Annotations: 5JAI

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Enoyl_reductase	e5jaiA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NAD(P)-binding Rossmann-fold domains	F: Enoyl_reductase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.720	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	NAD(P)-binding Rossmann-like Domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF07055	Enoyl reductase FAD binding domain (Eno-Rase_FAD_bd)	Enoyl reductase FAD binding domain	-	Family
A	PF12242	NAD(P)H binding domain of trans-2-enoyl-CoA reductase (Eno-Rase_NADH_b)	NAD(P)H binding domain of trans-2-enoyl-CoA reductase	-	Family
A	PF12241	Trans-2-enoyl-CoA reductase catalytic region (Enoyl_reductase)	Trans-2-enoyl-CoA reductase catalytic region	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Enoyl-[acyl-carrier-protein] reductase [NADH]	oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor trans-2-enoyl-CoA reductase (NADH) activity oxidoreductase activity, acting on the CH-CH group of donors catalytic activity NAD binding binding nucleoside phosphate binding purine nucleotide binding adenyl nucleotide binding nucleotide binding heterocyclic compound binding small molecule binding enoyl-[acyl-carrier-protein] reductase (NADH) activity oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor trans-2-enoyl-CoA reductase (NADH) activity oxidoreductase activity, acting on the CH-CH group of donors catalytic activity NAD binding binding nucleoside phosphate binding purine nucleotide binding adenyl nucleotide binding nucleotide binding heterocyclic compound binding small molecule binding enoyl-[acyl-carrier-protein] reductase (NADH) activity enoyl-[acyl-carrier-protein] reductase [NAD(P)H] activity	fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process lipid biosynthetic process primary metabolic process organic acid biosynthetic process organic acid metabolic process fatty acid biosynthetic process carboxylic acid biosynthetic process biosynthetic process small molecule metabolic process metabolic process fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process lipid biosynthetic process primary metabolic process organic acid biosynthetic process organic acid metabolic process fatty acid biosynthetic process carboxylic acid biosynthetic process biosynthetic process small molecule metabolic process metabolic process cellular process monocarboxylic acid metabolic process lipid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR024910	Trans-2-enoyl-CoA reductase catalytic domain, putative	Domain
A	IPR050048	Trans-2-enoyl-CoA reductase-like, NAD(P)H binding domain	Domain
A	IPR010758	Trans-2-enoyl-CoA reductase	Family
A	IPR024906	Enoyl reductase FAD binding domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.