Download MendeleyNicotinic receptor subunit components and ligand molecular features underlying neonicoitinoid knockdown actions on the malaria vector mosquito Anopheles gambiae
Ihara, M., Matuda, K.To be published.
8XSW | pdb_00008xsw
Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Complexed with Dinotefuran
- PDB DOI: https://doi.org/10.2210/pdb8XSW/pdb
- Classification: SIGNALING PROTEIN
- Organism(s): Lymnaea stagnalis
- Expression System: Komagataella pastoris
- Mutation(s): Yes
- Deposited: 2024-01-10 Released: 2024-12-18
- Funding Organization(s): Japan Society for the Promotion of Science (JSPS)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.60 Å
- R-Value Free: 0.233 (Depositor), 0.227 (DCC)
- R-Value Work: 0.166 (Depositor), 0.171 (DCC)
Starting Model: experimental
View more details
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Acetylcholine-binding protein | 209 | Lymnaea stagnalis | Mutation(s): 1 |  | |
UniProt | |||||
Find proteins for P58154 (Lymnaea stagnalis) Explore P58154 Go to UniProtKB: P58154 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P58154 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| A1LW0 (Subject of Investigation/LOI) Query on A1LW0 | F [auth A], G [auth B], H [auth C], I [auth D], J [auth E] | 2-methyl-1-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine C7 H14 N4 O3 YKBZOVFACRVRJN-LURJTMIESA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.60 Å
- R-Value Free: 0.233 (Depositor), 0.227 (DCC)
- R-Value Work: 0.166 (Depositor), 0.171 (DCC)
Space Group: P 65
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 74.728 | α = 90 |
| b = 74.728 | β = 90 |
| c = 351.295 | γ = 120 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data reduction |
| Aimless | data scaling |
| PHASER | phasing |
| REFMAC | refinement |
Entry History & Funding Information
Deposition Data
- Released Date: 2024-12-18 Deposition Author(s): Ihara, M., Okajima, T., Yamashita, A., Matsuda, K.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Japan Society for the Promotion of Science (JSPS) | Japan | 16K21507 |
| Japan Society for the Promotion of Science (JSPS) | Japan | 22H02350 |
| Japan Society for the Promotion of Science (JSPS) | Japan | 21H04718 |
Revision History (Full details and data files)
- Version 1.0: 2024-12-18
Type: Initial release
