9M2A | pdb_00009m2a

The crystal structure of the trypanosome alternative oxidase complexed with a trypanocidal phosphonium derivative (compound1)


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF01786Alternative oxidase (AOX)Alternative oxidaseThe alternative oxidase is used as a second terminal oxidase in the mitochondria, electrons are transfered directly from reduced ubiquinol to oxygen forming water [2]. This is not coupled to ATP synthesis and is not inhibited by cyanide, this pathwa ...The alternative oxidase is used as a second terminal oxidase in the mitochondria, electrons are transfered directly from reduced ubiquinol to oxygen forming water [2]. This is not coupled to ATP synthesis and is not inhibited by cyanide, this pathway is a single step process [1]. In rice the transcript levels of the alternative oxidase are increased by low temperature [1].
Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D
IPR002680Alternative oxidaseFamily
A, B, C, D
IPR038659Alternative oxidase superfamilyHomologous Superfamily