Download MendeleyHuman NAT16 encodes histidine alpha-acetyltransferase
Myllykoski, M., Osberg, C., Lundekvam, M., Arnesen, T.To be published.
9EMO | pdb_00009emo
Crystal structure of Histidine acetyltransferase with L-arginine and coenzyme A disulfide
- PDB DOI: https://doi.org/10.2210/pdb9EMO/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): No
- Deposited: 2024-03-09 Released: 2025-03-19
- Funding Organization(s): European Research Council (ERC)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.238 (Depositor), 0.242 (DCC)
- R-Value Work: 0.223 (Depositor), 0.223 (DCC)
- R-Value Observed: 0.223 (Depositor)
Starting Model: experimental
View more details
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Probable N-acetyltransferase 16 | 334 | Homo sapiens | Mutation(s): 0 Gene Names: NAT16, C7orf52 EC: 2.3.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8N8M0 (Homo sapiens) Explore Q8N8M0 Go to UniProtKB: Q8N8M0 | |||||
PHAROS: Q8N8M0 GTEx: ENSG00000167011 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8N8M0 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 5NG (Subject of Investigation/LOI) Query on 5NG | B [auth A] | [[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate C42 H70 N14 O32 P6 S2 YAISMNQCMHVVLO-BJLFRJKCSA-N |  | ||
| ARG (Subject of Investigation/LOI) Query on ARG | D [auth A] | ARGININE C6 H15 N4 O2 ODKSFYDXXFIFQN-BYPYZUCNSA-O |  | ||
| GOL Query on GOL | C [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.238 (Depositor), 0.242 (DCC)
- R-Value Work: 0.223 (Depositor), 0.223 (DCC)
- R-Value Observed: 0.223 (Depositor)
Space Group: P 63
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 90.965 | α = 90 |
| b = 90.965 | β = 90 |
| c = 99.379 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| XDS | data scaling |
| PHASER | phasing |
| Coot | model building |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-03-19 Deposition Author(s): Myllykoski, M., Arnesen, T.
| Funding Organization | Location | Grant Number |
|---|---|---|
| European Research Council (ERC) | European Union | 772039 |
Revision History (Full details and data files)
- Version 1.0: 2025-03-19
Type: Initial release
