PDB-101 Focus: Peak Performance

12/15 

Since 2014, PDB-101 has focused on different topics to help build a collection molecular stories around a particular theme. Past topics have included cancer and diabetes.

In 2025, PDB-101 has been highlighting the structural stories of Peak Performance: the structural biology of athletics and well-being.

Athletes require bodies that are the best that is possible, all the way from molecules to muscles. By understanding the structure and function of our molecules, athletes can ensure that they are performing at their peak. This knowledge also informs the ways that we all can live our best lives, at all stages of our lives.

Visit the PDB-101 Peak Performance Browser for resources such as:

Vitamin D is converted into a hormone in the kidneys and is distributed throughout the body, where it notably governs intestinal calcium absorption and bone maintenance. This hormone (magenta) binds to Vitamin D receptors (green), which contain two distinct domains: one that binds to the hormone and one that binds to DNA. These receptor units team up with the 9-cis-retinoic acid receptor (blue) to interact with DNA, ultimately activating or repressing synthesis of crucial proteins involved in calcium regulation.
Visit the 2025 Calendar: The Structural Biology of Nutrition to learn more.
Illustration by RCSB PDB intern Xinyi Christine Zhang.

Learn more in the article Molecule of the Month: Vitamin D Receptor

News Index

• 11/11 PDB-101 Focus: Peak Performance

• 11/06 Register Now for Webinar: Exploring Integrative Structures with RCSB.org

• 11/06 Education Corner: Cambridge Structural Database

• 11/04 Powering a New Era in Structural Biology

• 11/02 Register Now for Webinar: Exploring the Workhorses of Biotechnology

• 10/30 Coming Soon: Remediation of Metalloprotein-containing PDB Entries and CCDs

• 10/28 Watch Molecules in Motion

• 10/21 Explore Green Fluorescent Protein

• 10/19 Happy Birthday, PDB!

• 10/16 Happy Birthday, Irving Geis

• 10/14 PDB-101 Focus: Peak Performance

• 10/08 Explore Structural Biology with CSMs

• 10/07 Register for the Nov 24 Virtual Office Hour on Exploring CSMs at RCSB.org

• 10/06 Fall Newsletter Published

• 10/05 Structural Biology and Nobel Prizes

• 10/02 Register for the Oct 30 Virtual Office Hour on Structure Summary Pages

• 10/01 Video: Vitamin A and Vision

• 09/30 Explore Inktober SciArt images

• 09/30 Register Now for Webinar: Exploring the Workhorses of Biotechnology

• 09/28 Watch the Pairwise Alignment Tool Office Hour

• 09/23 wwPDB News: Introducing the first 3DEM Model-Map percentile slider to the wwPDB validation report

• 09/23 Browse Protein Structure Prediction at PDB-101

• 09/23 Register for the Sept 25 Virtual Office Hour on PDB Policies

• 09/22 wwPDB News: MolViewSpec: describe, share, and reproduce Mol* molecular scenes

• 09/16 Register Now for Webinar: Exploring Integrative Structures with RCSB.org

• 09/15 PDB-101 Focus: Peak Performance

• 09/08 RCSB.org is Powered by AWS

• 09/02 Register for the Oct 30 Virtual Office Hour on Structure Summary Pages

• 09/02 Video: Caffeine and Adenosine

• 08/26 PDB-101: Global Health

• 08/25 Register Now for Webinar: Searching the PDB for high-quality ligand-bound structures

• 08/21 Poster Prize Awarded at ISMB/ECCB 2025

• 08/19 Announcement: Ligand Expo To Be Retired in 2025

• 08/19 PDB-101 Focus: Peak Performance

• 08/18 wwPDB News: Paper Published: 3DEM Structure-Map Validation Recommendations

• 08/14 Poster Prize Awarded at ACA 2025

• 08/12 Paper Published: PDB-IHM

• 08/11 Register for the Sept 25 Virtual Office Hour on PDB Policies

• 08/05 Register for the Aug 11 Virtual Office Hour on Pairwise Alignment

• 08/05 Paper Published: rcsb-api

• 08/01 August 2 is National Coloring Book Day

• 07/29 Register Now for Webinar: Searching the PDB for high-quality ligand-bound structures

