Annotations: 1WFD

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1wfda1	All alpha proteins	Spectrin repeat-like	MIT domain	MIT domain	Hypothetical protein 1500032H18Rik	house mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)
A	d1wfda3	Artifacts	Tags	Tags	Tags	C-terminal Tags	house mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)
A	d1wfda2	Artifacts	Tags	Tags	Tags	N-terminal Tags	house mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	MIT domain	8031107	4002917	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	MIT domain	8043485	3001898	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MIT	e1wfdA1	A: alpha bundles	X: Spectrin repeat-like	H: MIT domain (From Topology)	T: MIT domain	F: MIT	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.58.80	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF04212	MIT (microtubule interacting and transport) domain (MIT)	MIT (microtubule interacting and transport) domain	The MIT domain forms an asymmetric three-helix bundle [3] and binds ESCRT-III (endosomal sorting complexes required for transport) substrates [2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Hypothetical protein 1500032H18	binding phospholipid binding lipid binding phosphatidylinositol binding protein binding protein domain specific binding identical protein binding	membrane organization cytoskeleton-dependent cytokinesis mitotic cytokinetic process mitotic cytokinesis cytokinesis mitotic cell cycle cellular component organization mitotic cell cycle process midbody abscission cytokinetic process cellular process cellular component organization or biogenesis cell cycle cell division membrane organization cytoskeleton-dependent cytokinesis mitotic cytokinetic process mitotic cytokinesis cytokinesis mitotic cell cycle cellular component organization mitotic cell cycle process midbody abscission cytokinetic process cellular process cellular component organization or biogenesis cell cycle cell division cell cycle process	midbody cellular anatomical structure membrane-bounded organelle endosome membrane intracellular anatomical structure endosome membrane intracellular vesicle late endosome membrane intracellular membrane-bounded organelle endomembrane system intracellular organelle cytoplasmic vesicle membrane bounding membrane of organelle midbody cellular anatomical structure membrane-bounded organelle endosome membrane intracellular anatomical structure endosome membrane intracellular vesicle late endosome membrane intracellular membrane-bounded organelle endomembrane system intracellular organelle cytoplasmic vesicle membrane bounding membrane of organelle cytoplasmic vesicle vesicle membrane organelle late endosome cytoplasm vesicle organelle membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR007330	MIT domain	Domain
A	IPR032341	MITD1, C-terminal phospholipase D-like domain	Domain
A	IPR036181	MIT domain superfamily	Homologous Superfamily
A	IPR038113	MITD1, C-terminal phospholipase D-like domain superfamily	Homologous Superfamily
A	IPR045331	MITD1, N-terminal domain	Domain
A	IPR052817	MIT domain-containing protein 1	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.