3FGT | pdb_00003fgt

Two chain form of the 66.3 kDa protein from mouse lacking the linker peptide

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Class II glutamine amidotransferases	8103582	3000131	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Class II glutamine amidotransferases	8103582	3000131	SCOP2B (2022-06-29)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.60.60.20	Alpha Beta	4-Layer Sandwich	Penicillin V Acylase	Chain A	CATH (4.3.0)
A	2.10.70.60	Mainly Beta	Ribbon	Complement Module	domain 1	CATH (4.3.0)
A	1.10.439.20	Mainly Alpha	Orthogonal Bundle	Penicillin Amidohydrolase	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B	PF04916	Phospholipase B (Phospholip_B)	Phospholipase B	-	Family
A	PF04916	Phospholipase B (Phospholip_B)	Phospholipase B	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B	Putative phospholipase B-like 2 40 kDa form	hydrolase activity, acting on ester bonds hydrolase activity catalytic activity phospholipase activity lipase activity	lipid catabolic process catabolic process metabolic process cellular process primary metabolic process lipid metabolic process	membrane-bounded organelle intracellular anatomical structure membrane-enclosed lumen lytic vacuole vacuolar lumen vacuole intracellular membrane-bounded organelle lysosomal lumen intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle cytoplasm membrane-bounded organelle intracellular anatomical structure membrane-enclosed lumen lytic vacuole vacuolar lumen vacuole intracellular membrane-bounded organelle lysosomal lumen intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle cytoplasm lysosome
A	Putative phospholipase B-like 2 28 kDa form	hydrolase activity, acting on ester bonds hydrolase activity catalytic activity phospholipase activity lipase activity	lipid catabolic process catabolic process metabolic process cellular process primary metabolic process lipid metabolic process	membrane-bounded organelle intracellular anatomical structure membrane-enclosed lumen lytic vacuole vacuolar lumen vacuole intracellular membrane-bounded organelle lysosomal lumen intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle cytoplasm membrane-bounded organelle intracellular anatomical structure membrane-enclosed lumen lytic vacuole vacuolar lumen vacuole intracellular membrane-bounded organelle lysosomal lumen intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle cytoplasm lysosome

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B	IPR043042	Phospholipase B-like, domain 3	Homologous Superfamily
B	IPR043041	Phospholipase B-like, domain 2	Homologous Superfamily
B	IPR043040	Phospholipase B-like, domain 1	Homologous Superfamily
B	IPR007000	Phospholipase B-like	Family
A	IPR043042	Phospholipase B-like, domain 3	Homologous Superfamily
A	IPR043041	Phospholipase B-like, domain 2	Homologous Superfamily
A	IPR043040	Phospholipase B-like, domain 1	Homologous Superfamily
A	IPR007000	Phospholipase B-like	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
B	OCS	Parent Component: CYS RESID: AA0556 PSI-MOD : L-cysteic acid (L-cysteine sulfonic acid) MOD:00460

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.