6CD8 | pdb_00006cd8

Complex of GID4 fragment with short peptide

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UNK_F_TYPE	e6cd8A1	A: beta barrels	X: Lipocalins/Streptavidin	H: Avidin/Streptavidin (From Topology)	T: Avidin/Streptavidin	F: UNK_F_TYPE	ECOD (1.6)
B	UNK_F_TYPE	e6cd8B1	A: beta barrels	X: Lipocalins/Streptavidin	H: Avidin/Streptavidin (From Topology)	T: Avidin/Streptavidin	F: UNK_F_TYPE	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF09783	Vacuolar import and degradation protein (Vac_ImportDeg)	Vacuolar import and degradation protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Glucose-induced degradation protein 4 homolog	aminoacyltransferase activity ubiquitin-like protein transferase activity catalytic activity, acting on a protein acyltransferase activity ubiquitin-like protein ligase activity ubiquitin protein ligase activity transferase activity catalytic activity ubiquitin-protein transferase activity	catabolic process proteolysis involved in protein catabolic process primary metabolic process proteasomal protein catabolic process protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process macromolecule catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process proteolysis ubiquitin-dependent protein catabolic process metabolic process cellular process macromolecule metabolic process catabolic process proteolysis involved in protein catabolic process primary metabolic process proteasomal protein catabolic process protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process macromolecule catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process proteolysis ubiquitin-dependent protein catabolic process metabolic process cellular process macromolecule metabolic process protein metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex ubiquitin ligase complex catalytic complex transferase complex intracellular protein-containing complex
C, D	Tetrapeptide PSRV	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR018618	GID complex substrate-recognition subunit 4/10-like	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B	Pharos: Q8IVV7	atypical teratoid rhabdoid tumor glioblastoma lung cancer pancreatic intraductal papillary-mucinous neoplasm autism spectrum disorder invasive ductal breast carcinoma myocardial infarction skin basal cell carcinoma ductal breast carcinoma in situ large cell medulloblastoma ovarian cancer spina bifida

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.