Annotations: 8IS0

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00266	Aminotransferase class-V (Aminotran_5)	Aminotransferase class-V	This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Probable hercynylcysteine sulfoxide lyase	carbon-sulfur lyase activity lyase activity hercynylcysteine sulfoxide lyase activity (ergothioneine-forming) catalytic activity	ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide amino-acid betaine biosynthetic process oxoacid metabolic process sulfur amino acid metabolic process modified amino acid biosynthetic process organic acid metabolic process organic acid biosynthetic process ergothioneine metabolic process carboxylic acid biosynthetic process modified histidine biosynthetic process sulfur compound metabolic process small molecule metabolic process small molecule biosynthetic process carboxylic acid metabolic process ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide amino-acid betaine biosynthetic process oxoacid metabolic process sulfur amino acid metabolic process modified amino acid biosynthetic process organic acid metabolic process organic acid biosynthetic process ergothioneine metabolic process carboxylic acid biosynthetic process modified histidine biosynthetic process sulfur compound metabolic process small molecule metabolic process small molecule biosynthetic process carboxylic acid metabolic process modified amino acid metabolic process amino-acid betaine metabolic process sulfur compound biosynthetic process biosynthetic process ergothioneine biosynthetic process metabolic process cellular process modified histidine metabolic process sulfur amino acid biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR015424	Pyridoxal phosphate-dependent transferase	Homologous Superfamily
A, B	IPR015421	Pyridoxal phosphate-dependent transferase, major domain	Homologous Superfamily
A, B	IPR015422	Pyridoxal phosphate-dependent transferase, small domain	Homologous Superfamily
A, B	IPR000192	Aminotransferase class V domain	Domain
A, B	IPR027563	Pyridoxal-phosphate-dependent protein EgtE	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.