DrugBank ID DB00878 Name Chlorhexidine Groups vet_approved withdrawn approved Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms Chlorhexidine gluconate Cloresidina Clorhexidina Chlorhexidin Chlorhexidine acetate
Chlorhexidine Chlorhexidine hydrochloride 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) Chlorhexidinum N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide more Brand Names Zedoary Oils Feminine Antibacterial Gels Foaming Chlorhexidine Gluconate Soluprep AQ Skin antisepsis, oral cleansing, nasal antisepsis Peridex Oral Rinse
Spray On Plastic Bandage Non-aerosol Purell CS Foam Handwash 2% CHG Oro-clense First Aid Antiseptic Skin Cleanser Quick-drying rinse-free hand skin disinfectant Hygienium Selpak Antibacterial Wet Wipes Chlorhexidine Gluconate Solution 0.75% Antiseptic Endure 420 Cida-Stat Hibitane Skin Cleanser Liq 4% Chlorhexidine Gluconate Solution 0.05% Anti Mucedine Feminine Wash Hexicinide Sterixin 0.05% Steri-clean Loris I.V. Pro - Swabstick Dermawerx Surgical Plus Pak ChloraPrep Swabstick Loris I.V. Pro - Prefilled Applicator With Solution Antiseptic Solution Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Microban Medical Oral Cleansing and Suctioning System, q4 Chlorhexidine Gluconate Oral Rinse Dyna-Hex 2 Kimvent Oral Care Q2 Kit with CHG CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse QCare Rx Petite Oral Cleansing and Suctioning System Endure 400 Scrub-Stat 4 Periogard Major Oral Rinse Antiseptic Foam Handwash Soluprep AQ Sponge Spray On Plastic Bandage Aerosol Burn O Sol Spray Wart removal Provon Antimicrobial Foam Handwash Chlorhexidine and Isopropyl Alcohol Swabsticks DermacinRx Surgical PharmaPak WhyteDerm SurgiPak Dyural 80 LM-C Rouhex G 4% Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Bacti-stat Chg SAITENM Health Wet wipes JIANLIANG Antibacterial Sprays 10mL Dyna-hex 4 Chlorhexidine Gluconate Applicator Dr. Zheng s acteriostatic gel Germi-stat 0.5% Antiseptic Prep Gel Alcohol Disinfectant Wipes Smart San CHG Provon Antiseptic Lotion Soap With 2% Chg Chlorhexidine gluconate Hibitane Skin Cleanser 2% DASH Chlorhexidine Gluconate 0.12% Oral Rinse BD E-Z Scrub 107 Hibitane Skin Cleanser PS1 Aciurgy Pack Mlk F4-C Hibiclens for Georgia Pacific Germi-stat 2% Foaming Liquid Spectro Gram 2 Skin Cleanser Wart Removal Pen Gum Paroex Ic-gel Soluprep Antiseptic Skin Cleanser Sponge Antiseptic Cleanser Solution Disinfectant Fabric Wash Dermsafe Pc Purell Antimicrobial Foam Scrub, Scrub-Stat ChloraPrep One-Step Hand Wipes Periogard (Chlorhexidine Gluconate) Oronine H Ointment 1% Soluprep Ld Sponge Quick-Drying Hand Sanitizer Perioselect Antimicrobial Sol 0.12% Hand Sanitizer Biokaab Soluprep AQ Wipe 3M SoluPrep S PMS-chlorhexidine Without Alcohol Soluprep AQ Applicator Rugby Antiseptic Skin Cleanser Scrub, Scrub-Stat, Foam Safe, Micro-Guard Dyna-Hex 4 Flamazine C Smart Sense Antiseptic Skin Cleanser Sky Oral Rinse Hygenipak 2% Chg Foaming Skin Cleanser Betalido-C Aplicare Antiseptic Chlorhexidine Gluconate Hibistat Germicidal Hand Rinse Pre-Scrub II Surgical Hand Scrub Peridex Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Dermawerx Surgical PrePak Zappy Ultimate Antiseptic Wipes Disinfectant Wet Tissues Purmist Soluprep Applicator Paroex Rougier Clean Derm Oro Clear Periogard Alcohol Free Avagard Chg Surgical and healthcare personnel hand antiseptic with moisturizers Dyna-hex 2 Chlorhexidine 0.5% Liq Chlorhexidine Gluconante Calgon Vestal 4% Chg Antimicrob.skin Cleans. 