Download MendeleyThe RING domain of IDOL
Bradshaw, W.J., He, L., Guenther, F., Murphy, E.J.To be published.
9SA1 | pdb_00009sa1
The RING domain of IDOL
- PDB DOI: https://doi.org/10.2210/pdb9SA1/pdb
- Classification: LIGASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2025-08-07 Released: 2025-09-10
- Funding Organization(s): Alzheimers Research UK (ARUK)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.06 Å
- R-Value Free: 0.177 (Depositor), 0.177 (DCC)
- R-Value Work: 0.130 (Depositor), 0.130 (DCC)
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| E3 ubiquitin-protein ligase MYLIP | 78 | Homo sapiens | Mutation(s): 0 Gene Names: MYLIP, BZF1, IDOL, BM-023, PP5242 EC: 2.3.2.27 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8WY64 (Homo sapiens) Explore Q8WY64 Go to UniProtKB: Q8WY64 | |||||
PHAROS: Q8WY64 GTEx: ENSG00000007944 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8WY64 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZN Query on ZN | C [auth A], D [auth A], E [auth B], F [auth B] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.06 Å
- R-Value Free: 0.177 (Depositor), 0.177 (DCC)
- R-Value Work: 0.130 (Depositor), 0.130 (DCC)
Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 43.534 | α = 90 |
| b = 51.958 | β = 90 |
| c = 55.328 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| DIALS | data reduction |
| STARANISO | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-09-10 Deposition Author(s): Bradshaw, W.J., He, L., Guenther, F., Murphy, E.J.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Alzheimers Research UK (ARUK) | United Kingdom | ARUK2020DDI-OX |
| Alzheimers Research UK (ARUK) | United Kingdom | 520909 |
Revision History (Full details and data files)
- Version 1.0: 2025-09-10
Type: Initial release
