8XND | pdb_00008xnd

Crystal structure of serine hydroxymethyltransferase 1


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.45 Å
  • R-Value Free: 
    0.192 (Depositor), 0.171 (DCC) 
  • R-Value Work: 
    0.153 (Depositor), 0.143 (DCC) 
  • R-Value Observed: 
    0.155 (Depositor) 

Starting Model: experimental
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Ligand Structure Quality Assessment 


This is version 1.0 of the entry. See complete history


Literature

Crystal structure of serine hydroxymethyltransferase 1

Fan, S.Wei, X.Lv, R.Wang, C.Tang, M.Jin, Y.Yang, Z.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Serine hydroxymethyltransferase, cytosolic
A, B, C, D
472Homo sapiensMutation(s): 0 
Gene Names: SHMT1
EC: 2.1.2.1
UniProt & NIH Common Fund Data Resources
Find proteins for P34896 (Homo sapiens)
Explore P34896 
Go to UniProtKB:  P34896
PHAROS:  P34896
GTEx:  ENSG00000176974 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP34896
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 3.45 Å
  • R-Value Free:  0.192 (Depositor), 0.171 (DCC) 
  • R-Value Work:  0.153 (Depositor), 0.143 (DCC) 
  • R-Value Observed: 0.155 (Depositor) 
Space Group: P 32
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 151.54α = 90
b = 151.54β = 90
c = 234.97γ = 120
Software Package:
Software NamePurpose
REFMACrefinement
XDSdata reduction
Aimlessdata scaling
PHASERphasing

Structure Validation

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Ligand Structure Quality Assessment 


Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
Other government2018YFA0901800

Revision History  (Full details and data files)

  • Version 1.0: 2025-04-02
    Type: Initial release