4V12 | pdb_00004v12

Crystal structure of the MSMEG_6754 dehydratase from Mycobacterium smegmatis


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AMaoC_dehydratase4v12A1 A: a+b two layersX: Thioesterase/thiol ester dehydrase-isomerase-likeH: Thioesterase/thiol ester dehydrase-isomerase (From Topology)T: Thioesterase/thiol ester dehydrase-isomeraseF: MaoC_dehydratasECOD (1.6)
AMaoC_dehydrat_Ne4v12A2 A: a+b two layersX: Thioesterase/thiol ester dehydrase-isomerase-likeH: Thioesterase/thiol ester dehydrase-isomerase (From Topology)T: Thioesterase/thiol ester dehydrase-isomeraseF: MaoC_dehydrat_NECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF13452FAS1-like, dehydratase domain region (FAS1_DH_region)FAS1-like, dehydratase domain regionThis is a region of the dehydratase domain found in Fatty acid synthase subunit beta from Saccharomyces cerevisiae (FAS1, [1]) and similar sequences mainly found in eukaryotes and bacteria. FAS1 catalyses the formation of long-chain fatty acids from ...This is a region of the dehydratase domain found in Fatty acid synthase subunit beta from Saccharomyces cerevisiae (FAS1, [1]) and similar sequences mainly found in eukaryotes and bacteria. FAS1 catalyses the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This entry is often found associated with Pfam:PF01575.
Domain
PF01575MaoC like domain (MaoC_dehydratas)MaoC like domainThe maoC gene is part of a operon with maoA which is involved in the synthesis of monoamine oxidase [1]. The MaoC protein is found to share similarity with a wide variety of enzymes; estradiol 17 beta-dehydrogenase 4, peroxisomal hydratase-dehydroge ...The maoC gene is part of a operon with maoA which is involved in the synthesis of monoamine oxidase [1]. The MaoC protein is found to share similarity with a wide variety of enzymes; estradiol 17 beta-dehydrogenase 4, peroxisomal hydratase-dehydrogenase-epimerase, fatty acid synthase beta subunit. Several bacterial proteins that are composed solely of this domain have (R)-specific enoyl-CoA hydratase activity [2]. This domain is also present in the NodN nodulation protein N.
Domain

InterPro: Protein Family Classification InterPro Database Homepage