9A0C | pdb_00009a0c

Refined structure of MR78 Antibody in complex with Marburg glycoprotein using Rosetta

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
M	Marburg Glycoprotein 1	-	viral process fusion of virus membrane with host endosome membrane membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms adhesion of symbiont to host cell viral life cycle adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction symbiont entry into host cell symbiont entry into host	virion component viral membrane viral envelope cellular anatomical structure membrane host cell plasma membrane host cellular component host cell part host cell membrane other organism part virion membrane
P	MR78 antibody light chain	-	-	-
O	MR78 antobody heavy chain	-	response to stimulus immune response immune system process adaptive immune response	cell periphery cellular anatomical structure plasma membrane membrane protein-containing complex immunoglobulin complex extracellular region
N	Marburg Glycoprotein 2	-	viral process fusion of virus membrane with host endosome membrane membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms adhesion of symbiont to host cell viral life cycle adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction symbiont entry into host cell symbiont entry into host	virion component viral membrane viral envelope cellular anatomical structure membrane host cell plasma membrane host cellular component host cell part host cell membrane other organism part virion membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
M	IPR018154	TLV/ENV coat polyprotein	Family
M	IPR014625	Filoviruses glycoprotein	Family
M	IPR002561	Filoviruses glycoprotein, extracellular domain	Domain
M	IPR054584	Envelope glycoprotein GP2-like, HR1-HR2	Domain
O	IPR050150	Immunoglobulin Variable Light Chain	Family
O	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
O	IPR036179	Immunoglobulin-like domain superfamily	Homologous Superfamily
O	IPR013106	Immunoglobulin V-set domain	Domain
O	IPR003599	Immunoglobulin domain subtype	Domain
O	IPR007110	Immunoglobulin-like domain	Domain
N	IPR018154	TLV/ENV coat polyprotein	Family
N	IPR014625	Filoviruses glycoprotein	Family
N	IPR002561	Filoviruses glycoprotein, extracellular domain	Domain
N	IPR054584	Envelope glycoprotein GP2-like, HR1-HR2	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.