2WVA | pdb_00002wva

Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2wvaa2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
A	d2wvaa1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
B	d2wvab2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
B	d2wvab1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
C [auth E]	d2wvae2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
C [auth E]	d2wvae1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
D [auth F]	d2wvaf2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
D [auth F]	d2wvaf1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
E [auth V]	d2wvav2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
E [auth V]	d2wvav1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
F [auth X]	d2wvax2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
F [auth X]	d2wvax1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
G [auth Y]	d2wvay2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
G [auth Y]	d2wvay1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
H [auth Z]	d2wvaz2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)
H [auth Z]	d2wvaz1	Alpha and beta proteins (a/b)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	automated matches	automated matches	(Zymomonas mobilis ) [TaxId: 542 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)
D [auth F]	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
D [auth F]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
D [auth F]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)
E [auth V]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)
E [auth V]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
E [auth V]	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
F [auth X]	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
F [auth X]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
F [auth X]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)
G [auth Y]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
G [auth Y]	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
G [auth Y]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)
H [auth Z]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044269	3001790	SCOP2B (2022-06-29)
H [auth Z]	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044249	3001728	SCOP2B (2022-06-29)
H [auth Z]	SCOP2B Superfamily	Thiamin diphosphate-binding fold (THDP-binding)	8044268	3001790	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	TPP_enzyme_M	e2wvaA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
A	TPP_enzyme_C	e2wvaA3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
A	TPP_enzyme_N	e2wvaA2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)
B	TPP_enzyme_M	e2wvaB1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
B	TPP_enzyme_C	e2wvaB3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
B	TPP_enzyme_N	e2wvaB2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)
C [auth E]	TPP_enzyme_M	e2wvaE1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
C [auth E]	TPP_enzyme_C	e2wvaE3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
C [auth E]	TPP_enzyme_N	e2wvaE2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)
D [auth F]	TPP_enzyme_M	e2wvaF1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
D [auth F]	TPP_enzyme_C	e2wvaF3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
D [auth F]	TPP_enzyme_N	e2wvaF2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)
E [auth V]	TPP_enzyme_M	e2wvaV1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
E [auth V]	TPP_enzyme_C	e2wvaV3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
E [auth V]	TPP_enzyme_N	e2wvaV2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)
F [auth X]	TPP_enzyme_M	e2wvaX1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
F [auth X]	TPP_enzyme_C	e2wvaX3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
F [auth X]	TPP_enzyme_N	e2wvaX2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)
G [auth Y]	TPP_enzyme_M	e2wvaY1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
G [auth Y]	TPP_enzyme_C	e2wvaY3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
G [auth Y]	TPP_enzyme_N	e2wvaY2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)
H [auth Z]	TPP_enzyme_M	e2wvaZ1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: TPP_enzyme_M	ECOD (1.6)
H [auth Z]	TPP_enzyme_C	e2wvaZ3	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_C	ECOD (1.6)
H [auth Z]	TPP_enzyme_N	e2wvaZ2	A: a/b three-layered sandwiches	X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)	T: Thiamin diphosphate-binding fold (THDP-binding)	F: TPP_enzyme_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
A	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
B	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
B	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
C [auth E]	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
C [auth E]	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
D [auth F]	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
D [auth F]	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
E [auth V]	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
E [auth V]	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
F [auth X]	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
F [auth X]	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
G [auth Y]	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
G [auth Y]	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
H [auth Z]	3.40.50.970	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	CATH (4.3.0)
H [auth Z]	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	PF00205	Thiamine pyrophosphate enzyme, central domain (TPP_enzyme_M)	Thiamine pyrophosphate enzyme, central domain	The central domain of TPP enzymes contains a 2-fold Rossman fold.	Domain
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain (TPP_enzyme_C)	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain		Domain
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain (TPP_enzyme_N)	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	PYRUVATE DECARBOXYLASE	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding pyruvate decarboxylase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity vitamin binding thiamine pyrophosphate binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding pyruvate decarboxylase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity vitamin binding thiamine pyrophosphate binding anion binding quaternary ammonium group binding heterocyclic compound binding sulfur compound binding	catabolic process aromatic amino acid metabolic process oxoacid metabolic process small molecule biosynthetic process aromatic amino acid family catabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process alcohol metabolic process organic acid catabolic process organic acid metabolic process amino acid catabolic process via Ehrlich pathway aromatic amino acid family catabolic process to alcohol via Ehrlich pathway biosynthetic process carboxylic acid catabolic process catabolic process aromatic amino acid metabolic process oxoacid metabolic process small molecule biosynthetic process aromatic amino acid family catabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process alcohol metabolic process organic acid catabolic process organic acid metabolic process amino acid catabolic process via Ehrlich pathway aromatic amino acid family catabolic process to alcohol via Ehrlich pathway biosynthetic process carboxylic acid catabolic process amino acid catabolic process to alcohol via Ehrlich pathway alcohol biosynthetic process small molecule metabolic process metabolic process cellular process small molecule catabolic process amino acid catabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR012001	Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain	Domain
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR000399	TPP-binding enzyme, conserved site	Conserved Site
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR047214	Pyruvate decarboxylase/indolepyruvate decarboxylase-like, PP-binding domain	Domain
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR012000	Thiamine pyrophosphate enzyme, central domain	Domain
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR029061	Thiamin diphosphate-binding fold	Homologous Superfamily
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR012110	Pyruvate decarboxylase/indolepyruvate decarboxylase-like	Family
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR047213	Pyruvate decarboxylase/indolepyruvate decarboxylase-like, pyrimidine-binding domain	Domain
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR029035	DHS-like NAD/FAD-binding domain superfamily	Homologous Superfamily
A, B, C [auth E], D [auth F], E [auth V], A, B, C [auth E], D [auth F], E [auth V], F [auth X], G [auth Y], H [auth Z]	IPR011766	Thiamine pyrophosphate enzyme, TPP-binding	Domain

Prepare Data

Validate Data

Deposit Data

Help and Resources

.id_divider{ color: #ccc; padding: 0 10px 0 10px; } .extended_id_info{ color: #ccc; font-size: 18px; position: relative; top: -10px; left: 4px; } 2WVA | pdb_00002wva

Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Domain Annotation: ECOD Classification ECOD Database Homepage

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage

2WVA | pdb_00002wva