Download MendeleyComparative analysis of hPARP9 macro domains
Fourkiotis, N.K., Chikunova, A., Tsika, C.A., Tsatsouli, A.S., Perrakis, A., Spyroulias, G.A.To be published.
9QYD | pdb_00009qyd
PARP9 Macro domain 1, Free form
- PDB DOI: https://doi.org/10.2210/pdb9QYD/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2025-04-17 Released: 2025-05-28
- Funding Organization(s): European Regional Development Fund, European Union (EU)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.91 Å
- R-Value Free: 0.235 (Depositor), 0.213 (DCC)
- R-Value Work: 0.187 (Depositor), 0.195 (DCC)
- R-Value Observed: 0.189 (Depositor)
Starting Model: in silico
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wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Protein mono-ADP-ribosyltransferase PARP9 | 203 | Homo sapiens | Mutation(s): 0 Gene Names: PARP9, BAL, BAL1 EC: 2.4.2 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8IXQ6 (Homo sapiens) Explore Q8IXQ6 Go to UniProtKB: Q8IXQ6 | |||||
PHAROS: Q8IXQ6 GTEx: ENSG00000138496 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8IXQ6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| MLI Query on MLI | C [auth A], D [auth A] | MALONATE ION C3 H2 O4 OFOBLEOULBTSOW-UHFFFAOYSA-L |  | ||
| GOL Query on GOL | B [auth A], E [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.91 Å
- R-Value Free: 0.235 (Depositor), 0.213 (DCC)
- R-Value Work: 0.187 (Depositor), 0.195 (DCC)
- R-Value Observed: 0.189 (Depositor)
Space Group: P 21 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 39.701 | α = 90 |
| b = 63.847 | β = 90 |
| c = 69.53 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| MOLREP | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-28 Deposition Author(s): Fourkiotis, N.K., Chikunova, A., Tsika, C.A., Tsatsouli, A.S., Perrakis, A., Spyroulias, G.A.
| Funding Organization | Location | Grant Number |
|---|---|---|
| European Regional Development Fund | European Union | 5002550-INSPIRED |
| European Union (EU) | European Union | 101087215-ESPERANCE |
| European Union (EU) | European Union | 101159708-MILESTONE |
| European Union (EU) | European Union | 101159708-iNEXT Discovery |
Revision History (Full details and data files)
- Version 1.0: 2025-05-28
Type: Initial release
