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Download New Poster: CSMs and PDB Structures
07/01 
Download this image of Computed Structure Models from AI/ML and PDB Experimental StructuresResearchers have long used the wealth of experimentally-determined structures available from the open-access PDB archive to understand basic principles of protein architecture. More recently, PDB structures have been used as training data for Artificial Intelligence/Machine Learning software tools (e.g., AlphaFold, RosettaFold, OpenFold) that are able to predict three-dimensional structures of proteins and design proteins with novel shapes and biochemical functions.
RCSB.org provides access to these Computed Structure Models from AI/ML (as symbolized on the computer screen in this image) alongside experimental PDB structures (symbolized in flasks).
Experimental structures and CSMs are clearly identified throughout RCSB.org in a similar manner: a dark-blue flask icon is used for PDB structures and a cyan computer icon for CSMs. Simultaneous delivery of PDB data and CSMs provides access to 3D structural information from across the human proteome, model organisms, and selected pathogens.
