Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
(S)-lysine
Lysine hydrochloride
Lysine dihydrate
Lysine acid
(S)-2,6-diaminohexanoic acid
6-ammonio-L-norleucine
Lysine monohydrate
L-Lysine
L-lys
Lysina
(S)-α,ε-diaminocaproic acid
Lysine acetate
L-Lysin
LYS
Lysine
Lysinum
L-2,6-Diaminocaproic acid
Brand Names
Xyzmune
Aminosyn-PF 10%
Vamin N
Effervescent Potassium Chloride
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn II
Olimel 4.4%
Travasol
Olimel 5.7% E
Aminosyn 8.5%
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Aminosyn II in Dextrose
Travasol Inj Without Electrolytes 5.5%
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Olimel 5.7%
Aminosyn II 8.5% Injection
20% Prosol
Aminosyn II 8.5% With 50% Dextrose
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn-PF
ProSol
Renamin (amino Acids) Injection
Premasol - sulfite-free (Amino Acid)
Nutrineal Pd4
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Aminosyn 10% W Electrolytes
TrophAmine
Imubolic
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Travasol Inj Without Electrolytes 8.5%
Aminosyn II 10% With Electrolytes
Essepna
Aminosyn II with Electrolytes
Clinimix E
8.5% Freamine III
NephrAmine
Primene 10%-liq IV
Kabiven
Travasol Amino Acid Inj 5.5%
Synthamin
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn Sulfite Free
Smofkabiven
RenAmin
Aminosyn 7%
Plenamine
Smofkabiven Extra Nitrogen
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Olimel 4.4% E
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Nephramine Liq IV
Smofkabiven Electrolyte Free
Primene
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn RF
Aminosyn RF Injection
Novamine
Olimel 7.6% E
HepatAmine
Aminosyn
Aminosyn II and Dextrose
Aminosyn 8.5% Injection With Electrolytes
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Clinimix
Aminosyn 5%
Travasol Amino Acid Inj 8.5%
Aminosyn 3.5% M
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Lysakare
Aminosyn-PF 7%
ProcalAmine
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Perikabiven
Aminosyn II 5% Inj
Aminosyn II 7% Injection
Vamin 18 Electrolyte-free
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn II 7% With 50% Dextrose
Olimel 7.6%
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
FreAmine III
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Periolimel 2.5% E
Aminosyn II In Dextrose Injection
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Olimel 3.3% E
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Aminosyn II with Electrolytes in Dextrose with Calcium
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Hepatasol
FreAmine HBC
Primene 10%
Smofkabiven Peripheral
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Travasol E
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Aminosyn II 7% With 10% Dextrose
Clinisol
Aminosyn HF
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
