Download MendeleyCrystal structure of human CD38: Cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase
Shi, W., Yang, T., Almo, S.C., Schramm, V.L., Sauve, A.To be published.
1ZVM | pdb_00001zvm
Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase
- PDB DOI: https://doi.org/10.2210/pdb1ZVM/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Pichia
- Mutation(s): Yes
- Deposited: 2005-06-02 Released: 2006-06-06
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.270 (Depositor), 0.280 (DCC)
- R-Value Work: 0.228 (Depositor), 0.240 (DCC)
- R-Value Observed: 0.228 (Depositor)
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| ADP-ribosyl cyclase 1 | 256 | Homo sapiens | Mutation(s): 4 Gene Names: CD38 EC: 3.2.2.5 (PDB Primary Data), 3.2.2 (UniProt), 3.2.2.6 (UniProt), 2.4.99.20 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P28907 (Homo sapiens) Explore P28907 Go to UniProtKB: P28907 | |||||
PHAROS: P28907 GTEx: ENSG00000004468 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P28907 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | E [auth A] F [auth A] G [auth B] H [auth B] I [auth C] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.270 (Depositor), 0.280 (DCC)
- R-Value Work: 0.228 (Depositor), 0.240 (DCC)
- R-Value Observed: 0.228 (Depositor)
Space Group: P 2 2 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 114.439 | α = 90 |
| b = 115.704 | β = 90 |
| c = 98.441 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| SOLVE | phasing |
| CNS | refinement |
Entry History
Deposition Data
- Released Date: 2006-06-06 Deposition Author(s): Shi, W., Yang, T., Almo, S.C., Schramm, V.L., Sauve, A.
Revision History (Full details and data files)
- Version 1.0: 2006-06-06
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Derived calculations, Version format compliance - Version 1.3: 2021-10-20
Changes: Database references, Derived calculations - Version 1.4: 2024-10-30
Changes: Data collection, Structure summary
