9E8W | pdb_00009e8w

Deposited: 2024-11-06 Released: 2025-11-12
Deposition Author(s): Lu, J., Sawaya, M.R., Ge, P., Boyer, D.R., Eisenberg, D.S.
Funding Organization(s): National Institutes of Health/National Institute on Aging (NIH/NIA)

Experimental Data Snapshot

wwPDB Validation 3D Report Full Report

This is version 1.0 of the entry. See complete history.

Literature

Macromolecule Content

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Alpha-synuclein	A, B, C, D, E A, B, C, D, E, F, G, H, I, J	140	Homo sapiens	Mutation(s): 0
UniProt & NIH Common Fund Data Resources
Find proteins for P37840 (Homo sapiens) Explore P37840 Go to UniProtKB: P37840
PHAROS: P37840 GTEx: ENSG00000145335
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P37840
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 1 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
A1BGB (Subject of Investigation/LOI) Query on A1BGB Download Ideal Coordinates CCD File SDF format, chain K [auth A] SDF format, chain L [auth C] SDF format, chain M [auth E] SDF format, chain N [auth I] SDF format, chain O [auth I] MOL2 format, chain K [auth A] MOL2 format, chain L [auth C] MOL2 format, chain M [auth E] MOL2 format, chain N [auth I] MOL2 format, chain O [auth I] mmCIF format, chain K [auth A] mmCIF format, chain L [auth C] mmCIF format, chain M [auth E] mmCIF format, chain N [auth I] mmCIF format, chain O [auth I]	K [auth A], L [auth C], M [auth E], N [auth I], O [auth I]	2-(4-benzyl-1-oxophthalazin-2(1H)-yl)-N-(2,6-dimethylphenyl)acetamide C₂₅ H₂₃ N₃ O₂ ORLWGDAKUUGLJW-UHFFFAOYSA-N		Interactions Focus chain K [auth A] Focus chain L [auth C] Focus chain M [auth E] Focus chain N [auth I] Focus chain O [auth I] Interactions & Density Focus chain K [auth A] Focus chain L [auth C] Focus chain M [auth E] Focus chain N [auth I] Focus chain O [auth I]

Experimental Data & Validation

EM Software:

Task	Software Package	Version
MODEL REFINEMENT	PHENIX

Entry History & Funding Information

Deposition Author(s):

Lu, J.

Funding Organization	Location	Grant Number
National Institutes of Health/National Institute on Aging (NIH/NIA)	United States	1R01 AG07895
National Institutes of Health/National Institute on Aging (NIH/NIA)	United States	RF1 AG065407