Download MendeleyCryo-EM structure of the vault from human brain reveals symmetry mismatch at its caps
Lovestam, S.L., Scheres, S.H.W.To be published.
9R86 | pdb_00009r86
Major Vault Protein from Human Brain
- PDB DOI: https://doi.org/10.2210/pdb9R86/pdb
- EM Map EMD-53805: EMDB EMDataResource
- Classification: STRUCTURAL PROTEIN
- Organism(s): Homo sapiens
- Mutation(s): No
- Deposited: 2025-05-15 Released: 2025-07-02
- Funding Organization(s): Medical Research Council (MRC, United Kingdom)
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 3.10 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Major vault protein | A [auth A0], AA [auth At], B [auth A1], BA [auth Au], C [auth A2], CA [auth Av], D [auth A3], DA [auth Aw], E [auth A4], EA [auth Ax], F [auth A5], FA [auth Ay], G [auth A6], GA [auth Az], H [auth A7], HA [auth BA], I [auth A8], IA [auth BB], J [auth A9], JA [auth BC], K [auth Ac], KA [auth BD], L [auth Ad], LA [auth BE], M [auth Ae], MA [auth BF], N [auth Af], O [auth Ag], P [auth Ah], Q [auth Ai], R [auth Aj], S [auth Ak], T [auth Al], U [auth Am], V [auth An], W [auth Ap], X [auth Aq], Y [auth Ar], Z [auth As] | 893 | Homo sapiens | Mutation(s): 0 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q14764 (Homo sapiens) Explore Q14764 Go to UniProtKB: Q14764 | |||||
PHAROS: Q14764 GTEx: ENSG00000013364 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q14764 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 3.10 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
Entry History & Funding Information
Deposition Data
- Released Date: 2025-07-02 Deposition Author(s): Lovestam, S.L., Scheres, S.H.W.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Medical Research Council (MRC, United Kingdom) | United Kingdom | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-07-02
Type: Initial release
