Open CtIDH. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
| Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| D | d4aoyd_ | Alpha and beta proteins (a/b) | Isocitrate/Isopropylmalate dehydrogenase-like | Isocitrate/Isopropylmalate dehydrogenase-like | automated matches | automated matches | (Acetivibrio thermocellus ) [TaxId: 1515 ], | SCOPe (2.08) |
| C | d4aoyc_ | Alpha and beta proteins (a/b) | Isocitrate/Isopropylmalate dehydrogenase-like | Isocitrate/Isopropylmalate dehydrogenase-like | automated matches | automated matches | (Acetivibrio thermocellus ) [TaxId: 1515 ], | SCOPe (2.08) |
| B | d4aoyb_ | Alpha and beta proteins (a/b) | Isocitrate/Isopropylmalate dehydrogenase-like | Isocitrate/Isopropylmalate dehydrogenase-like | automated matches | automated matches | (Acetivibrio thermocellus ) [TaxId: 1515 ], | SCOPe (2.08) |
| A | d4aoya_ | Alpha and beta proteins (a/b) | Isocitrate/Isopropylmalate dehydrogenase-like | Isocitrate/Isopropylmalate dehydrogenase-like | automated matches | automated matches | (Acetivibrio thermocellus ) [TaxId: 1515 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| D | Iso_dh | e4aoyD1 | A: a/b three-layered sandwiches | X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | T: Isocitrate/Isopropylmalate dehydrogenase-like | F: Iso_dh | ECOD (1.6) |
| C | Iso_dh | e4aoyC2 | A: a/b three-layered sandwiches | X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | T: Isocitrate/Isopropylmalate dehydrogenase-like | F: Iso_dh | ECOD (1.6) |
| B | Iso_dh | e4aoyB2 | A: a/b three-layered sandwiches | X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | T: Isocitrate/Isopropylmalate dehydrogenase-like | F: Iso_dh | ECOD (1.6) |
| A | Iso_dh | e4aoyA1 | A: a/b three-layered sandwiches | X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology) | T: Isocitrate/Isopropylmalate dehydrogenase-like | F: Iso_dh | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
| Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
|---|---|---|---|---|---|---|
| D | 3.40.718.10 | Alpha Beta | 3-Layer(aba) Sandwich | Isopropylmalate Dehydrogenase | Isopropylmalate Dehydrogenase | CATH (4.3.0) |
| C | 3.40.718.10 | Alpha Beta | 3-Layer(aba) Sandwich | Isopropylmalate Dehydrogenase | Isopropylmalate Dehydrogenase | CATH (4.3.0) |
| B | 3.40.718.10 | Alpha Beta | 3-Layer(aba) Sandwich | Isopropylmalate Dehydrogenase | Isopropylmalate Dehydrogenase | CATH (4.3.0) |
| A | 3.40.718.10 | Alpha Beta | 3-Layer(aba) Sandwich | Isopropylmalate Dehydrogenase | Isopropylmalate Dehydrogenase | CATH (4.3.0) |