3M SoluPrep Q2 Oral Care Kit with CHG Germi Stat Gel 2% Chlorhexidine and Isopropyl Alcohol Prep Pads Henry Schein Antimicrobial Skin Cleanser Dexidin 2 Solution Peridex Oral Rinse 0.12% Bactoshield CHG Chlorhexidine Gluconate Solution Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Loris - I.V. Antiseptic Lotion Soap 2% CLIP Liquid Sanitizer Bioprep Liq Antiseptic First Aid Spray Cardinal Health QCare Rx Oral Cleansing and Suctioning System, Q2 Scrub Care Exidine -4 CHG Chlorhexidine-cetrimide Soltn Conc SANIDEP Advanced Sanitizer with Organic Extracts Soft Care Antiseptic Hand Soap Jisberry Hand Sanitizer PMS-chlorhexidine Hexirex Antiseptic Skin Cleanser CliniClean Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Stat Touch 2 Antimicrobial Skin Cleanser Wart Remover Ointment. Hibiclens Bactoshield CHG DermacinRx Clorhexacin NuSurgePak Surgical Prep/CarePak Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Baxedin Liq 20% Hibistat Liquivida Hydration (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant Dexidin 20 Antimicrobial Skin Cleanser Antiseptic Skin Cleanser Exidine-2 CHG Bactoshield Chlora-cleanze Motherwort Herb Feminine Antibacterial Gels HandSoap Chlorhexidine Gluconate Solution USP 20% Bactigras E-Z Scrub 747 4% Bactoshield Chg 4% Prevantics Swabstick Dexidin 0.5 Solution Baxedin Pre-OP PerioChip Chlorhexidine Gluconate, 0.12% Oral Rinse Solution 3m Soluprep Sponge Halyard Chlorhexidine Gluconate Laura Line Antibacterial Cream Soap 2% ICEKING Skin Expert Refreshing Body Roller Akilspray Hand Sanitizer Loris 2% Chg Solution Seaqua X Hibitane Skin Cleanser 4% Alcohol Antibacterial Wipes Scrub Stat 4 Foam Liq Bactoshield Chg 2% Dexlido M-C Foaming Hand Antiseptic With Chg 2% Stanhexidine 20% Loris 2% Chg Wipe/serviette Betasept Chlorhexidine Gluconate 0.12% Oral Rinse, USP Germi Stat Gel 4% Foaming Hand Wash Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Chloraprep Swabsticks PhysiciansCare Eyewash Station Additive Concentrate Cardinal Health Antiseptic Skin Cleanser Yu Ding Antibacterial Sprays 10mL Gelato Chlorohexidine Chlorhexidine Gluconate 0.12% Oral Rinse Scrub-Stat Stanhexidine Red Tincture 0.5% Soft Care 2% Chg Antimicrobial Skin Cleanser Eyewash Station Additive Concentrate Anti-bac Hand Soluprep Wipe Chlorhexidine Hexifoam-skin Disinfectant Aer 1% Akilgeld Hand Sanitizer Antimicrobial Foam Handwash Antibacterial Protective Hand E-Z Scrub 107 Euro-chlorhexidine Disinfectant Spray(Speedy effect type) Dyural LM- C Oris Chx Soluprep Qd Wipe Purell Antimicrobial Foam Handwash 2% Chg NUPRO Chlorhexidine Gluconate Salvesept Crm Hand wipes Chinese Herb