Download MendeleyPB2 cap-binding domain of human pathogenic influenza A virus H5N1 in complex with m7GTP
Falke, S., Lewe, P., Witt, S., Wrenger, C., Meents, A.To be published.
9I2O | pdb_00009i2o
PB2 cap-binding domain of human pathogenic influenza A virus H5N1 in complex with m7GTP
- PDB DOI: https://doi.org/10.2210/pdb9I2O/pdb
- Classification: RNA BINDING PROTEIN
- Organism(s): Influenza A virus
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2025-01-21 Released: 2025-01-29
- Funding Organization(s): Helmholtz Association, German Federal Ministry for Education and Research
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.72 Å
- R-Value Free: 0.206 (Depositor), 0.206 (DCC)
- R-Value Work: 0.182 (Depositor), 0.183 (DCC)
- R-Value Observed: 0.185 (Depositor)
Starting Model: experimental
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This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Polymerase basic protein 2 | 188 | Influenza A virus | Mutation(s): 0 Gene Names: PB2 |  | |
UniProt | |||||
Find proteins for Q6DNL8 (Influenza A virus (strain A/Chicken/Hong Kong/YU22/2002 H5N1 genotype Z)) Explore Q6DNL8 Go to UniProtKB: Q6DNL8 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q6DNL8 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| MGT (Subject of Investigation/LOI) Query on MGT | B [auth A] | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE C11 H20 N5 O14 P3 BUJQMJUTTBGELS-KQYNXXCUSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.72 Å
- R-Value Free: 0.206 (Depositor), 0.206 (DCC)
- R-Value Work: 0.182 (Depositor), 0.183 (DCC)
- R-Value Observed: 0.185 (Depositor)
Space Group: P 65
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 81.75 | α = 90 |
| b = 81.75 | β = 90 |
| c = 55.009 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| PHENIX | phasing |
| XSCALE | data scaling |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-01-29 Deposition Author(s): Falke, S., Lewe, P., Witt, S., Wrenger, C., Meents, A.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Helmholtz Association | Germany | -- |
| German Federal Ministry for Education and Research | Germany | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-01-29
Type: Initial release
