8SMF | pdb_00008smf

Structure of SPO1 phage Tad2 in complex with 1''-3' gcADPR


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF11195Thoeris anti-defense 2-like domain (Tad2-like)Thoeris anti-defense 2-like domainThis entry represents Thoeris anti-defense 2 from Bacillus phage SP01 (Tad2) and similar sequences from tailed bacteriophages and bacterial prophages. Tad2 is an anti-defence protein that counteracts the host Thoeris antiviral defence system. It sequ ...This entry represents Thoeris anti-defense 2 from Bacillus phage SP01 (Tad2) and similar sequences from tailed bacteriophages and bacterial prophages. Tad2 is an anti-defence protein that counteracts the host Thoeris antiviral defence system. It sequesters the immune signalling molecules produced by Thoeris TIR-domain proteins in response to phage infection [1]. This entry also includes AcrIIA7 Cas9 inhibitor protein gene.
Domain