Download MendeleyThe Crystal Structure of SRC from Biortus.
Wang, F., Cheng, W., Yuan, Z., Lin, D., Bao, C.To be published.
8XN8 | pdb_00008xn8
The Crystal Structure of SRC from Biortus.
- PDB DOI: https://doi.org/10.2210/pdb8XN8/pdb
- Classification: SIGNALING PROTEIN
- Organism(s): Mus musculus
- Expression System: Spodoptera frugiperda
- Mutation(s): No
- Deposited: 2023-12-29 Released: 2024-01-24
- Funding Organization(s): Not funded
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.95 Å
- R-Value Free: 0.224 (Depositor), 0.230 (DCC)
- R-Value Work: 0.185 (Depositor), 0.190 (DCC)
Starting Model: experimental
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This is version 1.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Proto-oncogene tyrosine-protein kinase Src | 451 | Mus musculus | Mutation(s): 0 Gene Names: Src EC: 2.7.10.2 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P05480 (Mus musculus) Explore P05480 Go to UniProtKB: P05480 | |||||
IMPC: MGI:98397 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P05480 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ADP (Subject of Investigation/LOI) Query on ADP | B [auth A] | ADENOSINE-5'-DIPHOSPHATE C10 H15 N5 O10 P2 XTWYTFMLZFPYCI-KQYNXXCUSA-N |  | ||
| GOL (Subject of Investigation/LOI) Query on GOL | D [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| EDO (Subject of Investigation/LOI) Query on EDO | E [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| MG (Subject of Investigation/LOI) Query on MG | C [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| PTR Query on PTR | A | L-PEPTIDE LINKING | C9 H12 N O6 P |  | TYR |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.95 Å
- R-Value Free: 0.224 (Depositor), 0.230 (DCC)
- R-Value Work: 0.185 (Depositor), 0.190 (DCC)
Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 51.204 | α = 90 |
| b = 87.468 | β = 90 |
| c = 105.802 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| Not funded | -- |
Revision History (Full details and data files)
- Version 1.0: 2024-01-24
Type: Initial release - Version 1.1: 2024-11-13
Changes: Structure summary