• 07/29 Celebrate World RNA Day on August 1 with Eterna

• 07/22 Prepare Depositions Using pdb_extract

• 07/22 PDB-101 Focus: Peak Performance

• 07/18 Meet the RCSB PDB at ACA 75

• 07/15 wwPDB News: Transitioning to PDBx/mmCIF and Extended PDB IDs

• 07/15 Color the Diverse 3D Shapes Studied by Crystallographers

• 07/08 Summer Newsletter Published

• 07/03 Register for the Aug 11 Virtual Office Hour on Pairwise Alignment

• 07/01 Download New Poster: CSMs and PDB Structures

• 07/01 Watch the Webinar: Python For Cheminformatics-Driven Molecular Docking

• 06/25 wwPDB News: Extension to EMDB Accession Codes

• 06/24 Python Toolkit for Accessing RCSB.org Search and Data APIs

• 06/19 Watch: Deep Dive into Computed Structure Model Exploration at RCSB.org

• 06/16 Register for the ACA Workshop on PDB Deposition

• 06/13 Download an image of H5N1

• 06/10 PDB-101 Focus: Peak Performance

• 06/09 Watch the Sequence Annotations Viewer Office Hour

• 06/03 Electron Density Maps and Coefficient Files

• 05/28 Explore Integrative Structures at RCSB.org

• 05/26 Annual Report Published

• 05/22 Register Now for Tutorial: Introduction to Molecular Animation

• 05/20 Video: Immunology and Cancer

• 05/19 Announcement: Ligand Expo To Be Retired in 2025

• 05/19 Access Computed Structure Model Annotations

• 05/16 PDB-101 Focus: Peak Performance

• 05/13 Paper Published: A new chapter for Molecule of the Month

• 05/12 Education Corner: BASIL, RCSB Protein Data Bank, and the NSF

• 05/06 Watch the Webinar: Seeing Bird Flu in 3D

• 05/06 wwPDB News: Poster Prize Awarded at ASBMB

• 05/04 Commemorating 75 Years of Discovery and Innovation at the NSF

• 05/01 Toggle to "Opt-in" to Access Computed Structure Models Alongside PDB Data

• 04/28 Watch the Webinar: Streamlining Access to RCSB PDB APIs with Python

• 04/25 Education Corner: Paper Nucleic Acid Models for Hands-on Education

• 04/22 wwPDB Validation Reports Accessible via API

• 04/22 Celebrate DNA Day on April 25

• 04/18 April 22 is Earth Day

• 04/16 wwPDB News: Download Snapshots of the PDB Core Archive via HTTPS, SYNC, RSYNC, or FTP

• 04/15 Introducing Extended PDB IDs at RCSB.org

• 04/15 Paper Published: Visualizing and analyzing 3D biomolecular structures using Mol*

• 04/11 Meet RCSB PDB at ASBMB

• 04/08 Sequence Annotations Viewer: Geometry Validation

• 04/07 Spring Newsletter Published

• 04/03 PDB-101 Focus: Peak Performance

• 04/01 Paper Published: PDB and a transformative impact on science and society

• 03/27 Register Now for Crash Course: Python For Cheminformatics-Driven Molecular Docking

• 03/27 Guide to Understanding PDB Data: Computed Structure Models

• 03/24 Developers: Switch to Sequence Coordinates Service by May 31, 2025

• 03/20 Meet RCSB PDB at the American Chemical Society Meeting

• 03/19 March 24 is World TB Day

• 03/15 PDB-101 Focus: Peak Performance

• 03/11 wwPDB News: Poster Prize Awarded at The Biophysical Society Meeting

• 03/10 wwPDB News: New version of PDB-IHM validation reports now include assessments of crosslinking mass spectrometry-based structure models

• 03/09 March 10-16: Brain Awareness Week

• 03/06 Register for the April 10 Virtual Office Hour on Sequence Annotations Viewer

• 03/05 IUCr2026 Awaits

• 03/04 Take the User Survey on Statistics and Win

• 03/04 Molecular Landscapes

• 03/03 Register for the May 8 Workshop on PDB Deposition

• 03/03 Register for March Training Events

• 03/02 March 4 is International HPV Awareness Day

• 02/25 Register for the April 7 Virtual Office Hour on Depositing IHM Data

• 02/25 Paper Published: From two epidemics to the global pandemic to mRNA vaccines and Paxlovid

• 02/21 Paper Published: Impact of the PDB on drug approvals

• 02/17 PDB-101 Focus: Peak Performance

• 02/17 Register Now for Webinar on API Access with Python

• 02/13 Meet RCSB PDB at The Biophysical Society Meeting

• 02/10 Register for the March 13 Virtual Office Hour on Supporting Extended PDB IDs

• 02/09 Molecular Valentines

• 02/05 Behind Molecule of the Month

• 02/02 Register Now for Webinar on Seeing Bird Flu in 3D

• 02/01 February 4 is World Cancer Day

• 01/28 Frontiers in Data Panel Webinar: Preparing Structural Science Data for 2085

• 01/23 Award-Winning Image

• 01/23 Developers: Collaborate with RCSB PDB at Rutgers

• 01/21 Watch the Webinar: Unlock Rapid Analyses Across the Whole PDB Using BinaryCIF

• 01/19 January is Cervical Cancer Awareness Month

• 01/17 Undergrads: Spend your summer with RCSB PDB

• 01/16 wwPDB News: PDB-Dev now PDB-IHM

• 01/16 Top Molecules of the Month in 2024

• 01/14 Winter Newsletter Published

• 01/12 Paper Published: Updated resources for exploring PDB structures and Computed Structure Models

• 01/09 Celebrate #NationalMilkDay

• 01/05 wwPDB News: Time-stamped Copies of PDB and EMDB Archives

• 01/05 Molecule of the Month: Celebrating 25 Years of Storytelling and Announcing New Beginnings