3LUR | pdb_00003lur

Crystal structure of Putative bacterial transcription regulation protein (NP_372959.1) from Staphylococcus aureus MU50 at 1.81 A resolution

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ACass2e3lurA1 A: a+b duplicates or obligate multimersX: Probable bacterial effector-binding domain (From Topology)H: Probable bacterial effector-binding domain (From Topology)T: Probable bacterial effector-binding domainF: Cass2ECOD (1.6)
BCass2e3lurB1 A: a+b duplicates or obligate multimersX: Probable bacterial effector-binding domain (From Topology)H: Probable bacterial effector-binding domain (From Topology)T: Probable bacterial effector-binding domainF: Cass2ECOD (1.6)
CCass2e3lurC1 A: a+b duplicates or obligate multimersX: Probable bacterial effector-binding domain (From Topology)H: Probable bacterial effector-binding domain (From Topology)T: Probable bacterial effector-binding domainF: Cass2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr Chain ACATH (4.3.0)
B3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr Chain ACATH (4.3.0)
C3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr Chain ACATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF14526Integron-associated effector binding protein (Cass2)Integron-associated effector binding proteinThis family contains Cass2 from Vibrio cholerae, an integron-associated protein that has been shown [1] to bind cationic drug compounds with submicromolar affinity. Cass2 has been proposed to be representative of a larger family of independent effect ...This family contains Cass2 from Vibrio cholerae, an integron-associated protein that has been shown [1] to bind cationic drug compounds with submicromolar affinity. Cass2 has been proposed to be representative of a larger family of independent effector-binding proteins associated with lateral gene transfer within Vibrio and other closely-related species.
Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C
IPR010499Bacterial transcription activator, effector bindingDomain
A, B, C
IPR029441Integron-associated effector binding proteinDomain
A, B, C
IPR053182Putative transcriptional regulator YobU-likeFamily
A, B, C
IPR011256Regulatory factor, effector binding domain superfamilyHomologous Superfamily