Essence Bacteriostatic Feminine Wash Chlorhexidine 4% Antiseptic Hand Wash Protective Hand Scrub Care Exidine-2 CHG Prevantics Swab Instillagel Cida-stat Foam Serdaen Septi-san E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Hygienipak 4% Chg Foaming Skin Cleanser Soluprep AQ Swab Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Ezy-TM Steri-stat Liq 4.0% Chlorhexidine Gluconate Hand Sanitizer Gel Biokaab Hibidil Chlorhexidine Gluconate, 0.12% Oral Rinse QCare Rx Oral Cleansing and Suctioning System, Q4 Freeman Packing Alcohol Wipe Soluprep Qd Solution Foam Care Chg Surgical Hand Scrub Ostar Antimicrobial Hand Soap 2% - Liquid DEQGEL Advanced Hand Sanitizer Chlorhexidine Liq 0.05% Dexidin 2 Detergent Dr. Luke Wart Remover Chlorhexseptic-liq 0.5mg/ml Surgical Continuum System Plant Herb Based Bacteriostatic Feminine Wash Prevantics Maxi Swabstick PS2 Aciurgy Pack Savlon Hospital Concentrate Dyna-Hex 75 Soluprep Qd Swab Scrub Dr. Luke Molluscum Wart Remover Antiseptic Cleansing Wipes Chlorhexidine Alcohol Free Prevantics swabstick Steri-stat Liq 2.0% Pre and Post Sx Pouch Loris I.V. Pro - Sponge Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps QCare Rx Oral Cleansing and Suctioning System Foster and Thrive Steri-stat Tincture (tinted) Antis Prep Gel Rouhex G 20% Chlorhexidine Solution Savlodil X-pur Chlorhexidine Chlorhexidine 2% Antiseptic Hand Wash Chloraprep Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes Hibiclens Antiseptic/antimicrobial Skin Cleanser Prevora Stage 1 B-good Hand and Skin Disinfecting Agent Antiseptic Body Cleanser Dexidin Liq 4% Hand Sanitizer Baxedin 2% - 70% Stanhexidine 2% With Isopropyl Alcohol 4% (Fruli) Quick-Dry Disposable Hand Sanitizer LARA MED Antibacterial Wet Wipes KleerSight Soluprep Antiseptic Skin Cleanser Preoperative Kit Hospicare 40R Adult Body Wipes Solunet C Brosse 4% Tai Yu Ling Antibacterial Sprays 10mL Hygienipak 4% Chg Skin Cleanser Liszt Hand sanitizer without washing Bactoshield CHG Chlorhexidine Gluconate ReadyPrep CHG Rougier Vap-chlorhexidine Gluconate 2% W/V Germi-stat Prep Gel Foam Safe Pre-moistened Towelette Antiseptic Skin Cleanser Soluprep Spectro Tar Antiseptic Shampoo Dr. Dean Hygenipak 2% Chg Skin Cleanser Avidene Surgical Scrub Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol Calgon Vestal 2% Chg Antimicrob.skin Cleans. Bioprep Ultrastat Hands-free skin sanitizer Aplicare Chlorhexidine Gluconate 2% Solution Scrub-stat IV 4% Stanhexidine 4% With Isopropyl Alcohol 4% Laura Line Chlorhexidine Antiseptic Soap Sunberry Rinse free Hand Sanitizer Cida-stat Liq Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Baxedin BD E-Z Scrub Sterigel Plus KIMVENT ORAL CARE Q4 Kit WITH CHG Rouhex G Liq 2% Soluprep Swab Noble 75% Alcohol Wipes HYDROGEL ESSENCE Antimicrobial Virginal Gel. Pro-dentx Chlorhexidene Oral Rinse Scrub Care Sanital Antibacterial Hand Soap 3M Avagard DermacinRx Surgical ComboPak Steri-stat Liq 20% Chloraprep Liq 0.5% Oral Cleansing and Suctioning System, q2 more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
