg Foaming Skin Cleanser Bioprep Liq Dyna-Hex 2 Spectro Gram 2 Skin Cleanser Wart Remover Ointment. Loris - I.V. Disinfectant Fabric Wash Prevantics Swab Quick-Drying Hand Sanitizer Zappy Ultimate Antiseptic Wipes Chlorhexidine Gluconante Seaqua X Rougier Clean Derm Chlorhexidine-cetrimide Soltn Conc Soluprep Antiseptic Skin Cleanser Sponge Endure 420 Cida-Stat Hexifoam-skin Disinfectant Aer 1% Betalido-C Loris 2% Chg Wipe/serviette Mlk F4-C Peridex Oral Rinse QCare Rx Oral Cleansing and Suctioning System Smart Sense Antiseptic Skin Cleanser Avidene Surgical Scrub Cardinal Health Paroex Euro-chlorhexidine Rugby Antiseptic Skin Cleanser E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Dr. Dean Hands-free skin sanitizer Noble 75% Alcohol Wipes Hygienium Spectro Tar Antiseptic Shampoo Dermawerx Surgical Plus Pak Cida-stat Foam DermacinRx Clorhexacin Bactoshield Scrub Steri-clean Rouhex G Liq 2% Dyural 80 LM-C Savlon Hospital Concentrate Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Chlorhexidine Solution Bactoshield Chg 2% Scrub-stat IV 4% Scrub, Scrub-Stat Purell Antimicrobial Foam Handwash 2% Chg Ezy-TM Quick-drying rinse-free hand skin disinfectant Soluprep Wipe Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Foam Safe Calgon Vestal 2% Chg Antimicrob.skin Cleans. Eyewash Station Additive Concentrate Surgical Continuum System Spray On Plastic Bandage Aerosol ChloraPrep One-Step Rougier Vap-chlorhexidine Gluconate 2% W/V Zedoary Oils Feminine Antibacterial Gels Chlora-cleanze Kimvent Oral Care Q2 Kit with CHG Purmist Antiseptic Solution JIANLIANG Antibacterial Sprays 10mL Pre and Post Sx Pouch Chlorhexidine Gluconate Applicator Soft Care Antiseptic Hand Soap Foaming Chlorhexidine Gluconate Hibiclens Antiseptic/antimicrobial Skin Cleanser Anti-bac Hand PS2 Aciurgy Pack Soluprep Applicator Hygenipak 2% Chg Skin Cleanser Disinfectant Wet Tissues Antiseptic Cleanser Solution Soluprep Ld Sponge Dexidin 20 X-pur Chlorhexidine Soluprep Swab Major Oral Rinse PMS-chlorhexidine Without Alcohol Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Endure 400 Scrub-Stat 4 Scrub, Scrub-Stat, Foam Safe, Micro-Guard Scrub Care Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes Hibitane Skin Cleanser Henry Schein Antimicrobial Skin Cleanser Chlorhexidine Liq 0.05% Bactoshield CHG Chlorhexidine Gluconate Solution Germi-stat Prep Gel Dexidin 2 Solution Chlorhexidine Gluconate Solution USP 20% Provon Antimicrobial Foam Handwash Foam Care Chg Surgical Hand Scrub Yu Ding Antibacterial Sprays 10mL Loris I.V. Pro - Swabstick Chlorhexidine and Isopropyl Alcohol Swabsticks CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Steri-stat Liq 4.0% Soluprep AQ Applicator Dyna-hex 4 Hibistat Germicidal Hand Rinse Peridex Burn O Sol Spray Loris I.V. Pro - Sponge Chlorhexidine and Isopropyl Alcohol Prep Pads DEQGEL Advanced Hand Sanitizer Germi Stat Gel 4% Purell Antimicrobial Foam Antiseptic First Aid Spray Halyard Chlorhexidine Gluconate Dr. Luke Molluscum Wart Remover Instillagel Dyna-Hex 4 (Fruli) Quick-Dry Disposable Hand Sanitizer Chlorhexidine 2% Antiseptic Hand Wash Dexlido M-C Oris Chx Germi-stat 0.5% Antiseptic Prep Gel Sanital Antibacterial Hand Soap Antiseptic Skin Cleanser Exidine-2 CHG Liquivida Hydration Chloraprep DASH Chlorhexidine Gluconate 0.12% Oral Rinse SANIDEP Advanced Sanitizer with Organic Extracts Scrub Care Exidine-2 CHG ReadyPrep CHG Bactoshield CHG Soluprep Qd Solution NUPRO Chlorhexidine Gluconate Bioprep Wart removal Perioselect Antimicrobial Sol 0.12% Soft Care 2% Chg Antimicrobial Skin Cleanser Rouhex G 20% Antimicrobial Foam Handwash Foaming Hand Antiseptic With Chg 2% Salvesept Crm ChloraPrep Swabstick Hand Sanitizer Gel Biokaab SAITENM Health Wet wipes Prevantics Swabstick WhyteDerm SurgiPak Soluprep AQ Wipe Jisberry Hand Sanitizer Stanhexidine 2% With Isopropyl Alcohol 4% Sterixin 0.05% Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Savlodil Scrub-Stat Bacti-stat Chg Rouhex G 4% Hibidil Bactigras Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Dr. Luke Wart Remover Oro Clear Laura Line Chlorhexidine Antiseptic Soap Avagard Chg Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Dermsafe Pc Disinfectant Spray(Speedy effect type) Loris 2% Chg Solution Dermawerx Surgical PrePak Oral Cleansing and Suctioning System, q4 Hibitane Skin Cleanser Liq 4% Stanhexidine 4% With Isopropyl Alcohol 4% Wart Removal Pen Sterigel Plus Chinese Herb Essence Bacteriostatic Feminine Wash Septi-san Stat Touch 2 Antimicrobial Skin Cleanser Chlorhexidine Alcohol Free Calgon Vestal 4% Chg Antimicrob.skin Cleans. Chlorhexidine Gluconate Oral Rinse Foster and Thrive Periogard (Chlorhexidine Gluconate) more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
