6A36 | pdb_00006a36

Mandelate oxidase mutant-Y128F with the 3-fluoropyruvic acid FMN adduct

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6a36a_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	FMN-linked oxidoreductases	automated matches	automated matches	Nocardia orientalis (Amycolatopsis orientalis ) [TaxId: 31958 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	IMPDH_1st_1	e6a36A1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: IMPDH_1st_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01070	FMN-dependent dehydrogenase (FMN_dh)	FMN-dependent dehydrogenase		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	4-hydroxymandelate oxidase	FMN binding binding nucleoside phosphate binding ion binding anion binding nucleotide binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor oxidoreductase activity oxidoreductase activity, acting on CH-OH group of donors catalytic activity	carbohydrate derivative biosynthetic process peptide antibiotic metabolic process carbohydrate derivative metabolic process amide biosynthetic process vancomycin metabolic process antibiotic biosynthetic process antibiotic metabolic process peptide antibiotic biosynthetic process peptide biosynthetic process biosynthetic process vancomycin biosynthetic process metabolic process cellular process amide metabolic process carbohydrate derivative biosynthetic process peptide antibiotic metabolic process carbohydrate derivative metabolic process amide biosynthetic process vancomycin metabolic process antibiotic biosynthetic process antibiotic metabolic process peptide antibiotic biosynthetic process peptide biosynthetic process biosynthetic process vancomycin biosynthetic process metabolic process cellular process amide metabolic process nonribosomal peptide biosynthetic process peptide metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR012133	Alpha-hydroxy acid dehydrogenase, FMN-dependent	Family
A	IPR008259	FMN-dependent alpha-hydroxy acid dehydrogenase, active site	Active Site
A	IPR013785	Aldolase-type TIM barrel	Homologous Superfamily
A	IPR037396	FMN hydroxy acid dehydrogenase domain	Domain
A	IPR000262	FMN-dependent dehydrogenase	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.