Download MendeleyAPC with an inhibitor
Zhang, J., Yang, X.Y., Song, K.To be published.
5Z8H | pdb_00005z8h
APC with an inhibitor
- PDB DOI: https://doi.org/10.2210/pdb5Z8H/pdb
- Classification: PROTEIN BINDING/INHIBITOR
- Organism(s): Homo sapiens
- Expression System: Homo sapiens
- Mutation(s): No
- Deposited: 2018-01-31 Released: 2019-02-06
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.79 Å
- R-Value Free: 0.211 (Depositor), 0.220 (DCC)
- R-Value Work: 0.154 (Depositor), 0.170 (DCC)
- R-Value Observed: 0.157 (Depositor)
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Adenomatous polyposis coli protein | 339 | Homo sapiens | Mutation(s): 0 Gene Names: APC, DP2.5 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P25054 (Homo sapiens) Explore P25054 Go to UniProtKB: P25054 | |||||
PHAROS: P25054 GTEx: ENSG00000134982 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P25054 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Peptide inhibitor | 9 | Homo sapiens | Mutation(s): 0 |  | |
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GOL Query on GOL | C [auth A], D [auth A], E [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.79 Å
- R-Value Free: 0.211 (Depositor), 0.220 (DCC)
- R-Value Work: 0.154 (Depositor), 0.170 (DCC)
- R-Value Observed: 0.157 (Depositor)
Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 51.486 | α = 90 |
| b = 63.328 | β = 95.83 |
| c = 52.974 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| SCALEPACK | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2019-02-06 Deposition Author(s): Zhang, J., Yang, X.Y., Song, K.
Revision History (Full details and data files)
- Version 1.0: 2019-02-06
Type: Initial release - Version 1.1: 2024-10-23
Changes: Data collection, Database references, Structure summary
